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BioREAD
BioREAD; a Continuous Barrier Quality Monitoring System for Organs-on-Chip
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0BioREAD project word cloud
Explore the words cloud of the BioREAD project. It provides you a very rough idea of what is the project "BioREAD" about.
gut
stem
cell
differentiated
holds
journal
instrument
excellent
doses
medicine
resistance
engineering
teer
barrier
person
cosmetics
innovation
versatile
drug
inaccurate
harmful
safety
15
discontinuous
2015
tests
animal
chips
chip
organ
monitoring
vascular
disadvantages
direct
bios
endothelial
pharmaceutical
blood
erc
vescel
dc
cited
food
brain
apparatus
quality
play
serve
function
effectiveness
overcomes
electrical
unsuitable
fluorescence
lab
trans
organs
combined
besides
detector
commercially
safe
group
demonstrating
promise
compounds
papers
record
industry
screening
ample
guarantee
commercialization
individual
cells
hold
outcomes
personalized
diseases
continuous
Project "BioREAD" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITEIT TWENTE
Organization address contact info |
| Coordinator Country | Netherlands [NL] |
| Total cost | 150˙000 € |
| EC max contribution | 150˙000 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2016-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-01-01 to 2018-06-30 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITEIT TWENTE | NL (ENSCHEDE) | coordinator | 150˙000.00 |
Map
Project objective
Organs-on-chip are expected to play a crucial role in the pharmaceutical industry for drug development and study of organs and diseases. We propose the development of an electrical detector that enables simple, versatile and continuous quality monitoring of these devices and is essential for commercialization. Combined with recent advances in stem cell technology, Organ-on-Chips can be used to do drug screening on an individual level. Therefore it can serve as instrument for personalized medicine, by determining the effectiveness of selected compounds, as well as possible side-effects to determine safe drug doses on a person-specific level. Moreover, Organs-on-Chip will greatly contribute to a further reduction in the need for animal testing. Besides the pharmaceutical industry, Organs-on-Chip hold great promise for the food and cosmetics industry to test the safety of products.
Organ-on-Chip systems need continuous monitoring of the quality of the cell barrier to guarantee reliable outcomes of the drug development tests. State-of-the-art methods, such as fluorescence and commercially available Trans-Endothelial Electrical Resistance (TEER) measurement apparatus are discontinuous, inaccurate and/or harmful for the cells and therefore unsuitable for pharmaceutical applications. Our innovation overcomes these disadvantages. It enables continuous quality monitoring of the barrier function of the organ, which is essential for the commercialization of Organs-on-Chip. The BIOS-Lab on Chip group holds an excellent record in high-quality TEER measurements, demonstrating direct current (DC) TEER-measurements in a gut-on-a-chip in a top-15 of most cited research papers in the journal Lab-on-Chip in 2015 and has ample experience in the development of a blood-brain barrier on chip. This proposal is part of the ERC-project Vascular Engineering on-chip using differentiated Stem Cells (VESCEL).
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For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "BIOREAD" are provided by the European Opendata Portal: CORDIS opendata.
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No valid XML
lastchecktime (2024-08-14 23:04:49) correctly updated