MAGNEURON project deliverables
The page lists 19 deliverables related to the research project "MAGNEURON".
List of Deliverables
| title and desprition | type | last update |
|---|---|---|
Consolidated Data Management PlanUpdated Data Management Plan will be consolidated at the end of the project. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Open Research Data Pilot | 2020-04-16 |
Identification and assessment of neuronal differentiation and axonal outgrowthCells will be identified using immunocytochemistry with the following specific antibodies: to assess neuronal differentiation - beta-III-tubulin, Map2ab; and midbrain dopaminergic neurons – tyrosine hydroxylase, vesicular monoamine transporter (VMAT), dopamine transporter, Aromatic L-amino acid decarboxylase (AADC), and Nurr1. Axonal outgrowth will be measured and quantified from digital images of beta-III-tubulin labeled cells. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-16 |
Dissemination Strategy report 2This document will report on the dissemination and communication activities carried out in the period from M13 to M30 by the MAGNEURON consortium, with regard to the described communication activities in DoA. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-16 |
Systematic analysis of the cell differentiation response to signalling perturbationsIn vitro tests to define the differentiation responses of dopamine neurons in culture and in 3D systems including brain slices. Different regimes in 2D and 3D will be tested and optimized to promote neuronal regeneration. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-16 |
Protocols for activation of neuronal differentiation through key receptor tagsKey receptors will be tested which can control neuronal cell differentiation e.g. TREK channels, Fz receptors. Magnetic particles will be coated with receptor tags and attached to receptors on the cell membrane. In response to oscillating fields, the cells will be induced to differentiate in vitro. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-16 |
Final workshopThe final workshop will allow communicating the project results to a large scientific and industrial community. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-16 |
Device for parallelized stimulation and high-throughput assayWe will develop a device for parallelized magnetic stimulation of multiple cells, based on microfabrication of micromagnets combined to micropatterning, enabling high-throughput assays. We will characterize the magnetic and optical performances of the devices. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Demonstrators, pilots, prototypes | 2020-04-16 |
Final Dissemination Strategy reportThis document will report on the dissemination and communication activities carried out in the period from M31 to M48 by the MAGNEURON consortium, with regard to the described communication activities in DoA. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-16 |
Characterization of magnetic manipulation in cellsWe will characterize the forces required to manipulate cells inside cells, the kinetics with which they can be displaced through the cells. These results will be analyzed as a function of the colloidal and biofunctional properties of the nanoparticles. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Recombinant ferritin-based MNPsWe will deliver a protocol describing (i) expression and purification of recombinant ferritin particles, (ii) loading with magnetic iron oxide core and (iii) biochemical functionalization of magneto ferritin particles. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Intermediate workshopThe MAGNEURON consortium will organise an intermediate workshop during the project to communicate the intermediate results and generate synergies with the scientific community. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Dispersions of silica core shell MNPsD2.2 is dedicated to the coating of maghemite nanoparticles synthesized in task 1 by a silica shell. If this synthesis pathway is well established for smaller particles, the protocol must be adapted to the big (12-14, up to 20 nm) ones that will be used in this project. Amines functional groups will be included on the surface of core-shell nanoparticles so as to be used by the other members of the consortium. Near infrared Fluorescent probes (Cyanine 5,5 for instance) will be included in the silica shell during synthesis for optical detection of nanoparticles in cells. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Activation of intracellular membrane-anchored small G-proteins by cytosolic MNPsMNPs functionalized with activated Ras/Rac (or their GEF activators) will be delivered into the cytoplasm of cells transfected with biosensors (Raichu-Ras, Raichu-Rac). Using the spaceMode approach, we will test for asymmetrical activation of downstream cytoskeletal targets using confocal fluorescence microscopy. Nonfunctionalized MNP will serve as negative control. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Dispersions of stabilized MNPsThis deliverable is synthesized big magnetic nanoparticles (from 12-14 and up to 20 nm in diameter) using an alternative Massart’s synthesis pathway. The necessary size sorting will be achieved in order to gain in monodispersity. For the full project, 200 mL at 1M of iron content is expected for each diameter selected. This will need several synthesis batches, as long as size sorting decreases strongly the quantity of expected nanoparticles. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Dissemination Strategy report 1This document will report on the dissemination and communication activities carried out in the period from M1 to M12 by the MAGNEURON consortium, with regard to the described communication activities in DoA. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
Data Management PlanData Management Plan will be written on the base of the EC tool. All the non-sensitivity data will be stored in an open repository. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
MAGNEURON websiteThe MAGNEURON web site will provide public information about the project, its objectives, the partners, the advancements, and the organised workshop and provide an entry contact point with any industry or organism interested in the project results. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Websites, patent fillings, videos etc. | 2020-04-07 |
Dissemination Strategy planThis document will report on the dissemination and communication strategies implemented by the MAGNEURON consortium, with regard to the described communication activities in DoA. A consistent graphical chart will be proposed for communication and dissemination supports. It shall be consistent with the IPR strategy plan. Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |
MAGNEURON brochureThe MAGNEURON brochure will be a dissemination way with public information on the project activities, objectives and progress that will be distributed whenever possible. Quantity of printed brochures will be defined by the Dissemination Plan. The logo, the design and the graphical chart will be consistent with the Website and other communication supports (internal and external). Programme: H2020-EU.1.2.1. - Topic(s): FETOPEN-RIA-2014-2015 |
Documents, reports | 2020-04-07 |