NGS kits and reagents compatible with NextSeq 550 dx (with and without funding from the Ministry of Health for the Program for the Application of Precision Medicine in the Treatment of Malignant Disea

contract notice

Following the summary about the notice 2024/S 002-002797 dispatched in the year 2024.


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Contracting authority Macedonian Academy of Sciences and Arts 1 info
Северна Македонија / Severna Makedonija (MK) more authorities
Type of the contracting authority Regional or local authority
Main activity Education
Type of contract Supplies
Main CPV code
Place of performance Северна Македонија / Severna Makedonija (MK) more
Country EN; - country: MK
Document type Contract notice
Procedure Open procedure
Type of bid Submission for all lots
Award criteria Lowest price
Regulation Other
Publication date 2024-01-03 00:00:00
Deadline 2024-01-29 00:00:00

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Section I: Contracting authority

I.1) Name and addresses please identify all contracting authorities responsible for the procedure

Official name
Macedonian Academy of Sciences and Arts
Postal address
bul. Krste Misirkov no. 2 Skopje
Postal code: 1000
NUTS code: n.d. tipo 1 N.D. (n.d. tipo 1)
Country
Macedonia, The Former Yugoslav Republic of (MK)
Contact person
Sanja Kiprjanovska Telephone: n.d. E-mail: skiprijanovska@manu.edu.mk Fax: n.d.
Internet address(es)
Main address: https://manu.edu.mk/
Address of the buyer profile: n.d.

I.4) Type of the contracting authority

Regional or local authority

I.5) Main activity

Education

Section II: Object

II.1) Scope of the procurement

  • II.1.1) Title

    NGS kits and reagents compatible with NextSeq 550 dx (with and without funding from the Ministry of Health for the Program for the Application of Precision Medicine in the Treatment of Malignant Disea (Reference number 23862/2023)

  • II.1.2) Main CPV code

    33000000 Medical equipments, pharmaceuticals and personal care products

  • II.1.3) Type of contract

    Supplies

  • II.1.4) Short description

    NGS kits and reagents compatible with NextSeq 550 dx (with and without funding from the Ministry of Health for the Program for the Application of Precision Medicine in the Treatment of Malignant Disea

  • II.1.6) Information about lots

    This contract is divided into lots

    yes

    Tenders may be submitted for all lots

II.2) Description

II.2.1) Title: Sequencing panel through specialized oligo-target regions of interest, which includes a minimum of 94 target genes and 284 SNPs associated with cancer predisposition. [Lot No: [1]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

Sequencing panel through specialized oligo-target regions of interest, which includes a minimum of 94 target genes and 284 SNPs associated with cancer predisposition. Panel to include kit of reagents, library and 96 sample sequencing cartridges with included cartridges for a minimum of 4 analyzes of 24 samples at a time compatible with Illumina MiSeq sequencer, or equivalent

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: A pre-designed and ready-to-use panel for sequencing through specialized oligo-target regions of interest, including a minimum of 94 target genes and 284 SNPs with 4000 probes of interest associated [Lot No: [2]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

A pre-designed and ready-to-use panel for sequencing through specialized oligo-target regions of interest, including a minimum of 94 target genes and 284 SNPs with 4000 probes of interest associated with a predisposition to cancers, sufficient for 8 enrichment reactions and 96 samples, compatible for MiSeq sequencer IIllumina or equivalent. TruSight Cancer Gene Set or equivalent

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: 96 dual indexes of size 10 nucleotide bases each with pre-prepared combinations of the i5 and i7 ends, pre-prepared on a 96-position board and ready to use. [Lot No: [3]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

96 dual indexes of size 10 nucleotide bases each with pre-prepared combinations of the i5 and i7 ends, pre-prepared on a 96-position board and ready to use. Each well on the plate should have a unique combination. Indexes Set A, Tagmentation, or equivalent.

