Explore the words cloud of the TASCMAR project. It provides you a very rough idea of what is the project "TASCMAR" about.
The following table provides information about the project.
Coordinator |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
Organization address contact info |
Coordinator Country | France [FR] |
Project website | http://www.tascmar.eu |
Total cost | 6˙758˙452 € |
EC max contribution | 6˙755˙950 € (100%) |
Programme |
1. H2020-EU.3.2. (SOCIETAL CHALLENGES - Food security, sustainable agriculture and forestry, marine, maritime and inland water research, and the bioeconomy) |
Code Call | H2020-BG-2014-2 |
Funding Scheme | RIA |
Starting year | 2015 |
Duration (year-month-day) | from 2015-04-01 to 2019-03-31 |
Take a look of project's partnership.
# | ||||
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1 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | FR (PARIS) | coordinator | 1˙442˙248.00 |
2 | ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON | EL (ATHINA) | participant | 801˙250.00 |
3 | CRELUX GMBH | DE (MARTINSRIED) | participant | 801˙212.00 |
4 | PIERRE GUERIN SAS | FR (NIORT) | participant | 800˙015.00 |
5 | TEL AVIV UNIVERSITY | IL (TEL AVIV) | participant | 400˙278.00 |
6 | UNIVERSITE DE LA REUNION | FR (SAINT DENIS DE LA REUNION CEDEX 9) | participant | 399˙917.00 |
7 | APIVITA KALLYNTIKA DIAITITIKA FARMAKA ANONYMI EMPORIKI KAI VIOTECHNIKI ETAIREIA | EL (MARKOPOULO) | participant | 399˙687.00 |
8 | ASSOCIATION ECO OCEAN | IL (TEL AVIV YAFFO) | participant | 349˙635.00 |
9 | BICT SRL | IT (LODI LO) | participant | 320˙875.00 |
10 | CHULALONGKORN UNIVERSITY | TH (BANGKOK) | participant | 299˙975.00 |
11 | IMARE NATURAL SL | ES (MOTRIL GRANADA) | participant | 299˙956.00 |
12 | ASTAREAL AB | SE (GUSTAVSBERG) | participant | 232˙900.00 |
13 | T6 ECOSYSTEMS SRL | IT (ROMA) | participant | 208˙000.00 |
TASCMAR project aspires to develop new tools and strategies in order to overcome existing bottlenecks in the biodiscovery and industrial exploitation of novel marine derived biomolecules (secondary metabolites and enzymes) with applications in the pharmaceuticals, nutraceuticals, cosmeceuticals and fine chemicals industries. Exploitation of neglected and underutilized marine invertebrates and symbionts from mesophotic zone will be combined with innovative approaches for the cultivation and extraction of marine organisms from lab to pilot-scale, using the unique prototypes Platotex™ and Zippertex™, both reaching the Technology Readiness Level 7. Thus, marine dedicated cultivation and extraction equipment will be built and validated. These unique improvements will ensure sustainable supply of biomass and promote the production of high added value bioactive marine compounds. An integrated, holistic technological metabolomic approach will be applied, in conjunction with bioactivity profiling, as filtering and bio-prioritisation tools. Moreover, state-of-the-art analytical instrumentation and in-house databases will be employed for the dereplication and characterization of valuable compounds. A panel of libraries (marine organisms, extracts, pure metabolites and biocatalysts) will be constructed and exploited throughout the project. A focused panel of in-vitro, cell-based, in-ovo and in-vivo bioassays for discovering metabolites with anti-ageing and/or angiogenesis modulating activity will frame the entire work-flow and will reveal the lead compounds. In addition, the catalytic potential of mesophotic symbionts and deriving enzymes candidates will be evaluated in fine chemicals and bioremediation industries. The project activities will be constantly assessed via effective management for their societal, economical and environmental impact in order to find the best compromise between industrial development and sustainable growth.
