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INSTRUCT-ULTRA SIGNED

Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

INSTRUCT-ULTRA project word cloud

Explore the words cloud of the INSTRUCT-ULTRA project. It provides you a very rough idea of what is the project "INSTRUCT-ULTRA" about.

speed pilot eastern era groups engaging american reinforce ago modes business science status engagement biology whilst efta positioning industry quality instruct asian ultra integrating giving sustainability reliability benefit service outside standards adjust starting infrastructure remotely membership countries roadmap life earn global south alongside services sometimes expand efficient accelerate links interface trusted excellence transition scope parties of workflows industrialised efficiency data resource operations community cooperative plan academia rapid expanded expanding strategy efficiencies foundations capture demand engage communities trust baseline structural eric consolidate updating bilateral african

Project "INSTRUCT-ULTRA" data sheet

The following table provides information about the project.

Coordinator	INSTRUCT ACADEMIC SERVICES LIMITED Organization address address: UNIVERSITY OF OXFORD OFFICES WELLINGTON SQUARE city: OXFORD postcode: OX1 2JD website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://www.instruct-ultra.eu
Total cost	3˙950˙000 €
EC max contribution	3˙950˙000 € (100%)
Programme	1. H2020-EU.1.4.1.1. (Developing new world-class research infrastructures)
Code Call	H2020-INFRADEV-2016-1
Funding Scheme	CSA
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2020-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	INSTRUCT ACADEMIC SERVICES LIMITED INSTRUCT ACADEMIC SERVICES LIMITED Organization address address: UNIVERSITY OF OXFORD OFFICES WELLINGTON SQUARE city: OXFORD postcode: OX1 2JD website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	coordinator	419˙088.00
2	THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD Organization address address: WELLINGTON SQUARE UNIVERSITY OFFICES city: OXFORD postcode: OX1 2JD website: www.ox.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (OXFORD)	participant	928˙208.00
3	CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE CONSORZIO INTERUNIVERSITARIO RISONANZE MAGNETICHE DI METALLO PROTEINE Organization address address: PIAZZA SAN MARCO 4 city: FIRENZE postcode: 50121 website: www.cerm.unifi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (FIRENZE)	participant	440˙000.00
4	UNIVERSITEIT UTRECHT UNIVERSITEIT UTRECHT Organization address address: HEIDELBERGLAAN 8 city: UTRECHT postcode: 3584 CS website: www.uu.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (UTRECHT)	participant	390˙000.00
5	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	357˙000.00
6	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	207˙450.00
7	Masarykova univerzita Masarykova univerzita Organization address address: Zerotinovo namesti 9 city: BRNO STRED postcode: 60177 website: http://www.muni.cz contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CZ (BRNO STRED)	participant	200˙000.00
8	JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN JOHANN WOLFGANG GOETHE-UNIVERSITATFRANKFURT AM MAIN Organization address address: THEODOR W ADORNO PLATZ 1 city: FRANKFURT AM MAIN postcode: 60323 website: www.uni-frankfurt.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (FRANKFURT AM MAIN)	participant	160˙252.00
9	VIB VZW VIB VZW Organization address address: RIJVISSCHESTRAAT 120 city: ZWIJNAARDE - GENT postcode: 9052 website: www.vib.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (ZWIJNAARDE - GENT)	participant	138˙000.00
10	KAROLINSKA INSTITUTET KAROLINSKA INSTITUTET Organization address address: Nobels Vag 5 city: STOCKHOLM postcode: 17177 website: www.ki.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (STOCKHOLM)	participant	110˙000.00
11	AARHUS UNIVERSITET AARHUS UNIVERSITET Organization address address: NORDRE RINGGADE 1 city: AARHUS C postcode: 8000 website: www.au.dk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (AARHUS C)	participant	100˙000.00
12	CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED CHEMICKY USTAV SLOVENSKEJ AKADEMIEVIED Organization address address: DUBRAVSKA CESTA 9 city: BRATISLAVA postcode: 845 website: www.chem.sk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SK (BRATISLAVA)	participant	100˙000.00
13	ETHNIKO IDRYMA EREVNON ETHNIKO IDRYMA EREVNON Organization address address: VAS KONSTANTINOU 48 city: ATHINA postcode: 11635 website: www.eie.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	100˙000.00
14	OULUN YLIOPISTO OULUN YLIOPISTO Organization address address: PENTTI KAITERAN KATU 1 city: OULU postcode: 90014 website: www.oulu.fi contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FI (OULU)	participant	100˙000.00
15	UNIVERSIDADE NOVA DE LISBOA UNIVERSIDADE NOVA DE LISBOA Organization address address: CAMPUS DE CAMPOLIDE city: LISBOA postcode: 1099 085 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (LISBOA)	participant	100˙000.00
16	WEIZMANN INSTITUTE OF SCIENCE WEIZMANN INSTITUTE OF SCIENCE Organization address address: HERZL STREET 234 city: REHOVOT postcode: 7610001 website: www.weizmann.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (REHOVOT)	participant	100˙000.00
17	INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA Organization address address: Avenida da Republica, Estacao Agronomica Nacional city: OEIRAS postcode: 2784-505 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (OEIRAS)	participant	0.00

