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METENZ

To develop a novel class of metalloenzymes for application in novel asymmetric C-H activation chemistry.

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

METENZ project word cloud

Explore the words cloud of the METENZ project. It provides you a very rough idea of what is the project "METENZ" about.

inert asymmetric believe environment inaccessible chemical metal bonds transition reaction protein molecules community enantioselectivity previously function precise metalloenzymes scientist catalysed class incorporating synthetic regioselectivity synthesis reactions assemble organic genetically activation catalyst rhodium chemistry outcomes rates engineered

Project "METENZ" data sheet

The following table provides information about the project.

Coordinator	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	https://rovisresearch.wordpress.com/
Total cost	251˙857 €
EC max contribution	251˙857 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-GF
Starting year	2015
Duration (year-month-day)	from 2015-04-01 to 2018-03-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE Organization address address: TRINITY LANE THE OLD SCHOOLS city: CAMBRIDGE postcode: CB2 1TN website: www.cam.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CAMBRIDGE)	coordinator	251˙857.00
2	BOARD OF GOVERNORS OF THE COLORADO STATE UNIVERSITY SYSTEM BOARD OF GOVERNORS OF THE COLORADO STATE UNIVERSITY SYSTEM Organization address address: COLORADO STATE UNIVERSITY city: FORT COLLINS postcode: 80523 2001 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (FORT COLLINS)	partner	0.00
3	TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK Organization address address: AMSTERDAM AVENUE 1210 ROOM city: NEW YORK postcode: 10027 7003 website: www.columbia.edu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (NEW YORK)	partner	0.00

Map

Project objective

Chemical synthesis through the activation of inert C-H bonds allows scientist to efficiently assemble complex organic molecules which have specific function. We aim to develop a novel class of metalloenzymes, where a transition metal catalyst is embedded into a genetically engineered protein, for rhodium catalysed asymmetric C-H activation reactions. We believe that the approach of incorporating a transition metal into a protein will allow for precise control of the chemical environment around the transition metal, allowing us to control many key outcomes of the chemical reaction such as enantioselectivity, regioselectivity and reaction rates. This technology will allow for the development of C-H activation reactions that have previously been inaccessible to the synthetic chemistry community.

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The information about "METENZ" are provided by the European Opendata Portal: CORDIS opendata.