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HISENTS SIGNED

High level Integrated SEnsor for NanoToxicity Screening

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

HISENTS project word cloud

Explore the words cloud of the HISENTS project. It provides you a very rough idea of what is the project "HISENTS" about.

instrumentation multimodular manner flexible modifications connected grouping compounds realistic physiological combined hca risk introducing perform seven content hierarchically hazard toxicogenomics capacity nanomaterials pharmaceutical critical hierarchical platform maximise characterise nm innovative applicable flexibly profiling biological sensor molecular function model organisms extensive organ individual efficiency realised htp pbpk chip endpoints network parallel safety tools interaction interdisciplinary read vision microfluidic sensors screening representing hisents input pharmacokinetic quality tool dearth line simulated cell market modules flow vectorial physiologically quantitative throughput ing toxicity combinable nano

Project "HISENTS" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY OF LEEDS Organization address address: WOODHOUSE LANE city: LEEDS postcode: LS2 9JT website: www.leeds.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.hisents.eu
Total cost	6˙332˙825 €
EC max contribution	6˙332˙825 € (100%)
Programme	1. H2020-EU.2.1.2.2. (Ensuring the safe and sustainable development and application of nanotechnologies)
Code Call	H2020-NMP-2015-two-stage
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-04-01 to 2019-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY OF LEEDS UNIVERSITY OF LEEDS Organization address address: WOODHOUSE LANE city: LEEDS postcode: LS2 9JT website: www.leeds.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LEEDS)	coordinator	1˙411˙205.00
2	FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. Organization address address: HANSASTRASSE 27C city: MUNCHEN postcode: 80686 website: www.fraunhofer.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (MUNCHEN)	participant	899˙990.00
3	UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK UNIVERSITY COLLEGE CORK - NATIONAL UNIVERSITY OF IRELAND, CORK Organization address address: WESTERN ROAD city: Cork postcode: T12 YN60 website: www.ucc.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Cork)	participant	800˙960.00
4	TEL AVIV UNIVERSITY TEL AVIV UNIVERSITY Organization address address: RAMAT AVIV city: TEL AVIV postcode: 69978 website: http://www.tau.ac.il/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (TEL AVIV)	participant	631˙875.00
5	SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE SLOVENSKA TECHNICKA UNIVERZITA V BRATISLAVE Organization address address: VAZOVOVA 5 city: BRATISLAVA postcode: 81243 website: www.stuba.sk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SK (BRATISLAVA)	participant	508˙745.00
6	Blueprint Product Design Ltd Blueprint Product Design Ltd Organization address address: 38 Market Street city: Keighley postcode: BD21 5AD website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Keighley)	participant	500˙050.00
7	TECHNISCHE UNIVERSITAET WIEN TECHNISCHE UNIVERSITAET WIEN Organization address address: KARLSPLATZ 13 city: WIEN postcode: 1040 website: www.tuwien.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	368˙750.00
8	FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA FUNDACIO INSTITUT CATALA DE NANOCIENCIA I NANOTECNOLOGIA Organization address address: CAMPUS DE LA UAB EDIFICI Q ICN2 city: BELLATERRA (BARCELONA) postcode: 8193 website: www.icn.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BELLATERRA (BARCELONA))	participant	341˙250.00