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: Kit for preparing a target-sequencing library from shrekku tagmentation samples for DNA fragmentation and adapter addition. [Lot No: [4]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

Kit for preparing a target-sequencing library from shrekku tagmentation samples for DNA fragmentation and adapter addition. This kit should allow the preparation of enrichment-based sequencing of 96 samples, This kit should be suitable for the MiSeq personal sequencer and compatible with the offered parts 1,2,3 and 4. Ilumina DNA Prep enrichment panel or equivalent

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: A ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer. MiSeq Reagent Kit V2 (300 cycles), or equivalent [Lot No: [5]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

A ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer. MiSeq Reagent Kit V2 (300 cycles), or equivalent

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: Ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer, capable of 4 million reads per cell MiSeq Reagent mikro Kit V2 [Lot No: [6]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

Ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer, capable of 4 million reads per cell MiSeq Reagent mikro Kit V2 (300 cycles), or equivalent

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 400 million fragments in parallel [Lot No: [7]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 400 million fragments in parallel per cell. NextSeq 500/550 High Output Kit v2.5 (300 Cycles), or equivalent.

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 130 million fragments in parallel [Lot No: [8]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 130 million fragments in parallel per cell. NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles), or equivalent.

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: A panel of oligonucleotide probes for enrichment of nucleotide sequences of interest. The samples are intended for sequencing of the complete human exome (Whole Exome Sequencing, WES). [Lot No: [9]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

A panel of oligonucleotide probes for enrichment of nucleotide sequences of interest. The samples are intended for sequencing of the complete human exome (Whole Exome Sequencing, WES). This kit is compatible with the Ilumina DNA Prep enrichment kit. This kit should enable the preparation of enrichment-based sequencing sufficient for 8 enrichment reactions of 12 samples each, i.e. for a total of 96 samples. Illumina Exome Panel – Enrichment Oligos Only, or equivalent.

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

II.2.1) Title: An oncology panel that includes a complete set of NGS sequencing reagents for at least 24 DNA and/or RNA samples obtained from paraffin-embedded tissues. [Lot No: [10]]

II.2.2) Additional CPV code(s)

Main CPV code

33000000 | Medical equipments, pharmaceuticals and personal care products

II.2.4) Description of the procurement

An oncology panel that includes a complete set of NGS sequencing reagents for at least 24 DNA and/or RNA samples obtained from paraffin-embedded tissues. The panel should enable the detection of at least 500 genes from DNA, and at least 50 genes from RNA associated with prognosis and/or prediction of response to therapy in various malignant diseases.

II.2.5) Award criteria

Price

II.2.7) Duration of the contract, framework agreement or dynamic purchasing system

Duration in months: 12

This contract is subject to renewal: no

II.2.10) Information about variants

Variants will be accepted: no

II.2.11) Information about options

Options: no

Section III: Legal, economic, financial and technical information

No info

Section IV: Procedure

IV.1) Description

IV.1.1) Type of procedure

Open procedure

IV.1.8) Information about the Government Procurement Agreement (GPA)

The procurement is covered by the Government Procurement Agreement: no

IV.2) Administrative information

IV.2.2) Time limit for receipt of tenders or requests to participate

Date (dd/mm/yyyy): 2024-01-29

Local time (hh:mm): 10:00

IV.2.4) Languages in which tenders or requests to participate may be submitted

  • MK

IV.2.7) Conditions for opening of tenders

Date (dd/mm/yyyy): 2024-01-29

Local time (hh:mm): 10:00

Section VI: Complementary information

VI.1) Information about recurrence

This is a recurrent procurement: no

VI.4) Procedures for review

VI.4.1) Review body

Official name
Macedonian Academy of Sciences and Arts [n.d.]
Postal address
bul. Krste Misirkov no. 2 Skopje 1000 - nuts: n.d. tipo 1
Country
MK
Contact person
Sanja Kiprjanovska Telephone: n.d. E-mail: skiprijanovska@manu.edu.mk Fax: n.d.
Internet address(es)
Main address: https://manu.edu.mk/ | Address of the buyer profile: n.d.

Date of dispatch of this notice

Date of dispatch of this notice (dd/mm/yyyy): 2023-12-29

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5 AC_PRICE

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5 P: 96 dual indexes of size 10 nucleotide bases each with pre-prepared combinations of the i5 and i7 ends, pre-prepared on a 96-position board and ready to use.

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5 P: 96 dual indexes of size 10 nucleotide bases each with pre-prepared combinations of the i5 and i7 ends, pre-prepared on a 96-position board and ready to use. Each well on the plate should have a unique combination. Indexes Set A, Tagmentation, or equivalent.

