Explore the words cloud of the MotMotLearn project. It provides you a very rough idea of what is the project "MotMotLearn" about.
The following table provides information about the project.
Coordinator |
THE UNIVERSITY OF BIRMINGHAM
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://josephgalea.weebly.com/erc-project-motmotlearn.html |
Total cost | 1˙497˙885 € |
EC max contribution | 1˙497˙885 € (100%) |
Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
Code Call | ERC-2014-STG |
Funding Scheme | ERC-STG |
Starting year | 2015 |
Duration (year-month-day) | from 2015-10-01 to 2020-09-30 |
Take a look of project's partnership.
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1 | THE UNIVERSITY OF BIRMINGHAM | UK (BIRMINGHAM) | coordinator | 1˙497˙885.00 |
Motor learning (the ability of the brain to learn and update how an action is executed) is a fundamental process which influences many aspects of our lives such as learning to walk during childhood; the day-to-day behavioural adjustments required as an adult or in healthy ageing; and the rehabilitation process following an illness or injury. Despite the impact to society, it has proved extremely difficult to develop interventions that significantly enhance human motor learning. Therefore, devising protocols which optimise motor learning is a state-of-the-art research question that promises to deliver scientific, clinical and societal impact.Seeking reward and avoiding punishment are powerful factors in motivating humans to alter behaviour during cognition-based learning (selecting which action to perform), with sensitivity to reward and punishment being biased by the availability of dopamine in the brain. Intriguingly, reward and punishment are also known to affect generic motor learning (deciding how an action is executed) tasks which involve multiple underlying mechanisms. However to establish their potential for optimizing motor learning, we must understand how explicit reward- and punishment-based motivational feedback impact motor learning systems with unique computational and anatomical features (use-dependent/model-free/model-based). Using an unprecedented combination of behavioural analysis, computational modelling, genetics and pharmacology, MotMotLearn will provide the first systems-based account of how reward, punishment and dopamine influence motor learning. This novel approach will enable MotMotLearn to develop theoretically-grounded protocols that utilise reward/punishment in conjunction with dopaminergic medication to optimise motor learning in healthy individuals and stroke patients suffering motor impairments. MotMotLearn will have a profound scientific impact in motor learning with applications to development, ageing, rehabilitation and sports.
year | authors and title | journal | last update |
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2020 |
Olivier Codol, Peter J. Holland, Sanjay G. Manohar, Joseph M. Galea Reward-based improvements in motor control are driven by multiple error-reducing mechanisms published pages: JN-RM-2646-19, ISSN: 0270-6474, DOI: 10.1523/jneurosci.2646-19.2020 |
The Journal of Neuroscience | 2020-04-15 |
2020 |
Xiuli Chen, Sarah Voets, Ned Jenkinson, Joseph M. Galea Dopamine-Dependent Loss Aversion during Effort-Based Decision-Making published pages: 661-670, ISSN: 0270-6474, DOI: 10.1523/jneurosci.1760-19.2019 |
The Journal of Neuroscience 40/3 | 2020-04-15 |
2018 |
Anna Sadnicka, Joseph M. Galea, Jui-Cheng Chen, Thomas T. Warner, Kailash P. Bhatia, John C. Rothwell, Mark J. Edwards Delineating cerebellar mechanisms in DYT11 myoclonus-dystonia published pages: 1956-1961, ISSN: 0885-3185, DOI: 10.1002/mds.27517 |
Movement Disorders 33/12 | 2020-04-15 |
2019 |
Peter Holland, Olivier Codol, Elizabeth Oxley, Madison Taylor, Elizabeth Hamshere, Shadiq Joseph, Laura Huffer, Joseph M. Galea Domain-Specific Working Memory, But Not Dopamine-Related Genetic Variability, Shapes Reward-Based Motor Learning published pages: 9383-9396, ISSN: 0270-6474, DOI: 10.1523/jneurosci.0583-19.2019 |
The Journal of Neuroscience 39/47 | 2020-04-15 |
2017 |