9	BIOMEDICINSKE CENTRUM SLOVENSKEJ AKADEMIE VIED BIOMEDICINSKE CENTRUM SLOVENSKEJ AKADEMIE VIED Organization address address: DUBRAVSKA CESTA 9 city: BRATISLAVA postcode: 845 05 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SK (BRATISLAVA)	participant	300˙000.00
10	NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE NORSK INSTITUTT FOR LUFTFORSKNING STIFTELSE Organization address address: INSTITUTTVEIEN 18 city: KJELLER postcode: 2027 website: www.nilu.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (KJELLER)	participant	300˙000.00
11	UNIVERSITAT DES SAARLANDES UNIVERSITAT DES SAARLANDES Organization address address: CAMPUS city: SAARBRUCKEN postcode: 66123 website: www.uni-saarland.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (SAARBRUCKEN)	participant	270˙000.00
12	USTAV EXPERIMENTALNEJ ONKOLOGIE SLOVENSKEJ AKADEMIE VIED USTAV EXPERIMENTALNEJ ONKOLOGIE SLOVENSKEJ AKADEMIE VIED Organization address address: VLARSKA 7 city: BRATISLAVA postcode: 833 91 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SK (BRATISLAVA)	participant	0.00

Map

Project objective

The HISENTS vision is to address the problem of the dearth of high-quality tools for nano-safety assessment by introducing an innovative multimodular high throughput screening (HTP) platform including a set of individual modules each representing a critical physiological function connected and integrated in a hierarchical vectorial manner by a microfluidic network. The increase of the capacity to perform nano-safety assessment will be realised by innovative instrumentation developments for HTP and high content analysis (HCA) approaches. Toxicogenomics on chip is also one embedded objective. Our interdisciplinary approach focuses on tools to maximise the read-across and to assess applicable endpoints for advanced risk assessment of nanomaterials (NM). The main goal is thus to establish individual chip-based microfluidic tools as devices for (nano)toxicity screening which can be combined as an on-line HTP platform. Seven different chip-based sensor elements will be developed and hierarchically combined via a flow system to characterise toxicity pathways of NM. The HISENTS platform allows the grouping and identifying of NM. Parallel to the screening, the pathway and interaction of NM in biological organisms will be simulated using the physiologically based pharmacokinetic (PBPK) model. Using the different sensor modules from the molecular to cell to organ level, HISENTS can input quantitative parameters into the PBPK model resulting in an effective pathway analysis for NM and other critical compounds. The developed platform is crucial for realistic nano-safety assessment and will also find extensive application in pharmaceutical screening due to the flexible modifications of the HTP platform. The specific objective is the development of a multimodular HTP platform as new a screening tool for enhancing the efficiency of hazard profiling. Currently, no such flexible, easy-to-use screening platform with flexibly combinable chip-based sensors is available on the market.

Publications

List of publications.
year	authors and title	journal	last update
2017	GÃ¡belovÃ¡ Alena, Kozics KatarÃna, Å ramkovÃ¡ Monika, SranÄÃkovÃ¡ AnnamÃ¡ria, SmolkovÃ¡ BoÅ¾ena A multimodular high throughput screening platform for nano-safety assessment published pages: 39, ISSN: , DOI:	Genetic Toxicology and Cancer Prevention	2019-08-29
