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Report

Teaser, summary, work performed and final results

Periodic Reporting for period 1 - ISOBAR (Cost Effective Personalised Compression Therapy for Chronic Venous Insufficiency with AccuratePressure Delivery for Comfort and Efficacy of Treatment)

Teaser

Summary

The ISOBAR concept is based on a novel approach of compression therapy delivery, which is essential for successful treatment and management of many common circulatory disorders (Chronic venous insufficiency, Lymphoedema and DVT prophylaxis). Chronic venous insufficiency (CVI) is a condition in which the blood, which normally would flow back to the heart from the veins in the lower limbs, does not do so efficiently because the valves in the veins are damaged or absent. It affects up to 50% of the adult population, and it is estimated that 1% of the UK population will suffer from leg ulceration during their lifetime. It is estimated that the annual cost of treatment for CVI in the European Union is â‚¬6.5 billion, and in the UK only the annual cost is up to â‚¬850 million.

Work performed

The ISOBAR technology is currently at TRL 7. After reviewing all of the information available on the vascular healthcare market, we have concluded that the European market, especially UK, France and Italy, will be the main focus for ISOBAR technology commercialization for the next 3 years. We have also evaluated potential partners for the software development (Imfusion GmbH, Germany). In addition, we identified ANR Manufacturing from Buckinghamshire, UK as a partner to assemble scanners from parts specified by ATM. We compiled a business plan, and as part of that, we created a risk analysis to help to form the basis for a Phase 2 application. ATM will therefore proceed with our plans to carry out the development project and submit a Phase 2 application to continue the route to commercialisation.

Final results

The ISOBAR technology will offer a novel approach of compression therapy delivery with a structured compression garment that fits a patient precisely and delivers the prescribed pressure. Once fully developed, it will resolve all the problems associated with the current techniques and systems for delivering compression therapies. The problems associated with the current methods: difficult applications and frequent measurement errors, constant supervision by trained clinicians required, numerous issues with therapy delivery, low pressure delivery and design problems, social isolation for the patients.