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: Kit for preparing a target-sequencing library from shrekku tagmentation samples for DNA fragmentation and adapter addition.

L: 4 --- key: (LOT_NO)   value: 4

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: Kit for preparing a target-sequencing library from shrekku tagmentation samples for DNA fragmentation and adapter addition. This kit should allow the preparation of enrichment-based sequencing of 96 samples, This kit should be suitable for the MiSeq personal sequencer and compatible with the offered parts 1,2,3 and 4. Ilumina DNA Prep enrichment panel or equivalent

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: A ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer. MiSeq Reagent Kit V2 (300 cycles), or equivalent

L: 4 --- key: (LOT_NO)   value: 5

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: A ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer. MiSeq Reagent Kit V2 (300 cycles), or equivalent

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: Ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer, capable of 4 million reads per cell MiSeq Reagent mikro Kit V2

L: 4 --- key: (LOT_NO)   value: 6

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: Ready-to-use cartridge with a capacity of 300 cycles, compatible with Illumina sequencing panels on the MiSeq personal sequencer, capable of 4 million reads per cell MiSeq Reagent mikro Kit V2 (300 cycles), or equivalent

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 400 million fragments in parallel

L: 4 --- key: (LOT_NO)   value: 7

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 400 million fragments in parallel per cell. NextSeq 500/550 High Output Kit v2.5 (300 Cycles), or equivalent.

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 130 million fragments in parallel

L: 4 --- key: (LOT_NO)   value: 8

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: A ready-to-use 300-cycle capacity cartridge compatible with Illumina sequencing panels on the NextSeq550dx personal sequencer or equivalent capable of reading up to 130 million fragments in parallel per cell. NextSeq 500/550 Mid Output Kit v2.5 (300 Cycles), or equivalent.

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: A panel of oligonucleotide probes for enrichment of nucleotide sequences of interest. The samples are intended for sequencing of the complete human exome (Whole Exome Sequencing, WES).

L: 4 --- key: (LOT_NO)   value: 9

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: A panel of oligonucleotide probes for enrichment of nucleotide sequences of interest. The samples are intended for sequencing of the complete human exome (Whole Exome Sequencing, WES). This kit is compatible with the Ilumina DNA Prep enrichment kit. This kit should enable the preparation of enrichment-based sequencing sufficient for 8 enrichment reactions of 12 samples each, i.e. for a total of 96 samples. Illumina Exome Panel – Enrichment Oligos Only, or equivalent.

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

3 OBJECT_DESCR

4 TITLE

5 P: An oncology panel that includes a complete set of NGS sequencing reagents for at least 24 DNA and/or RNA samples obtained from paraffin-embedded tissues.

L: 4 --- key: (LOT_NO)   value: 10

4 CPV_ADDITIONAL

5 CPV_CODE

4 SHORT_DESCR

5 P: An oncology panel that includes a complete set of NGS sequencing reagents for at least 24 DNA and/or RNA samples obtained from paraffin-embedded tissues. The panel should enable the detection of at least 500 genes from DNA, and at least 50 genes from RNA associated with prognosis and/or prediction of response to therapy in various malignant diseases.

4 AC

5 AC_PRICE

L: 4 --- key: (DURATION)   value: 12

4 NO_RENEWAL

4 NO_ACCEPTED_VARIANTS

4 NO_OPTIONS

4 NO_EU_PROGR_RELATED

2 PROCEDURE

3 PT_OPEN

3 NO_CONTRACT_COVERED_GPA

3 --- DATE_RECEIPT_TENDERS   value: 2024-01-29

3 --- TIME_RECEIPT_TENDERS   value: 10:00

3 LANGUAGES

INFO4: MK

4 LANGUAGE

3 OPENING_CONDITION

L: 4 --- key: (DATE_OPENING_TENDERS)   value: 2024-01-29

L: 4 --- key: (TIME_OPENING_TENDERS)   value: 10:00

2 COMPLEMENTARY_INFO

3 NO_RECURRENT_PROCUREMENT

3 ADDRESS_REVIEW_BODY

L: 4 --- key: (OFFICIALNAME)   value: State Commission for Public Procurement Appeals

L: 4 --- key: (TOWN)   value: Skopje

INFO4: MK

4 COUNTRY

3 --- DATE_DISPATCH_NOTICE   value: 2023-12-29

20+1