2017	Gottardo S, et al NANoREG framework for the safety assessment of Nanomaterials published pages: , ISSN: , DOI:		2019-08-29
2018	Eilenberger, Christoph; Kratz, Sebastian Rudi Adam; Rothbauer, Mario; Ehmoser, Eva-Kathrin; Ertl, Peter; KÃ¼pcÃ¼, Seta Optimized alamarBlue assay protocol for drug dose-response determination of 3D tumor spheroids published pages: 781-787, ISSN: 2215-0161, DOI: 10.1016/j.mex.2018.07.011/128	MethodsX 2	2019-08-29
2018	Verena Charwat, Isabel Olmos Calvo, Mario Rothbauer, Sebastian Rudi Adam Kratz, Christian Jungreuthmayer, JÃ¼rgen Zanghellini, Johannes Grillari, Peter Ertl Combinatorial in Vitro and in Silico Approach To Describe Shear-Force Dependent Uptake of Nanoparticles in Microfluidic Vascular Models published pages: 3651-3655, ISSN: 0003-2700, DOI: 10.1021/acs.analchem.7b04788	Analytical Chemistry 90/6	2019-08-29
2018	Velten, T.; Knoll, T.; Kohl, Y; Hesler, M.; Biehl, M.; Spring, S.; Wagner, S. A multi-modular microfluidic in vitro platform for interconnecting multiple organs published pages: , ISSN: , DOI:	International Organ-on-Chip Symposium	2019-08-29
2018	Lorenzo Russo, Florind MerkoÃ§i, Javier Patarroyo, Jordi Piella, Arben MerkoÃ§i, Neus G. BastÃºs, Victor Puntes Time- and Size-Resolved Plasmonic Evolution with nm Resolution of Galvanic Replacement Reaction in AuAg Nanoshells Synthesis published pages: 5098-5107, ISSN: 0897-4756, DOI: 10.1021/acs.chemmater.8b01488	Chemistry of Materials 30/15	2019-08-29
2019	Tran TA, Hesler M, Moriones O, Jimeno-Romero A, Fischer B, Bastus N, Puntes V, Wagner S, Kohl Y, Gentile L Iron oxide nanoparticles: effects on regeneration and homeostasis in planarians published pages: , ISSN: 1868-596X, DOI:	ALTEX	2019-08-29
2019	Sebastian Kratz, Christoph Eilenberger, Patrick Schuller, Barbara Bachmann, Sarah Spitz , Mario Rothbauer. Characterization of four functional biocompatible pressure-sensitive adhesives for rapid prototyping of cell-based lab-on-a-chip and organ-on-a-chip systemsunder Revisions at Nature Scientific Reports published pages: , ISSN: 2045-2322, DOI:	Nature Scientific Reports	2019-08-29
2018	Alena Gabelova, Katarina Kozics, Lucyna Kapka-Skrzypczak, Marcin Kruszewski, Monika Sramkova Nephrotoxicity: Topical issue published pages: , ISSN: 1383-5718, DOI: 10.1016/j.mrgentox.2018.11.012	Mutation Research/Genetic Toxicology and Environmental Mutagenesis	2019-08-29
2018	Lorenzo Russo, Juan Leva Bueno, Jose Francisco Bergua, Monica Costantini, Marco Giannetto, Victor Puntes, Alfredo de la Escosura-MuÃ±iz, Arben MerkoÃ§i Low-Cost Strategy for the Development of a Rapid Electrochemical Assay for Bacteria Detection Based on AuAg Nanoshells published pages: 18849-18856, ISSN: 2470-1343, DOI: 10.1021/acsomega.8b02458	ACS Omega 3/12	2019-08-29
2018	Katharina Netzer, Galateja Jordakieva, Angelika M. Girard, Alexandra C. Budinsky, Alexander Pilger, Lukas Richter, Nadezhda Kataeva, Joerg Schotter, Jasminka Godnic-Cvar, Peter Ertl Next-Generation Magnetic Nanocomposites: Cytotoxic and Genotoxic Effects of Coated and Uncoated Ferric Cobalt Boron (FeCoB) Nanoparticles In Vitro published pages: 355-363, ISSN: 1742-7835, DOI: 10.1111/bcpt.12918	Basic & Clinical Pharmacology & Toxicology 122/3	2019-08-29
2019	E. Elje, M. Hesler, E. RundÃ©n-Pran, P. Mann, E. Mariussen, S. Wagner, M. Dusinska, Y. Kohl The comet assay applied to HepG2 liver spheroids published pages: , ISSN: 1383-5718, DOI:	Mutation Research - Genetic Toxicology and Environmental Mutagenesis	2019-08-29
