#	Pagina
attuale pagina	/open-h2020/projects/207687/index.html
-1	/open-h2020/projects/202620/index.html

Opendata, web and dolomites

SMILE

Synchrotron Miniaturization enabling Innovative Laboratory Equipment in soft x-ray tomography.

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

SMILE project word cloud

Explore the words cloud of the SMILE project. It provides you a very rough idea of what is the project "SMILE" about.

contrast microscope commercial researcher generating discovery approx cells technologies 15 global restricted locations 000m2 synchrotron delivered miniaturizing images spend cell regulatory microscopes business size moving model siriusxt daily disease 500m queue predicted fold ray pilots subcellular assembly smile electron 200 months progression suitable source sxt100 area therapy carry exists market reducing 3d six soft million internal addressable few optical cures biological gives drug healthcare relates disruptive imaging productivity near labs innovation world image resolution prototype structure ease 3m2 customer serviceability annually manufacturing hours natural 500

Project "SMILE" data sheet

The following table provides information about the project.

Coordinator	SIRIUSXT LIMITED Organization address address: SUITTE 133, SCIENCE CENTRE NORTH, BELFIELD city: DUBLIN postcode: 4 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Project website	http://www.siriusxt.com
Total cost	3˙000˙935 €
EC max contribution	3˙000˙935 € (100%)
Programme	1. H2020-EU.3.1.3. (Treating and managing disease)
Code Call	H2020-SMEINST-2-2016-2017
Funding Scheme	SME-2
Starting year	2017
Duration (year-month-day)	from 2017-01-01 to 2019-02-28

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	SIRIUSXT LIMITED SIRIUSXT LIMITED Organization address address: SUITTE 133, SCIENCE CENTRE NORTH, BELFIELD city: DUBLIN postcode: 4 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	coordinator	3˙000˙935.00

Map

Project objective

The aim of SMILE is to support SiriusXT in moving a prototype of its soft x-ray microscope (SXT100) from prototype to commercial product through addressing ease-of-assembly, manufacturing scale-up, serviceability, customer pilots, regulatory pathways and business model requirements. The disruptive innovation delivered by SMILE is to open up the market for soft x-ray imaging from approx. 100 users today to an immediate target addressable market of over 3,000 disease research and drug discovery organisations by reducing the cost of the microscope assembly by a factor of over 200 (from over €500 million to €2.5 million) and miniaturizing its size, by a factor of 5,000 (from 15,000m2 area to approx. 3m2). Soft x-ray imaging is the only means available today of generating high resolution, high contrast, 3D images of the internal structure of whole biological cells in their near-natural state. Cell researchers currently spend approx. €500m annually on electron and optical microscopes in order to increase their understanding of subcellular structure and how this relates to disease progression and therapy, however neither of these technologies is capable of imaging the whole internal cell structure. The SXT100 gives disease research and drug discovery organisations daily access to a soft x-ray microscope in their own labs, rather than having to queue for often more than six months to get a few hours of access to one of only four synchrotron locations around the world where a suitable soft x-ray source and microscope exists today. The SXT100 will not only increase a researcher’s productivity 100-fold, in the number of biological cells they can image, but it also allows them to carry out a range of disease progression studies, not possible today because of the restricted access to these synchrotron microscopes. SMILE is predicted to have a significant impact in addressing the EU/global challenge in reducing the cost of healthcare delivery and developing cures for disease.

Deliverables

List of deliverables.
D3.3: Demo Inline Fluorescence Microscope	Demonstrators, pilots, prototypes	2019-09-09 12:57:49
D3.2: Demo Sample Holder	Demonstrators, pilots, prototypes	2019-09-09 12:57:49
D7.5 PR	Websites, patent fillings, videos etc.	2019-09-09 12:57:49
D2.4: Assembly & Test	Demonstrators, pilots, prototypes	2019-09-09 12:57:49
D7.3: Website	Websites, patent fillings, videos etc.	2019-09-09 12:57:49

Take a look to the deliverables list in detail: detailed list of SMILE deliverables.

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "SMILE" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "SMILE" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.3.1.3.)

DIAdIC (2019)

Evaluation of Dyadic Psychoeducational Interventions for People with Advanced Cancer and their Informal Caregivers (DIAdIC): An international randomized controlled trial

GACD (2019)

Global Alliance for Chronic Diseases Secretariat

ESCALON (2019)

European-Latin American network for the assessment of biomarkers to predict and diagnose hepatobiliary malignancies and characterization of risk factors for cancer development