year | authors and title | journal | last update |
---|---|---|---|
2018 |
Eleni-Dimitra Papanagnou, Evangelos Terpos, Efstathios Kastritis, Issidora S. Papassideri, Ourania E. Tsitsilonis, Meletios A. Dimopoulos, Ioannis P. Trougakos Molecular responses to therapeutic proteasome inhibitors in multiple myeloma patients are donor-, cell type- and drug-dependent published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.24882 |
Oncotarget 9/25 | 2020-01-29 |
2017 |
Efstratios Nikolaivits, Maria Dimarogona, Nikolas Fokialakis, Evangelos Topakas Marine-Derived Biocatalysts: Importance, Accessing, and Application in Aromatic Pollutant Bioremediation published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2017.00265 |
Frontiers in Microbiology 8 | 2020-01-29 |
2019 |
Zoi Evangelakou, Maria Manola, Sentiljana Gumeni, Ioannis P. Trougakos Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach published pages: , ISSN: 1555-8932, DOI: 10.1186/s12263-019-0638-6 |
Genes & Nutrition 14/1 | 2020-01-29 |
2019 |
James Davis Reimer, Hiroki Kise, Maria E. A. Santos, Dhugal John Lindsay, Richard L. Pyle, Joshua M. Copus, Brian W. Bowen, Masanori Nonaka, Takuo Higashiji, Yehuda Benayahu Exploring the Biodiversity of Understudied Benthic Taxa at Mesophotic and Deeper Depths: Examples From the Order Zoantharia (Anthozoa: Hexacorallia) published pages: , ISSN: 2296-7745, DOI: 10.3389/fmars.2019.00305 |
Frontiers in Marine Science 6 | 2020-01-29 |
2018 |
Ronen Liberman, Tom Shlesinger, Yossi Loya, Yehuda Benayahu Octocoral Sexual Reproduction: Temporal Disparity Between Mesophotic and Shallow-Reef Populations published pages: , ISSN: 2296-7745, DOI: 10.3389/fmars.2018.00445 |
Frontiers in Marine Science 5 | 2020-01-29 |
2018 |
Efstratios Nikolaivits, Maria Dimarogona, Ioanna Karagiannaki, Angelina Chalima, Ayelet Fishman, Evangelos Topakas Versatile Fungal Polyphenol Oxidase with Chlorophenol Bioremediation Potential: Characterization and Protein Engineering published pages: , ISSN: 0099-2240, DOI: 10.1128/aem.01628-18 |
Applied and Environmental Microbiology 84/23 | 2020-01-29 |
2018 |
Dewi Embong Bulan, Alisa Wilantho, Patcharaporn Krainara, Voranop Viyakarn, Suchana Chavanich, Naraporn Somboonna Spatial and Seasonal Variability of Reef Bacterial Communities in the Upper Gulf of Thailand published pages: , ISSN: 2296-7745, DOI: 10.3389/fmars.2018.00441 |
Frontiers in Marine Science 5 | 2020-01-29 |
2018 |
Dewi Embong Bulan, Alisa Wilantho, Sissades Tongsima, Voranop Viyakarn, Suchana Chavanich, Naraporn Somboonna Microbial and Small Eukaryotes Associated With Reefs in the Upper Gulf of Thailand published pages: , ISSN: 2296-7745, DOI: 10.3389/fmars.2018.00436 |
Frontiers in Marine Science 5 | 2020-01-29 |
2017 |
Yehuda Benayahu, Catherine S. McFadden, Erez Shoham, Leen P. van Ofwegen Search for mesophotic octocorals (Cnidaria, Anthozoa) and their phylogeny. II. A new zooxanthellate species from Eilat, northern Red Sea published pages: 1-12, ISSN: 1313-2989, DOI: 10.3897/zookeys.676.12751 |
ZooKeys 676 | 2020-01-29 |
2019 |
Erez Shoham, Thomas Prohaska, Zahava Barkay, Andreas Zitek, Yehuda Benayahu Soft corals form aragonite-precipitated columnar spiculite in mesophotic reefs published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-37696-z |
Scientific Reports 9/1 | 2020-01-29 |
2017 |
Sentiljana Gumeni, Zoi Evangelakou, Vassilis Gorgoulis, Ioannis Trougakos Proteome Stability as a Key Factor of Genome Integrity published pages: 2036, ISSN: 1422-0067, DOI: 10.3390/ijms18102036 |
International Journal of Molecular Sciences 18/10 | 2020-01-29 |
2017 |
Tsakiri, E.N.; Terpos, E.; Papanagnou, E.D.; Kastritis, E.; Brieudes, V.; Halabalaki, M.; Bagratuni, T.; Florea, B.I.; Overkleeft, H.S.; Scorrano, L.; Skaltsounis, A.L.; Dimopoulos, M.A.; Trougakos, I.P. Milder degenerative effects of Carfilzomib &ITvs&IT. Bortezomib in the Drosophila model: a link to clinical adverse events published pages: nature Publishin, ISSN: 2045-2322, DOI: |
SCIENTIFIC REPORTS, 7 , 17802 1 | 2020-01-29 |
2017 |