2019	P. Simon et al. Quantum-chemical studies of rutile nanoparticles toxicity I. Defect-free rod-like model clusters published pages: , ISSN: 1931-7573, DOI:	Nanoscale Research	2019-08-29
2019	Monika Sramkova, Katarina Kozics, Vlasta Masanova, Iveta Uhnakova, Filip Razga, Veronika Nemethova, Petra Mazancova, Lucyna Kapka-Skrzypczak, Marcin Kruszewski, Marta Novotova, Victor F. Puntes, Alena Gabelova Kidney nanotoxicity studied in human renal proximal tubule epithelial cell line TH1 published pages: , ISSN: 1383-5718, DOI: 10.1016/j.mrgentox.2019.01.012	Mutation Research/Genetic Toxicology and Environmental Mutagenesis	2019-08-29
2017	Dusinska M, El-Yamani N, Elje E, RundÃ©n Pran E Safety assessment of nanoparticles with in vitro approaches published pages: , ISSN: , DOI:	Current Trends in Nanotoxicology: Implications for Environmental & Human Health	2019-08-29
2018	Simon, P. \"Chapter entitled \"\"Toxicita Nanomaterialov\"\"\" published pages: , ISSN: , DOI:	Chemicke Latky A Zdravie	2019-08-29
2018	Barbara Bachmann, Sarah Spitz, Mario Rothbauer, Christian Jordan, Michaela Purtscher, Helene Zirath, Patrick Schuller, Christoph Eilenberger, Syed Faheem Ali, Severin MÃ¼hleder, Eleni Priglinger, Michael Harasek, Heinz Redl, Wolfgang Holnthoner, Peter Ertl Engineering of three-dimensional pre-vascular networks within fibrin hydrogel constructs by microfluidic control over reciprocal cell signaling published pages: 42216, ISSN: 1932-1058, DOI: 10.1063/1.5027054	Biomicrofluidics 12/4	2019-08-29
2017	Bamiduro, Faith, Hossain, Mohammad, Chankhunthod, Navadecho, Domenech, Natalia, Mohamadi, Shahrzard, Hondow, Nicole, Milne, Steven, Drummond-Brydson, Rik, and Nelson, Andrew. Bio-friendly Synthesis and Shape Modification of Metal and Metal Oxide Nanoparticles for Bio-sensing Applications published pages: , ISSN: , DOI:	13th international conference on materials chemistry (IMC), organised by the Royal Society of Chemistry (RSC)	2019-08-29
2018	Mann P., Straskraba S., Wagner S., Kohl Y. Effect of nanoparticles on liver function: 2D versus 3D culture published pages: , ISSN: , DOI:	NanoTox 2018 Book of Abstracts	2019-08-29
2018	M.Sramkova, K.Kozics, P. Pechacova, A. Srancikova, F. Razga, V. Nemethova, M. Novotova, N. Ludwig, M. Ursinyova, B. Smolkova, E. Meese, A. Gabelova The Risks and Benefits of Nanotechnologies - Genetic and Epigenetic Toxicity published pages: , ISSN: , DOI:		2019-08-29
2018	Marco Werner, Thorsten Auth, Paul A. Beales, Jean Baptiste Fleury, Fredrik HÃ¶Ã¶k, Holger Kress, Reid C. Van Lehn, Marcus MÃ¼ller, Eugene P. Petrov, Lev Sarkisov, Jens-Uwe Sommer, Vladimir A. Baulin Nanomaterial interactions with biomembranes: Bridging the gap between soft matter models and biological context published pages: 28501, ISSN: 1559-4106, DOI: 10.1116/1.5022145	Biointerphases 13/2	2019-08-29
2019	N. William, A. Nelson, S. Gutsell, G. Hodges, J. Rabone, A. Teixeira Hg-supported phospholipid monolayer as rapid screening device for low molecular weight narcotic compounds in water published pages: 98-107, ISSN: 0003-2670, DOI:	Analytica Chimica Acta	2019-08-29
2019	Marina Berditsch, Sergii Afonin, Jennifer Reuster, Hannah Lux, Kristina Schkolin, Oleg Babii,Dmytro S. Radchenko, Issah Abdullah, Nicola William, Volker Middel, Uwe StrÃ¤hle, Andrew Nelson, Klara Valko and Anne S. Ulrich Supreme activity of gramicidin S against resistant, persistent and biofilm cells of staphylococci and enterococci published pages: , ISSN: 2045-2322, DOI:	Nature: Scientific reports	2019-08-29
