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ImmunoGrow

Making life-saving cancer therapies more widely available by simplifying production processes, reducing costs and enhancing patient safety through its patent-protected biomimicking mesh material.

Total Cost €

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EC-Contrib. €

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Partnership

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 ImmunoGrow project word cloud

Explore the words cloud of the ImmunoGrow project. It provides you a very rough idea of what is the project "ImmunoGrow" about.

safer    fund    costly    achieves    83    treatment    reducing    cell    performance    save    treatments    therapies    feasibility    body    yield    helps    mesh    customers    harness    protected    patent    core    shown    significantly    life    untreatable    manufacture    limited    2019    trials    2021    variability    changing    infrastructure    engineered    standard    release    reduce    mimics    car    initial    expensive    rates    dynabeads    poor    produces    manufacturers    individualised    seeking    cancers    15    cells    solutions    limitations    seed    immunogrow    lab    500    encounter    patients    anticipated    activation    2030    natural    gmt    automated    prices    closed    publically    simplifying    independent    citizens    gold    grey    requirement    patient    sickest    remission    475    8x    business    ltd    lifesaving    aggressive    skilled    round    immune    cleanroom    ing    consumables    operator    cheaper    technologies    expects    healthcare    labour    tests    input    genetically    prohibitive    q3    full    addressable    struggling    structure    capture    unless    priced    cancer    market    plan    conduct    600mn   

Project "ImmunoGrow" data sheet

The following table provides information about the project.

Coordinator
Grey Matter Technologies Limited 

Organization address
address: MERTON BREE ENNISCORTHY
city: WEXFORD
postcode: Y21 Y5V0
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Ireland [IE]
 Project website http://www.immunogrow.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2019
 Duration (year-month-day) from 2019-08-01   to  2019-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    Grey Matter Technologies Limited IE (WEXFORD) coordinator 50˙000.00

Map

 Project objective

Lifesaving cell-based CAR-T therapies have achieved remission rates of up to 83% for patients with the most aggressive and untreatable cancers. These therapies harness a patient’s own genetically engineered immune cells to target cancer cells. However, manufacturers are struggling to produce these individualised treatments at scale resulting in prohibitive prices as high as $475,000 per treatment. Unless solutions that address these limitations are provided, publically-funded EU healthcare systems & citizens will be priced out of these life-changing therapies.

The challenges they face include poor cell growth performance due to patient sample variability, limitations associated with equipment adopted from the research lab that require costly skilled labour, costly consumables and expensive cleanroom infrastructure.

Compared to the gold standard, Dynabeads, initial testing has shown that the ImmunoGrow technology produces an 8x higher cell yield which helps to save the sickest patients who have limited cells and significantly reduce the cost to manufacture these therapies by simplifying the process, reducing the requirement for skilled operator input and making this step both ‘closed’ and automated. ImmunoGrow achieves this through its patent-protected mesh structure that mimics the natural growth conditions cells encounter in the body.

Grey Matter Technologies (‘GMT’) Ltd. is seeking support to help fund trials with two identified customers as well to help it to conduct an independent set of tests on the product’s performance. Both these trials, as well as an associated business plan or feasibility study, will be core to the raising of a seed round of €500,000 in 2019 to further develop the technology with the release of a full-scale product anticipated for Q3 2021. GMT expects to capture 15% of the $600mn addressable T-Cell Activation market in 2030. In doing so, it will make these life changing treatments cheaper, safer and more widely available.

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The information about "IMMUNOGROW" are provided by the European Opendata Portal: CORDIS opendata.

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