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BioIsoK SIGNED

Mechanisms of K stable isotope fractionation in vertebrates and significance to their energy metabolism

Total Cost €

EC-Contrib. €

Partnership

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BioIsoK project word cloud

Explore the words cloud of the BioIsoK project. It provides you a very rough idea of what is the project "BioIsoK" about.

class intensity biodiversity collision reaction technologies origins democratization functions metabolism icp tim later stable first body spectrometers fe ca varying cycling cell rates mg coupled inaccessible fisher mass cu principally unraveling unprecedented proteus fossil compositions group isotopes fairly advent plasma itself precious mechanisms metals reared ms natural traits assets bioessential physiological species otherwise reconstruction ecological isotope prototype mc potassium dynamics behavioral metal phylogenetic classes notably turned inherent biological ecosystems constitute evolution thermophysiology organisms reg opened tissues thermo ratios inductively vertebrate hindrances apprehending spectrometry dependent modern perspectives unexplored metabolic collector driving extinct zn elliott vertebrates energy

Project "BioIsoK" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITY OF BRISTOL Organization address address: BEACON HOUSE QUEENS ROAD city: BRISTOL postcode: BS8 1QU website: www.bristol.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Total cost	183˙454 €
EC max contribution	183˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2017
Funding Scheme	MSCA-IF-EF-ST
Starting year	2018
Duration (year-month-day)	from 2018-10-01 to 2020-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITY OF BRISTOL UNIVERSITY OF BRISTOL Organization address address: BEACON HOUSE QUEENS ROAD city: BRISTOL postcode: BS8 1QU website: www.bristol.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BRISTOL)	coordinator	183˙454.00

Map

Project objective

The reconstruction of physiological and ecological traits of extinct organisms is crucial for apprehending the dynamics of the evolution of species and ecosystems as well as the origins of modern biodiversity. The recent advent of the use of natural stable isotopes of bioessential metals is principally related to the democratization of multi-collector inductively coupled plasma mass spectrometers (MC-ICP-MS). These isotope systems (Mg, Ca, Cu, Fe or Zn) opened up unprecedented perspectives for the study of their cycling in past and present vertebrate organisms and turned out to be precious assets for the unraveling of otherwise inaccessible biological features of fossil organisms, being ecological, behavioral or physiological characteristics. Potassium (K) is a bioessential metal in all vertebrates, where its cycling intensity is notably dependent on their metabolic rates, the later varying itself with thermophysiology from a phylogenetic class to another or with body mass within a given class. Due to its crucial biological functions as well as the observed significant effects of biological processes on its isotope ratios, K isotopes constitute a highly promising novel isotope system for the study of vertebrate metabolism. However, the K stable isotope compositions of vertebrate tissues are currently fairly unexplored, notably due to major technical hindrances, inherent to the existing mass spectrometry technologies. This project aims first to develop a reliable method of K stable isotope analysis using the state-of-the-art “Proteus” prototype MC-ICP-MS implemented with the collision-reaction cell technology and developed by Tim Elliott group and Thermo Fisher®. This method will then be used for analysis of tissues from vertebrates of various classes reared in controlled conditions. This will allow identifying the main mechanisms driving the isotope compositions of vertebrate tissues and assess their potential for the study of vertebrates energy metabolism.

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The information about "BIOISOK" are provided by the European Opendata Portal: CORDIS opendata.