2019	Mario Rothbauer, Julie M Rosser, Helene Zirath, Peter Ertl Tomorrow today: organ-on-a-chip advances towards clinically relevant pharmaceutical and medical in vitro models published pages: 81-86, ISSN: 0958-1669, DOI: 10.1016/j.copbio.2018.08.009	Current Opinion in Biotechnology 55	2019-08-29
2018	Neus G. BastÃºs, VÃctor Puntes Nanosafety: Towards Safer Nanoparticles by Design published pages: 4587-4601, ISSN: 0929-8673, DOI: 10.2174/0929867324666170413124915	Current Medicinal Chemistry 25/35	2019-08-29
2018	M. Sramkova, K. Kozics, P. Pechacova, K. Kopecka, M. Novotova, A. Gabelova Renal proximal tubule epithelial cell line TH1 as a tool to study the toxicity of xenobiotics. published pages: , ISSN: , DOI:	4th International Congress on Occupational & Environmental Toxicology	2019-08-29
2019	Vlasta Zavisova, Martina Koneracka, Alena Gabelova, Barbora Svitkova, Monika Ursinyova, Martina Kubovcikova, Iryna Antal, Iryna Khmara, Alena Jurikova, Matus Molcan, MiloÅ¡ OgnjanoviÄ‡, Bratislav AntiÄ‡, Peter Kopcansky Effect of magnetic nanoparticles coating on cell proliferation and uptake published pages: 66-73, ISSN: 0304-8853, DOI: 10.1016/j.jmmm.2018.09.116	Journal of Magnetism and Magnetic Materials 472	2019-08-29
2019	Heba A. Mohamed, Samantha Shepherd, Nicola William, Helen A. Blundell,Madhurima Das,Christopher M. Pask, Benjamin R. M. Lake, Roger M. Phillips,Andrew Nelson, and Charlotte E. Willans. Detection of silver(I)-N-heterocyclic carbene complexes derived from clotrimazole by an artificial membrane-based biosensor and correlation with antiproliferative activity. In preparation. published pages: , ISSN: 0022-2623, DOI:	Journal of Medicinal Chemistry	2019-08-29
2018	Denise Mandt, Peter Gruber, Marica Markovic, Maximillian Tromayer, Mario Rothbauer, Sebastian Rudi Adam Krayz, Faheem Ali, Jasper Van Hoorick, Wolfgang Holnthoner, Severin MÃ¼hleder, Peter Dubruel, Sandra Van Vlierberghe, Peter Ertl, Robert Liska, Aleksandr Ovsianikov Fabrication of placental barrier structures within a microfluidic device utilizing two-photon polymerization published pages: 1-12, ISSN: 2424-8002, DOI: 10.18063/ijb.v4i2.144	International Journal of Bioprinting 4/2	2019-08-29
2018	Lorenzo Russo, Victor Puntes, Arben MerkoÃ§i Tunable electrochemistry of gold-silver alloy nanoshells published pages: 6336-6345, ISSN: 1998-0124, DOI: 10.1007/s12274-018-2157-y	Nano Research 11/12	2019-08-29
2017	Elvira Fantechi, Alejandro G. Roca, Borja SepÃºlveda, Pau Torruella, Sonia EstradÃ©, Francesca PeirÃ³, Emerson Coy, Stefan Jurga, Neus G. BastÃºs, Josep NoguÃ©s, VÃctor Puntes Seeded Growth Synthesis of Auâ€“Fe 3 O 4 Heterostructured Nanocrystals: Rational Design and Mechanistic Insights published pages: 4022-4035, ISSN: 0897-4756, DOI: 10.1021/acs.chemmater.7b00608	Chemistry of Materials 29/9	2019-08-29
2017	Jordi Piella, Florind MerkoÃ§i, Aziz GenÃ§, Jordi Arbiol, Neus G. BastÃºs, Victor Puntes Probing the surface reactivity of nanocrystals by the catalytic degradation of organic dyes: the effect of size, surface chemistry and composition published pages: 11917-11929, ISSN: 2050-7488, DOI: 10.1039/c7ta01328k	Journal of Materials Chemistry A 5/23	2019-08-29
2018	Ogurtsov, V. I. and Todorovic, M. Automated Electrochemical Sensing Systems for Real Time Monitoring and Detection of Chemical Species published pages: 83, ISSN: , DOI:	Abstract book of the 1st International Conference on Nanotechnologies and Bionanoscience (NanoBio 2018)	2019-08-29
