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ZEBRAONCOFISH SIGNED

Zebrafish avatar as a real-time in vivo platform for personalized cancer therapeutics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ZEBRAONCOFISH project word cloud

Explore the words cloud of the ZEBRAONCOFISH project. It provides you a very rough idea of what is the project "ZEBRAONCOFISH" about.

cell    xenotransplantation    individual    carry    made    effect    market    tubes    estimations    solutions    leader    onset    performed    makeup    deaths    interspecies    time    healthcare    influence    found    biology    biotechnological    lab    platform    genetic    zebrafish    drugs    personalized    differently    samples    extensive    morbidity    interventions    complexity    people    living    disease    created    vivo    treatment    biological    human    presented    dynamic    actionable    cancer    profile    mean    company    therapeutic    therapy    thanks    remarkable    425    transplant    display    mechanism    metabolic    understand    ultimate    directed    tailor    difficulty    tumor    tax    hospitals    patient    zebraoncofish    close    acquired    guide    chance    mortality    commercialization    complete    million    team    progression    solution    subjacent    anticancer    35    underlying    avatars    opportunity    approx    lines    cancerous    roadmap    treatments    decisions    assays   

Project "ZEBRAONCOFISH" data sheet

The following table provides information about the project.

Coordinator
IKAN BIOTECH S.L. 

Organization address
address: CALLE CHAPITELA 20 1
city: PAMPLONA
postcode: 31001
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://zebraoncofish.com/
 Total cost 2˙004˙583 €
 EC max contribution 2˙004˙583 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IKAN BIOTECH S.L. ES (PAMPLONA) coordinator 2˙004˙583.00

Map

 Project objective

The Zebrafish Lab is a biotechnological company leader in the development and commercialization of novel, tailor-made solutions based on in vivo zebrafish assays. Thanks to the extensive knowledge acquired by the R&D projects performed in the field by our team for many years and a close collaboration with Hospitals and Cancer Research Institutions, we have identified a remarkable opportunity in the ZEBRAONCOFISH project that will mean a 5-year after tax-R.O.I of 425% according to our estimations. The ultimate goal of the project presented as ZEBRAONCOFISH is to complete the technical roadmap required to bring to the healthcare market a novel real time in vivo platform for personalized cancer treatment based on the use of zebrafish “avatars” as personalized, living test tubes. Cancer is a leading cause of morbidity and mortality with approx. 35 million people affected by this disease and more than 8 million deaths per year. A major difficulty found in effective cancer treatment is the complexity of the biological mechanism underlying cancer onset and disease progression. This is because the genetic makeup and metabolic profile of each individual patient influence the effect of anticancer drugs. As such, different people respond differently to the same therapy. The solution we propose in the ZEBRAONCOFISH project is the use of zebrafish avatars as an in vivo platform to guide therapeutic decisions in actionable cancer patient-directed interventions. These avatars will be created by xenotransplantation (interspecies transplant) of human cancer cell lines/ tumor samples in zebrafish. The chance to carry out a dynamic display of the cancerous process in vivo will offer the unique opportunity to understand the subjacent cancer biology and design tailor-made treatments for each patient.

 Deliverables

List of deliverables.
ZEBRAONCOFISH webpage Websites, patent fillings, videos etc. 2020-04-24 04:18:30

Take a look to the deliverables list in detail:  detailed list of ZEBRAONCOFISH deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Letrado P, de Miguel I, Lamberto I, Díez-Martínez R, Oyarzabal J.
Zebrafish: Speeding up the Cancer Drug Discovery Process.
published pages: , ISSN: 0008-5472, DOI:
Cancer Research 2020-04-24

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The information about "ZEBRAONCOFISH" are provided by the European Opendata Portal: CORDIS opendata.

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