Map

Project objective

Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale and reliability of the infrastructure. Instruct-Ultra will deliver these alongside the transition to ERIC legal status and rapid developments in, and increased demand for, integrated structural biology infrastructure. These advances in the scale and speed of delivery will earn further trust within the life science community. One focus will to expand membership to Eastern European states and EFTA countries, integrating their structural biology communities into Instruct and providing new opportunities to support research excellence and raise standards. Opportunities for engaging with industrialised and developing countries outside the ERA will build on existing cooperative work between Instruct and Asian, African and South American countries to establish strong bilateral programmes of benefit to both parties, giving Instruct better engagement in emerging global challenges and positioning Instruct as a trusted global resource for high quality structural biology services. Starting from baseline operations four years ago Instruct has now identified key areas of service which should be expanded, new potential user groups, and opportunities for more reliable, efficient and sometimes remotely used workflows. Instruct-Ultra will therefore test new modes of access and pilot new service methods in high demand areas to accelerate access for more users. Instruct-Ultra will reinforce Instruct operations by updating and expanding the business plan and structural biology roadmap, whilst improving the interface with academia and industry as a strategy to sustainability.

Deliverables

List of deliverables.
Outreach programme for new academic communities including an information pack	Websites, patent fillings, videos etc.	2019-06-05 14:49:45
Publication of a position paper on the operation of NMR services and RIs in general as a guide for users in collaboration with WP3	Documents, reports	2019-06-05 14:49:45
Process for establishing joint activities with new countries and formalising an agreement defining the shared programme	Documents, reports	2019-06-05 14:49:45
Plan a programme for review of Instruct infrastructure with external review panel	Documents, reports	2019-06-05 14:49:45
Dissemination, outreach and exploitation plan submitted to Executive Committee for review	Documents, reports	2019-06-05 14:49:45
Call 1 launched for developing new service provision of existing technologies and selection of qualifying projects	Other	2019-06-05 14:49:45