2018	Kohl Y Advanced models and detection systems for evaluating immunotoxicity of nanomaterials in health and disease published pages: 526, ISSN: 0378-4274, DOI:	Toxicology Letters	2019-08-29
2018	Y Kohl, M. Hesler, S. Spring, T. Velten, S. Wagner, T. Knoll Chip-based platform: An in vitro approach for toxicity screening published pages: , ISSN: , DOI:	OpenTox EURO 2018	2019-08-29
2017	Drlickova M, Smolkova B, Runden-Pran E, Dusinska M Health Hazard and Risk Assessment of Nanoparticles Applied in Biomedicine published pages: , ISSN: , DOI:	Toxicology No. 35 Nanotoxicology: Experimental and Computational Perspectives Edited by Alok Dhawan, Diana Anderson and Rishi Shanker No. 35, Chapter 6	2019-06-18
2017	Å imon P. Migration of nanoparticles from packaging and a sensor for the nanoparticles toxicity published pages: , ISSN: , DOI:	COST Action FP1405 Meeting - Conference Application & Communication of Active and Intelligent Packaging	2019-06-18
2017	Dusinska M, El-Yamani N, Elje E, RundÃ©n Pran E Genotoxicity of engineered nanoparticles published pages: , ISSN: , DOI:	Conference Proceedings, EUROTOX, Bratislava, Slovakia 10. - 13.9.17	2019-06-18
2017	GÃ¡belovÃ¡ Alena, MesÃ¡roÅ¡ovÃ¡ Monika, BÃ¡belovÃ¡ Andrea, Kozics KatarÃna, SedlÃ¡ÄkovÃ¡ Eva, NÃ©methovÃ¡ V, SvitkovÃ¡ Barbora, RÃ¡zga Filip, ZÃ¡viÅ¡ovÃ¡ V, KonerackÃ¡ M, UrsÃnyovÃ¡ M, ÄŒiampor F. Searching for appropriate in vitro kidney model to measure the genotoxicity of xenobiotics and nanoparticles published pages: 65, ISSN: , DOI:	NANOCON 2017	2019-06-18
2016	Å imon P. Nanotoxicity and the migration of nanoparticles from packaging to food published pages: 187, ISSN: , DOI:	6th International Symposium on Food Packaging 2016 â€“ Scientific Developments Supporting Safety and Innovation	2019-06-18
2017	GÃ¡belovÃ¡ Alena, Kozics KatarÃna, Å ramkovÃ¡ Monika, SranÄÃkovÃ¡ AnnamÃ¡ria, SmolkovÃ¡ BoÅ¾ena A multimodular hight throughput screening platform for nano-safety assassment published pages: 39, ISSN: , DOI:	Genetic Toxicology and Cancer Prevention	2019-06-18
2017	Dusinska M, Gabelova A, El Yamani N, Elje E, RundÃ©n-Pran E Small, Smart and Safe (3S) Nanoparticles: How to address their Risk Assessment with in vitro (3R) approaches published pages: , ISSN: , DOI:	Books of Abstracts, Genetic toxicology and Cancer Prevention, 12 - 15 June, 2017 Smolenice, Cancer Research Institute, Bratislava	2019-06-18
2017	Mario Rothbauer, Nilaykumar Patel, Hajnalka Gondola, Monika Siwetz, Berthold Huppertz, Peter Ertl A comparative study of five physiological key parameters between four different human trophoblast-derived cell lines published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-06364-z	Scientific Reports 7/1	2019-06-18
2017	Å imon P., Dubaj T., CibulkovÃ¡ Z. & VykydalovÃ¡ A Nanomaterials and their toxicity published pages: 152, ISSN: , DOI:	69. Zjazd chemikov, VysokÃ© Tatry	2019-06-18
2017	SranÄÃkovÃ¡ AnnamÃ¡ria, Å ramkovÃ¡ Monika, Kozics KatarÃna, SmolkovÃ¡ BoÅ¾ena, GÃ¡belovÃ¡ Alena Searching for appropriate in vitro kidney model to measure drug-induced toxicity published pages: 40, ISSN: , DOI:	Genetic Toxicology and Cancer Prevention	2019-06-18
2017	GÃ¡belovÃ¡ Alena, SranÄÃkovÃ¡ AnnamÃ¡ria, Å ramkovÃ¡ Monika, Kozics KatarÃna, SmolkovÃ¡ BoÅ¾ena The impact of inorganic nanomaterials on global DNA methylation published pages: 65-66, ISSN: , DOI:	ICAW 2017	2019-06-18
2017	A. Rashid, A. Vakurov, S. Mohamadi, D. Sanver, A. Nelson Substituents modulate biphenyl penetration into lipid membranes published pages: 712-721, ISSN: 0005-2736, DOI: 10.1016/j.bbamem.2017.01.023	Biochimica et Biophysica Acta (BBA) - Biomembranes 1859/5	2019-06-18