Roya Jalali, R. Chris Miall, Joseph M. Galea No consistent effect of cerebellar transcranial direct current stimulation on visuomotor adaptation published pages: 655-665, ISSN: 0022-3077, DOI: 10.1152/jn.00896.2016 |
Journal of Neurophysiology 118/2 | 2019-06-05 |
2017 |
Daniele Caligiore, Giovanni Pezzulo, Gianluca Baldassarre, Andreea C. Bostan, Peter L. Strick, Kenji Doya, Rick C. Helmich, Michiel Dirkx, James Houk, Henrik Jörntell, Angel Lago-Rodriguez, Joseph M. Galea, R. Chris Miall, Traian Popa, Asha Kishore, Paul F. M. J. Verschure, Riccardo Zucca, Ivan Herreros Consensus Paper: Towards a Systems-Level View of Cerebellar Function: the Interplay Between Cerebellum, Basal Ganglia, and Cortex published pages: 203-229, ISSN: 1473-4222, DOI: 10.1007/s12311-016-0763-3 |
The Cerebellum 16/1 | 2019-06-05 |
2018 |
Anna Sadnicka, Anna Stevenson, Kailash P. Bhatia, John C. Rothwell, Mark J. Edwards, Joseph M. Galea High motor variability in DYT1 dystonia is associated with impaired visuomotor adaptation published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-21545-0 |
Scientific Reports 8/1 | 2019-06-05 |
2017 |
Xiuli Chen, Kieran Mohr, Joseph M. Galea Predicting explorative motor learning using decision-making and motor noise published pages: e1005503, ISSN: 1553-7358, DOI: 10.1371/journal.pcbi.1005503 |
PLOS Computational Biology 13/4 | 2019-06-05 |
2016 |
Antonios I. Christou, R. Chris Miall, Fiona McNab, Joseph M. Galea Individual differences in explicit and implicit visuomotor learning and working memory capacity published pages: , ISSN: 2045-2322, DOI: 10.1038/srep36633 |
Scientific Reports 6/1 | 2019-06-05 |
2017 |
Graziella Quattrocchi, Richard Greenwood, John C Rothwell, Joseph M Galea, Sven Bestmann Reward and punishment enhance motor adaptation in stroke published pages: 730-736, ISSN: 0022-3050, DOI: 10.1136/jnnp-2016-314728 |
Journal of Neurology, Neurosurgery & Psychiatry 88/9 | 2019-06-05 |
2018 |
Roya Jalali, Alimul Chowdhury, Martin Wilson, R. Chris Miall, Joseph M. Galea Neural changes associated with cerebellar tDCS studied using MR spectroscopy published pages: 997-1006, ISSN: 0014-4819, DOI: 10.1007/s00221-018-5170-1 |
Experimental Brain Research 236/4 | 2019-06-05 |
2018 |
Peter James Holland, Olivier Codol, Joseph M. Galea The contribution of explicit processes to reinforcement-based motor learning published pages: , ISSN: 0022-3077, DOI: 10.1152/jn.00901.2017 |
Journal of Neurophysiology | 2019-06-05 |
2016 |
Carmel Mevorach, Mayra Muller Spaniol, Matthew Soden, Joseph M. Galea Age-dependent distractor suppression across the vision and motor domain published pages: 27, ISSN: 1534-7362, DOI: 10.1167/16.11.27 |
Journal of Vision 16/11 | 2019-06-05 |
2016 |
R. Chris Miall, Joseph Galea Cerebellar damage limits reinforcement learning published pages: 4-7, ISSN: 0006-8950, DOI: 10.1093/brain/awv343 |
Brain 139/1 | 2019-06-05 |
2018 |
Xiuli Chen, Peter Holland, Joseph M Galea The effects of reward and punishment on motor skill learning published pages: 83-88, ISSN: 2352-1546, DOI: 10.1016/j.cobeha.2017.11.011 |
Current Opinion in Behavioral Sciences 20 | 2019-06-05 |
2018 |
Xiuli Chen, Robb B. Rutledge, Harriet R. Brown, Raymond J. Dolan, Sven Bestmann, Joseph M. Galea Age-dependent Pavlovian biases influence motor decision-making published pages: e1006304, ISSN: 1553-7358, DOI: 10.1371/journal.pcbi.1006304 |
PLOS Computational Biology 14/7 | 2019-05-07 |
2018 |
Olivier Codol, Peter J. Holland, Joseph M. Galea The relationship between reinforcement and explicit control during visuomotor adaptation published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-018-27378-1 |
Scientific Reports 8/1 | 2019-05-07 |
2018 |
Graziella Quattrocchi, Jessica Monaco, Andy Ho, Friederike Irmen, Wolfgang Strube, Diane Ruge, Sven Bestmann, Joseph M. Galea Pharmacological Dopamine Manipulation Does Not Alter Reward-Based Improvements in Memory Retention during a Visuomotor Adaptation Task published pages: ENEURO.0453-17.2, ISSN: 2373-2822, DOI: 10.1523/ENEURO.0453-17.2018 |
eneuro 5/3 | 2019-05-07 |
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The information about "MOTMOTLEARN" are provided by the European Opendata Portal: CORDIS opendata.