GENEVOSYN SIGNED
Reshuffling genes and genomes: from experimental evolution to synthetic biology in plants
Total Cost €
0EC-Contrib. €
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0GENEVOSYN project word cloud
Explore the words cloud of the GENEVOSYN project. It provides you a very rough idea of what is the project "GENEVOSYN" about.
Project "GENEVOSYN" data sheet
The following table provides information about the project.
| Coordinator |
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Project website | http://www.mpimp-golm.mpg.de/1997016/2_5_Million_Euro_for_innovative_plant_research |
| Total cost | 2˙500˙000 € |
| EC max contribution | 2˙500˙000 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2014-ADG |
| Funding Scheme | ERC-ADG |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-10-01 to 2020-09-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV | DE (Munich) | coordinator | 2˙500˙000.00 |
Map
Project objective
GENEVOSYN has three highly ambitious objectives that will enable the engineering of new generations of crop plants. The project consists of three complementary workpackages (WPs) and will use both synthetic genomes and naturally available genomes as raw material for novel biotechnology and synthetic biology approaches. It will employ experimental gene and genome transfer as well as recently discovered natural (horizontal) genome transfer processes to generate new crop varieties and species. In WP1, the plastid (chloroplast) will be developed as a highly efficient platform for synthetic biology applications in plants. This will be accomplished by pursuing bottom-up and top-down synthetic biology approaches. They include the construction of large synthetic multigene operons towards introducing new complex metabolic pathways into plants, and the design, synthesis, assembly and booting up of radically redesigned synthetic genomes that ultimately will allow us to expand the genetic code and thereby the amino acid repertoire of plant cells. In WP2, GENEVOSYN aims at developing a technology for mitochondrial genome engineering in plants. The possibility to alter the genetic information in plant mitochondria by transformation would revolutionize both basic and applied research on plant mitochondria, and pave the way to harnessing the enormous potential of mitochondrial biotechnology. Finally, WP3 will exploit recently discovered horizontal genome transfer processes for the creation of novel crop species and the improvement of existing ones. To this end, we will use grafting-assisted horizontal genome transfer between crop species in the nightshade family (Solanaceae) to (i) generate new combinations of nuclear and plastid genomes and determine the impact of the plastid genome and specific plastid genes on plant growth and stress tolerance, and (ii) produce novel (synthetic) species that arise from the combination of entire nuclear genomes of existing species.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Zhichao Li, Ralph Bock Rapid functional activation of a horizontally transferred eukaryotic gene in a bacterial genome in the absence of selection published pages: 6351-6359, ISSN: 0305-1048, DOI: 10.1093/nar/gkz370 |
Nucleic Acids Research 47/12 | 2020-04-15 |
| 2019 |
Stephanie Ruf, Joachim Forner, Claudia Hasse, Xenia Kroop, Stefanie Seeger, Laura Schollbach, Anne Schadach, Ralph Bock High-efficiency generation of fertile transplastomic Arabidopsis plants published pages: 282-289, ISSN: 2055-0278, DOI: 10.1038/s41477-019-0359-2 |
Nature Plants 5/3 | 2020-04-15 |
| 2018 |
Christian R Boehm, Ralph Bock Recent advances and current challenges in synthetic biology of the plastid genetic system and metabolism published pages: pp.00767.2018, ISSN: 0032-0889, DOI: 10.1104/pp.18.00767 |
Plant Physiology | 2019-04-03 |
| 2018 |
Zhichao Li, Ralph Bock Replication of bacterial plasmids in the nucleus of the red alga Porphyridium purpureum published pages: 1-8, ISSN: 2041-1723, DOI: 10.1038/s41467-018-05651-1 |
Nature Communications 9/1 | 2019-04-03 |
| 2018 |
Iman Tabatabaei, Cristina Dal Bosco, Marta Bednarska, Stephanie Ruf, Jörg Meurer, Ralph Bock A highly efficient sulfadiazine selection system for the generation of transgenic plants and algae published pages: 1-12, ISSN: 1467-7644, DOI: 10.1111/pbi.13004 |
Plant Biotechnology Journal | 2019-04-03 |
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