RESOLVE
Resolve Chronic Inflammation and Achieve Healthy Aging by Understanding Non-regenerative Repair
| Coordinatore | MEDIZINISCHE UNIVERSITAET WIEN
Organization address
address: SPITALGASSE 23 contact info |
| Nazionalità Coordinatore | Austria [AT] |
| Sito del progetto | http://resolve.punkt-international.eu/ |
| Totale costo | 14˙173˙960 € |
| EC contributo | 10˙689˙714 € |
| Programma | FP7-HEALTH
Specific Programme "Cooperation": Health |
| Code Call | FP7-HEALTH-2007-A |
| Funding Scheme | CP-IP |
| Anno di inizio | 2008 |
| Periodo (anno-mese-giorno) | 2008-04-01 - 2013-09-30 |
Partecipanti
| # | ||||
|---|---|---|---|---|
| 1 |
MEDIZINISCHE UNIVERSITAET WIEN
Organization address
address: SPITALGASSE 23 contact info |
AT (WIEN) | coordinator | 0.00 |
| 2 |
AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS
Organization address
address: CALLE SERRANO 117 contact info |
ES (MADRID) | participant | 0.00 |
| 3 |
AIT Austrian Institute of Technology GmbH
Organization address
address: Donau-City-Strasse 1 contact info |
AT (WIEN) | participant | 0.00 |
| 4 |
BEN-GURION UNIVERSITY OF THE NEGEV
Organization address
address: Office of the President - Main Campus contact info |
IL (BEER SHEVA) | participant | 0.00 |
| 5 |
BIOTALENTUM TUDASFEJLESZTO KFT
Organization address
address: AULICH LAJOS UTCA 26 contact info |
HU (GOEDOELLO) | participant | 0.00 |
| 6 |
BRIGITTE ROHNER PUNKT
Organization address
address: "Grosse Schiffgasse, 5/23" contact info |
AT (WIEN) | participant | 0.00 |
| 7 |
CHRISTIAN-ALBRECHTS-UNIVERSITAET ZU KIEL
Organization address
address: OLSHAUSENSTRASSE 40 contact info |
DE (KIEL) | participant | 0.00 |
| 8 |
INSTYTUT MEDYCYNY WSI IM WITOLDA CHODZKI
Organization address
address: Jaczewskiego 2 contact info |
PL (LUBLIN) | participant | 0.00 |
| 9 |
INTEGROMICS SL ITG
Organization address
address: AVENIDA DE INNOVACION GRANADA PARQUE TECNOLOGIA CIENCAS DE LA SALUD 1 BIC contact info |
ES (ARMILLA -GRANADA) | participant | 0.00 |
| 10 |
POLITECNICO DI TORINO
Organization address
address: Corso Duca degli Abruzzi 24 contact info |
IT (TORINO) | participant | 0.00 |
| 11 |
PUNKT INTERNATIONAL GMBH
Organization address
address: LOWENGASSE 45/2 contact info |
AT (WIEN) | participant | 0.00 |
| 12 |
UNIVERSITA DEGLI STUDI DI VERONA
Organization address
address: VIA DELL ARTIGLIERE 8 contact info |
IT (VERONA) | participant | 0.00 |
| 13 |
UNIVERSITE CATHOLIQUE DE LOUVAIN
Organization address
address: Place De L'Universite 1 contact info |
BE (LOUVAIN LA NEUVE) | participant | 0.00 |
| 14 |
UNIVERSITY OF BRISTOL
Organization address
address: TYNDALL AVENUE SENATE HOUSE contact info |
UK (BRISTOL) | participant | 0.00 |
Mappa
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Obiettivo del progetto (Objective)
'RESOLVE has been outlined to better understand the regulatory networks that control the devel-opmental processes in organ repair and to identify mechanisms which cause the termination of regu-lar organ development leading to fibroproliferative wound healing. Fibroproliferative wound healing represents a major pathology in elderly people shifting regular organ development into progressive organ fibrosis with complete loss of organ function. Based on the identification of valuated molecu-lar targets of fibroproliferative repair, RESOLVE aims to create suitable treatment strategies to achieve healthy ageing in the elderly. In doing so, RESOLVE will create a significant impact on life quality of elderly people. RESOLVE’s outcomes will strengthen the competitiveness of European science and biotechnology industry and contribute to cost saving strategies in the health care sector. RESOLVE’s structured scientific approach combines as yet fragmented fields of research using model organisms which represent (a) different forms of wound healing, (b) different human diseases and (c) different genetic backgrounds, guaranteeing social and scientific relevance, modularity of re-search and the integration of existing biological knowledge, technical expertise and medical experi-ence. In addition, sequential generation of data during improvement or worsening ensures clinical relevance and leads to a stringent exploitation strategy. The sustainable outcomes of RESOLVE’s efforts will be: (A) the urgently needed diagnostic tool for fibroproliferative wound healing in various organs, (B) highly valuable transgenic animals offering test systems for fibroproliferative wound healing, and (C) a characterization of compounds capable of interfering with targets involved in fibroprolifera-tive repair.'
Introduzione (Teaser)
Ageing can be accompanied by impaired non-regenerative fibroproliferative tissue healing and chronic inflammation resulting in loss of organ function. EU-funded researchers sought to elucidate the underlying mechanisms involved in this process.
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