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CITYCARE SIGNED

Impact of air pollutants on cutaneous responses in both healthy and compromised skin barrier, and innovative solutions to protect skin against urban pollution

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

CITYCARE project word cloud

Explore the words cloud of the CITYCARE project. It provides you a very rough idea of what is the project "CITYCARE" about.

climatic compounds anthropic eid environment radiation nowadays pollutants location cellular psoriasis transferable domains uof career healthy fuel curative polymeric complexity film complementary atopic synergistic air barrier diesel individuals preventive stress smoke conditioning dermatitis environmental exhaust surface protect dce discovering antioxidant critical background cigarette stage aggressors optimization training natural molecular solutions efficacy uv extreme combining damaged assaulted weather gasoline expertise pollution origin skills exposed skin innovative stressors polymer biochemistry diseases expand suffering integrity biology ozone good unifr variety compromised living formulation function networking

Project "CITYCARE" data sheet

The following table provides information about the project.

Coordinator	DOW SILICONES BELGIUM Organization address address: RUE JULES BORDET PARC INDUSTRIEL ZONE C city: SENEFFE postcode: 7180 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Belgium [BE]
Project website	http://www.citycare-itn.eu
Total cost	773˙848 €
EC max contribution	773˙848 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2017
Funding Scheme	MSCA-ITN-EID
Starting year	2017
Duration (year-month-day)	from 2017-09-01 to 2021-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	DOW SILICONES BELGIUM DOW SILICONES BELGIUM Organization address address: RUE JULES BORDET PARC INDUSTRIEL ZONE C city: SENEFFE postcode: 7180 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (SENEFFE)	coordinator	250˙560.00
2	UNIVERSITE DE FRIBOURG UNIVERSITE DE FRIBOURG Organization address address: AVENUE DE L EUROPE 20 city: FRIBOURG postcode: 1700 website: www.unifr.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (FRIBOURG)	participant	265˙226.00
3	UNIVERSITA DEGLI STUDI DI FERRARA UNIVERSITA DEGLI STUDI DI FERRARA Organization address address: VIA ARIOSTO 35 city: FERRARA postcode: 44121 website: www.unife.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (FERRARA)	participant	258˙061.00
4	BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY Organization address address: SERRA MALL 450 city: STANFORD postcode: 94305 2004 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (STANFORD)	partner	0.00

Map

Project objective

Nowadays, our skin is increasingly more assaulted, as a result of the increasingly complexity of our living environment. Because of its critical location, the skin is continuously exposed not only to natural environmental stress factors, such as UV radiation, ozone and extreme weather conditions associated with climatic changes, but also to pollutants/aggressors of anthropic origin, such as cigarette smoke and diesel/gasoline fuel exhaust. By combining the complementary expertise of the three partners involved in the present consortium, i.e. polymer technology and formulation expertise (DCE), skin barrier understanding and biochemistry/molecular biology (UoF), and impact of diesel/gasoline exhaust on cellular responses (UNIFR), this project will aim (i) at better understanding the consequences of air pollutants on both skin integrity and function, (ii) at investigating the synergistic effects of air pollutants such as ozone, cigarette smoke and diesel exhaust with UV radiation, (iii) at discovering innovative solutions to protect skin against those environmental stressors using both a curative approach based on the optimization of the delivery and efficacy of antioxidant compounds, and a preventive approach, based on the formation of a polymeric barrier film at the skin surface, (iv) at studying the impact of air pollutants on both healthy skin and compromised, damaged skin since the number of individuals suffering from skin diseases such as atopic dermatitis and psoriasis continuously increases with the increasingly level of air pollution and air-conditioning systems. The variety of training offered under this EID proposal will enable three early-stage researchers to build strong S&T background as well as to develop numerous transferable skills for their future career. The present training program will allow the researchers to expand their knowledge to new domains and applications, while also providing good networking opportunities.

Deliverables

List of deliverables.
\"Scientific publication ESR2 #1\"	Other	2020-01-14 11:45:07
Inflammatory markers induced by ozone	Documents, reports	2020-01-14 11:42:38
Impact of cigarette smoke in combination with UV radiation on cutaneous responses in both healthy and atopic skin models	Documents, reports	2020-01-14 11:51:55
Advertisement of ESR position (including EURAXESS)	Other	2020-01-14 11:45:05
inflammatory markers induced by cigarette smoke	Documents, reports	2020-01-14 11:45:06
Cell culture models for assessing the toxicity induced by ozone	Documents, reports	2020-01-14 11:45:11
Workshop on Cell Culture & Molecular Biology	Other	2020-01-14 11:45:07
Impact of diesel/gasoline exhaust in combination with UV radiation on cutaneous responses in both healthy and atopic skin models	Documents, reports	2020-01-14 11:46:47
inflammatory markers induced by diesel/gasoline exhaust	Documents, reports	2020-01-14 11:42:37
Impact of ozone in combination with UV radiation on cutaneous responses in both healthy and atopic skin models	Documents, reports	2020-01-14 11:42:36
\"Scientific publication ESR3 #1\"	Other	2020-01-14 11:45:06
Cell culture models for assessing the toxicity induced by Cigarette smoke	Documents, reports	2020-01-14 11:45:07
Cell culture models for assessing the toxicity induced by Diesel Exhaust	Documents, reports	2020-01-14 11:42:37
\"Scientific publication ESR1 #1\"	Other	2020-01-14 11:45:06

Take a look to the deliverables list in detail: detailed list of CITYCARE deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Roxane Prieux, Marc Eeman, Barbara Rothen-Rutishauser, Giuseppe Valacchi Mimicking cigarette smoke exposure to assess cutaneous toxicity published pages: 104664, ISSN: 0887-2333, DOI: 10.1016/j.tiv.2019.104664	Toxicology in Vitro	2019-11-07
2019	Alessandra Pecorelli, Brittany Woodby, Roxane Prieux, Giuseppe Valacchi Involvement of 4â€hydroxyâ€2â€nonenal in pollutionâ€induced skin damage published pages: , ISSN: 0951-6433, DOI: 10.1002/biof.1513	BioFactors	2019-08-05

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The information about "CITYCARE" are provided by the European Opendata Portal: CORDIS opendata.