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ZEBRAONCOFISH SIGNED

Zebrafish avatar as a real-time in vivo platform for personalized cancer therapeutics

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 ZEBRAONCOFISH project word cloud

Explore the words cloud of the ZEBRAONCOFISH project. It provides you a very rough idea of what is the project "ZEBRAONCOFISH" about.

35    zebraoncofish    underlying    drugs    therapeutic    hospitals    estimations    understand    patient    vivo    company    anticancer    million    roadmap    avatars    mechanism    ultimate    team    genetic    425    created    morbidity    tubes    transplant    progression    difficulty    treatments    mean    makeup    interventions    solution    treatment    carry    platform    display    cell    differently    guide    influence    market    mortality    living    disease    human    zebrafish    opportunity    therapy    personalized    samples    found    biology    biological    lab    solutions    tax    people    subjacent    profile    xenotransplantation    cancer    close    chance    biotechnological    effect    tailor    approx    deaths    healthcare    individual    extensive    complexity    metabolic    performed    onset    acquired    time    actionable    thanks    dynamic    leader    directed    interspecies    complete    tumor    assays    made    presented    cancerous    lines    commercialization    remarkable    decisions   

Project "ZEBRAONCOFISH" data sheet

The following table provides information about the project.

Coordinator
IKAN BIOTECH S.L. 

Organization address
address: CALLE CHAPITELA 20 1
city: PAMPLONA
postcode: 31001
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Spain [ES]
 Project website http://zebraoncofish.com/
 Total cost 2˙004˙583 €
 EC max contribution 2˙004˙583 € (100%)
 Programme 1. H2020-EU.3.1.3. (Treating and managing disease)
 Code Call H2020-SMEINST-2-2016-2017
 Funding Scheme SME-2
 Starting year 2017
 Duration (year-month-day) from 2017-09-01   to  2020-05-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    IKAN BIOTECH S.L. ES (PAMPLONA) coordinator 2˙004˙583.00

Map

 Project objective

The Zebrafish Lab is a biotechnological company leader in the development and commercialization of novel, tailor-made solutions based on in vivo zebrafish assays. Thanks to the extensive knowledge acquired by the R&D projects performed in the field by our team for many years and a close collaboration with Hospitals and Cancer Research Institutions, we have identified a remarkable opportunity in the ZEBRAONCOFISH project that will mean a 5-year after tax-R.O.I of 425% according to our estimations. The ultimate goal of the project presented as ZEBRAONCOFISH is to complete the technical roadmap required to bring to the healthcare market a novel real time in vivo platform for personalized cancer treatment based on the use of zebrafish “avatars” as personalized, living test tubes. Cancer is a leading cause of morbidity and mortality with approx. 35 million people affected by this disease and more than 8 million deaths per year. A major difficulty found in effective cancer treatment is the complexity of the biological mechanism underlying cancer onset and disease progression. This is because the genetic makeup and metabolic profile of each individual patient influence the effect of anticancer drugs. As such, different people respond differently to the same therapy. The solution we propose in the ZEBRAONCOFISH project is the use of zebrafish avatars as an in vivo platform to guide therapeutic decisions in actionable cancer patient-directed interventions. These avatars will be created by xenotransplantation (interspecies transplant) of human cancer cell lines/ tumor samples in zebrafish. The chance to carry out a dynamic display of the cancerous process in vivo will offer the unique opportunity to understand the subjacent cancer biology and design tailor-made treatments for each patient.

 Deliverables

List of deliverables.
ZEBRAONCOFISH webpage Websites, patent fillings, videos etc. 2020-04-24 04:18:30

Take a look to the deliverables list in detail:  detailed list of ZEBRAONCOFISH deliverables.

 Publications

year authors and title journal last update
List of publications.
2018 Letrado P, de Miguel I, Lamberto I, Díez-Martínez R, Oyarzabal J.
Zebrafish: Speeding up the Cancer Drug Discovery Process.
published pages: , ISSN: 0008-5472, DOI:
Cancer Research 2020-04-24

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The information about "ZEBRAONCOFISH" are provided by the European Opendata Portal: CORDIS opendata.

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