2017	Å ramkovÃ¡ Monika, GÃ¡belovÃ¡ Alena, Kozics KatarÃna, SranÄÃkovÃ¡ AnnamÃ¡ria Human renal proximal tubule epithelial cell line TH1 as a promising in vitro kidney model to predict the genotoxicity of xenobiotics and nonoparticles published pages: 24, ISSN: , DOI:	ICAW 2017	2019-06-18
2017	Maria Dusinska, Jana Tulinska, Naouale El Yamani, Miroslava Kuricova, Aurelia Liskova, Eva Rollerova, Elise RundÃ©n-Pran, Bozena Smolkova Immunotoxicity, genotoxicity and epigenetic toxicity of nanomaterials: New strategies for toxicity testing? published pages: 797-811, ISSN: 0278-6915, DOI: 10.1016/j.fct.2017.08.030	Food and Chemical Toxicology 109	2019-06-18
2017	Å imon P., Dubaj T., VykydalovÃ¡ A. & CibulkovÃ¡ Z Sensor for the nanomaterial toxicity published pages: 512, ISSN: , DOI:	60. Zjazd Naukowy Polskiego Towarzystwa Chemicznego	2019-06-18
2017	Mario Rothbauer, Helene Zirath, Peter Ertl Recent advances in microfluidic technologies for cell-to-cell interaction studies published pages: , ISSN: 1473-0197, DOI: 10.1039/C7LC00815E	Lab on a Chip	2019-06-18
2017	Å ramkovÃ¡ Monika, Kozics KatarÃna, SranÄÃkovÃ¡ AnnamÃ¡ria, GÃ¡belovÃ¡ Alena Searching for appropriate in vitro kidney model to measure the genotoxicity of xenobiotics and nanoparticles published pages: 81, ISSN: , DOI:	In vitro 3-D Total Cell Guidance and Fitness	2019-06-18
2017	Dubaj T., Å imon P., CibulkovÃ¡ Z., VykydalovÃ¡ A. & Breza M Developing a PBPK model for the High Level Integrated Sensor for Nanotoxicity Screening (HISENTS) platform published pages: 146, ISSN: , DOI:	9th International Conference on Nanomaterials â€“ Research and Application NANOCON 2017	2019-06-18
2017	Bozena Smolkova, Maria Dusinska, Alena Gabelova Nanomedicine and epigenome. Possible health risks published pages: 780-796, ISSN: 0278-6915, DOI: 10.1016/j.fct.2017.07.020	Food and Chemical Toxicology 109	2019-06-18
2017	M Ilett, F Bamiduro, O Matar, A Brown, R Brydson, N Hondow Cryo-STEM-EDX spectroscopy for the characterisation of nanoparticles in cell culture media published pages: 12006, ISSN: 1742-6588, DOI: 10.1088/1742-6596/902/1/012006	Journal of Physics: Conference Series 902	2019-06-18
2017	Dusinska M, El-Yamani N, Elje E, RundÃ©n Pran E Safety assessment of nanoparticles with in vitro approaches published pages: , ISSN: , DOI:	Â CURRENT TRENDS IN NANOTOXICOLOGY: IMPLICATIONS FOR ENVIRONMENTAL & HUMAN HEALTH	2019-06-18
2017	Dubaj T., Å imon P., CibulkovÃ¡ Z. & VykydalovÃ¡ A A minimal physiologically based pharmacokinetic model for nanoparticles biodistribution published pages: 78-79, ISSN: , DOI:		2019-06-18
2017	Gottardo S, et al NanoReg framework for the safety assessment of Nanomaterials (Policy Report) published pages: , ISSN: , DOI:	European Commission April 2017	2019-06-18
2017	SmolkovÃ¡ BoÅ¾ena, GÃ¡belovÃ¡ Alena, Å ramkovÃ¡ Monika, Kozics KatarÃna, SranÄÃkovÃ¡ AnnamÃ¡ria, DuÅ¡inskÃ¡ MÃ¡ria Epigenetic changes induced by nanomaterials and possible impact on health published pages: 38, ISSN: , DOI:	Genetic Toxicology and Cancer Prevention	2019-06-18
2017	Å imon P., Dubaj T., VykydalovÃ¡ A. & CibulkovÃ¡ Z. High level integrated sensor for nanotoxicity screening published pages: 67, ISSN: , DOI:	9th International Conference on Nanomaterials â€“ Research and Application NANOCON 2017	2019-06-18
2016	Didem Sanver, Brent S. Murray, Amin Sadeghpour, Michael Rappolt, Andrew L. Nelson Experimental Modeling of Flavonoidâ€“Biomembrane Interactions published pages: 13234-13243, ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.6b02219	Langmuir 32/49	2019-06-18