Yehuda Benayahu, Catherine S. McFadden, Erez Shoham Search for mesophotic octocorals (Cnidaria, Anthozoa) and their phylogeny: I. A new sclerite-free genus from Eilat, northern Red Sea published pages: 1-11, ISSN: 1313-2989, DOI: 10.3897/zookeys.680.12727 |
ZooKeys 680 | 2020-01-29 |
2019 |
Géraldine Le Goff, Philippe Lopes, Guillaume Arcile, Pinelopi Vlachou, Elsa Van Elslande, Pascal Retailleau, Jean-François Gallard, Michal Weis, Yehuda Benayahu, Nikolas Fokialakis, Jamal Ouazzani Impact of the Cultivation Technique on the Production of Secondary Metabolites by Chrysosporium lobatum TM-237-S5, Isolated from the Sponge Acanthella cavernosa published pages: 678, ISSN: 1660-3397, DOI: 10.3390/md17120678 |
Marine Drugs 17/12 | 2020-01-29 |
2019 |
Pierre-Eric Campos, Emmanuel Pichon, Céline Moriou, Patricia Clerc, Rozenn Trépos, Michel Frederich, Nicole De Voogd, Claire Hellio, Anne Gauvin-Bialecki, Ali Al-Mourabit New Antimalarial and Antimicrobial Tryptamine Derivatives from the Marine Sponge Fascaplysinopsis reticulata published pages: 167, ISSN: 1660-3397, DOI: 10.3390/md17030167 |
Marine Drugs 17/3 | 2020-01-29 |
2018 |
Eleni N. Tsakiri, Sentiljana Gumeni, Kalliopi K. Iliaki, Dimitra Benaki, Konstantinos Vougas, Gerasimos P. Sykiotis, Vassilis G. Gorgoulis, Emmanuel Mikros, Luca Scorrano, Ioannis P. Trougakos Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation published pages: e12845, ISSN: 1474-9718, DOI: 10.1111/acel.12845 |
Aging Cell | 2020-01-29 |
2018 |
Aimilia Sklirou, Eleni-Dimitra Papanagnou, Nikolas Fokialakis, Ioannis P. Trougakos Cancer chemoprevention via activation of proteostatic modules published pages: 110-121, ISSN: 0304-3835, DOI: 10.1016/j.canlet.2017.10.034 |
Cancer Letters 413 | 2020-01-29 |
2019 |
Efstratios Nikolaivits, Andreas Agrafiotis, Aikaterini Termentzi, Kyriaki Machera, Géraldine Le Goff, Pedro Ãlvarez, Suchana Chavanich, Yehuda Benayahu, Jamal Ouazzani, Nikolas Fokialakis, Evangelos Topakas Unraveling the Detoxification Mechanism of 2,4-Dichlorophenol by Marine-Derived Mesophotic Symbiotic Fungi Isolated from Marine Invertebrates published pages: 564, ISSN: 1660-3397, DOI: 10.3390/md17100564 |
Marine Drugs 17/10 | 2020-01-29 |
2018 |
Amr El-Demerdash, Céline Moriou, Jordan Toullec, Marc Besson, Stéphanie Soulet, Nelly Schmitt, Sylvain Petek, David Lecchini, Cécile Debitus, Ali Al-Mourabit Bioactive Bromotyrosine-Derived Alkaloids from the Polynesian Sponge Suberea ianthelliformis published pages: 146, ISSN: 1660-3397, DOI: 10.3390/md16050146 |
Marine Drugs 16/5 | 2019-06-04 |
2018 |
ROB W.M. VAN SOEST, NICOLE J. DE VOOGD Calcareous sponges of the Western Indian Ocean and Red Sea published pages: 1, ISSN: 1175-5326, DOI: 10.11646/zootaxa.4426.1.1 |
Zootaxa 4426/1 | 2019-06-04 |
2017 |
Charlotte Leman-Loubière, Géraldine Le Goff, Pascal Retailleau, Cécile Debitus, Jamal Ouazzani Sporothriolide-Related Compounds from the Fungus Hypoxylon monticulosum CLL-205 Isolated from a Sphaerocladina Sponge from the Tahiti Coast published pages: 2850-2854, ISSN: 0163-3864, DOI: 10.1021/acs.jnatprod.7b00714 |
Journal of Natural Products 80/10 | 2019-06-04 |
2017 |
Charlotte Leman-Loubière, Géraldine Le Goff, Cécile Debitus, Jamal Ouazzani Sporochartines A–E, A New Family of Natural Products from the Marine Fungus Hypoxylon monticulosum Isolated from a Sphaerocladina Sponge published pages: , ISSN: 2296-7745, DOI: 10.3389/fmars.2017.00399 |
Frontiers in Marine Science 4 | 2019-06-04 |
2016 |
Sentiljana Gumeni, Ioannis P. Trougakos Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease published pages: 1-24, ISSN: 1942-0900, DOI: 10.1155/2016/4587691 |
Oxidative Medicine and Cellular Longevity 2016 | 2019-06-04 |
2018 |
Pinelopi Vlachou, Géraldine Le Goff, Carolina Alonso, Pedro Ãlvarez, Jean-François Gallard, Nikolas Fokialakis, Jamal Ouazzani Innovative Approach to Sustainable Marine Invertebrate Chemistry and a Scale-Up Technology for Open Marine Ecosystems published pages: 152, ISSN: 1660-3397, DOI: 10.3390/md16050152 |
Marine Drugs 16/5 | 2019-06-04 |
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The information about "TASCMAR" are provided by the European Opendata Portal: CORDIS opendata.
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