Take a look to the deliverables list in detail: detailed list of INSTRUCT-ULTRA deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2020	Antonio SchirÃ², Azzurra Carlon, Giacomo Parigi, Garib Murshudov, Vito Calderone, Enrico Ravera, Claudio Luchinat On the complementarity of X-ray and NMR data published pages: 100019, ISSN: 2590-1524, DOI: 10.1016/j.yjsbx.2020.100019	Journal of Structural Biology: X 4	2020-03-05
2019	Leonid Andronov, Khalid Ouararhni, Isabelle Stoll, Bruno P. Klaholz, Ali Hamiche CENP-A nucleosome clusters form rosette-like structures around HJURP during G1 published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-12383-3	Nature Communications 10/1	2020-03-05
2019	Erney RamÃrez-Aportela, Javier Mota, Pablo Conesa, Jose Maria Carazo, Carlos Oscar S. Sorzano DeepRes : a new deep-learning- and aspect-based local resolution method for electron-microscopy maps published pages: 1054-1063, ISSN: 2052-2525, DOI: 10.1107/s2052252519011692	IUCrJ 6/6	2020-03-05
2019	Uchanski T, Masiulis S, Fischer B, Kalichuk V, Wohlkonig A, Zogg T, Remaut H, Vranken W, Aricescu AR, Pardon E, Steyaert J. Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM. published pages: , ISSN: , DOI:	bioRxiv	2020-03-05
2019	Bruno P. Klaholz Deriving and refining atomic models in crystallography and cryo-EM: the latest Phenix tools to facilitate structure analysis published pages: 878-881, ISSN: 2059-7983, DOI: 10.1107/s2059798319013391	Acta Crystallographica Section D Structural Biology 75/10	2020-03-05
2019	Sanchez-Garcia R, Segura J, Maluenda D, Sorzano CO, Carazo JM. MicrographCleaner: a python package for cryo-EM micrograph segmentation using deep learning. published pages: , ISSN: , DOI:	bioRxiv	2020-03-05
2018	Maryam Faridounnia, Gert Folkers, Rolf Boelens Function and Interactions of ERCC1-XPF in DNA Damage Response published pages: 3205, ISSN: 1420-3049, DOI: 10.3390/molecules23123205	Molecules 23/12	2020-03-05
2018	Amaya JimÃ©nez, Slavica Jonic, Tomas Majtner, JoaquÃn OtÃ³n, Jose Luis Vilas, David Maluenda, Javier Mota, Erney RamÃrez-Aportela, Marta MartÃnez, Yaiza Rancel, Joan Segura, Ruben SÃ¡nchez-GarcÃa, Roberto Melero, Laura del Cano, Pablo Conesa, Lars Skjaerven, Roberto Marabini, Jose M Carazo, Carlos Oscar S Sorzano Validation of electron microscopy initial models via small angle X-ray scattering curves published pages: 2427-2433, ISSN: 1367-4803, DOI: 10.1093/bioinformatics/bty985	Bioinformatics 35/14	2020-03-05
2019	Haitian Fan, Alexander P. Walker, LoÃ¯c Carrique, Jeremy R. Keown, Itziar Serna Martin, Dimple Karia, Jane Sharps, Narin Hengrung, Els Pardon, Jan Steyaert, Jonathan M. Grimes, Ervin Fodor Structures of influenza A virus RNA polymerase offer insight into viral genome replication published pages: 287-290, ISSN: 0028-0836, DOI: 10.1038/s41586-019-1530-7	Nature 573/7773	2020-03-05
2019	Linda Cerofolini, Stefano Giuntini, Letizia Barbieri, Matteo Pennestri, Anna Codina, Marco Fragai, Lucia Banci, Enrico Luchinat, Enrico Ravera Real-Time Insights into Biological Events: In-Cell Processes and Protein-Ligand Interactions published pages: 239-247, ISSN: 0006-3495, DOI: 10.1016/j.bpj.2018.11.3132	Biophysical Journal 116/2	2020-03-05
2019	D. Maluenda, T. Majtner, P. Horvath, J. L. Vilas, A. JimÃ©nez-Moreno, J. Mota, E. RamÃrez-Aportela, R. SÃ¡nchez-GarcÃa, P. Conesa, L. del CaÃ±o, Y. Rancel, Y. Fonseca, M. MartÃnez, G. Sharov, C.A. GarcÃa, D. Strelak, R. Melero, R. Marabini, J. M. Carazo, C. O. S. Sorzano Flexible workflows for on-the-fly electron-microscopy single-particle image processing using Scipion published pages: 882-894, ISSN: 2059-7983, DOI: 10.1107/s2059798319011860	Acta Crystallographica Section D Structural Biology 75/10	2020-03-05
2019	Tomasz UchaÅ„ski, Simonas Masiulis, Baptiste Fischer, Valentina Kalichuk, Alexandre WohlkÃ¶nig, Thomas ZÃ¶gg, Han Remaut, Wim Vranken, A. Radu Aricescu, Els Pardon, Jan Steyaert Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM published pages: , ISSN: , DOI: 10.1101/812230	bioRxiv	2020-02-06
2018	Ottilie von Loeffelholz, Gabor Papai, Radostin Danev, Alexander G. Myasnikov, S. Kundhavai Natchiar, Isabelle Hazemann, Jean-FranÃ§ois MÃ©nÃ©tret, Bruno P. Klaholz Volta phase plate data collection facilitates image processing and cryo-EM structure determination published pages: 191-199, ISSN: 1047-8477, DOI: 10.1016/j.jsb.2018.01.003	Journal of Structural Biology 202/3	2019-06-12
2017	S. Kundhavai Natchiar, Alexander G. Myasnikov, Hanna Kratzat, Isabelle Hazemann, Bruno P. Klaholz Visualization of chemical modifications in the human 80S ribosome structure published pages: , ISSN: 0028-0836, DOI: 10.1038/nature24482	Nature	2019-06-12
2018	Thomas Vosegaard Fast simulations of multidimensional NMR spectra of proteins and peptides published pages: 438-448, ISSN: 0749-1581, DOI: 10.1002/mrc.4663	Magnetic Resonance in Chemistry 56/6	2019-06-12

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