2018	Kohl Y, Knoll T, Hesler M, Neson AL Multimodular fluidic in vitro nanosafety screening published pages: , ISSN: , DOI:	3rd German Toxicity Summit	2019-08-29
2018	Dubaj, T., Simon, P., Cibulkova, Z., Vykydalova, A., Belak, M. Comparison of PBPK models describing the distribution of nanoparticles in mammals published pages: 43409, ISSN: , DOI:	6th International Conference nanoSAFE 2018	2019-08-29
2017	M Ilett, F Bamiduro, O Matar, A Brown, R Brydson, N Hondow Cryo-STEM-EDX spectroscopy for the characterisation of nanoparticles in cell culture media. published pages: , ISSN: 1742-6588, DOI:	Journal of Physics: Conference Series	2019-08-29
2018	Ashi Rashid, Alexandre Vakurov, Andrew Nelson Phospholipid bilayers at the mercury (Hg)/water interface published pages: 152-161, ISSN: 0013-4686, DOI:	Electrochimica Acta	2019-08-29
2018	Kohl Y Advanced models and detection systems for evaluating immunotoxicity of nanomaterials in health and disease published pages: , ISSN: , DOI:	Eurotox 2018 Book of Abstracts	2019-08-29
2019	Rothbauer et al. FTIR Spectroscopy as a novel tool for investigation of glucose transport and transport inhibition in human in vitro barrier models - under revision published pages: , ISSN: 0003-2654, DOI:	The Analyst	2019-08-29
2018	Hesler M., A.T. Tran, Kohl Y. Toxicity studies of iron oxide nanoparticles in planarian published pages: , ISSN: , DOI:	NanoTox 2018	2019-08-29
2018	Faith Bamiduro, Nicola William, Nicole Hondow, Steven Milne, Andrew Nelson, Rik Drummond-Brydson Hydrothermal Synthesis of Silver Nanoparticles for High Throughput Biosensing Applications. published pages: 861-866, ISSN: 2059-8521, DOI:	MRS Advances 3	2019-08-29
2018	A. Gabelova, M. Sramkova, K. Kozics, P. Pechacova, K. Kopecka, T. Knoll and Y.L. Kohl A reliable platform for the determination of nephrotoxicity in vitro published pages: , ISSN: , DOI:		2019-08-29
2018	Hesler M., Kohl Y., Knoll T, Spring S., Wagner S., Velten T Advanced in vitro cell culture module for long-term cultivation and toxicity screening of nanomaterials published pages: , ISSN: , DOI:	3rd Nanosafety Forum for Young Scientists	2019-08-29
2017	Knoll, T.; Kohl, Y.; Hesler, M.; Wagner, S.; Velten, T Multi-modular in vitro platform for evaluating the effects of nanoparticles on the human body published pages: , ISSN: , DOI:	NanoBio&Med 2017	2019-08-29
2017	Dusinska M, El-Yamani N, Elje E, RundÃ©n Pran E Genotoxicity of engineered nanoparticles published pages: , ISSN: , DOI:	EUROTOX Conference	2019-08-29
2017	Dubaj T., Å imon P., CibulkovÃ¡ Z. & VykydalovÃ¡ A A minimal physiologically based pharmacokinetic model for nanoparticles biodistribution published pages: 78-79, ISSN: , DOI:	69. Zjazd chemikov	2019-08-29
2018	Ogurtsov, V. I.; Twomey, K. and Todorovic, M. Electrochemical sensing system for environmental applications published pages: 90, ISSN: , DOI:	Abstract Book of International Conference Interface Against Pollution (IAP 2018)	2019-08-29
2018	Zirath, Helene; Rothbauer, Mario; Spitz, Sarah; Bachmann, Barbara; Jordan, Christian; MÃ¼ller, Bernhard; Ehgartner, Josef; Priglinger, Eleni; MÃ¼hleder, Severin; Redl, Heinz; Holnthoner, Wolfgang; Harasek, Michael; Mayr, Torsten; Ertl, Peter Every Breath You Take: Non-invasive Real-Time Oxygen Biosensing in Two- and Three-Dimensional Microfluidic Cell Models published pages: 815-826, ISSN: 1664-042X, DOI: 10.3389/fphys.2018.00815/128	Frontiers in Physiology 4	2019-08-29

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