SmartNanoTox project deliverables
The page lists 12 deliverables related to the research project "SmartNanoTox".
List of Deliverables
| title and desprition | type | last update |
|---|---|---|
Position paper on predictive in vitro modelshe literature will be surveyed for providing a basis for the best selection of cultured cells and effects by different NMs. A position paper will be written on the poissibilities and limiations of in vitro toxicity assessment techniques. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
Establishment of a stakeholder advisory boardEstablishment of a stakeholder advisory board: invitation of top experts in toxicology, nanomaterials, software engineering, environmental safety to participate in the project advisory board. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Websites, patent fillings, videos etc. | 2020-02-25 |
List of NMsList of NM to be used within the project and characterization will be compiled based on assessment of the available and most suitable materials. NM Materials (the NM series) deposited in the EC, Joint Research Centre (selected by the OECD Nanomaterials Working Party) and a series of 64 materials (the NRCWE series) available at the NRCWE (Partner 4) will be assessed for suitability for in vivo inhalation and in vitro tracking studies. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
Research data management planPlan for dissemination, storage and maintenance of obtained data during and after project term. List of data to be stored, formats and technologies. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Open Research Data Pilot | 2020-02-25 |
Labelled NPs for tracking within cells and tissuesNanoparticles fluorescently or isotopically labeled to enable tracking within the cells and evaluation of the interactions with the NP coats such as protein corona or lipid wraps. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
List of nanomaterials and respective doses to be tested as TP benchmarkList of nanomaterials and respective doses to be tested as TP benchmark: results of literature survey, data mining, initial tests regarding the materials with well established toxic action. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
Development of the data portalPortal for data storage, exchange, annotation and evaluation between the partners as a part of the project website with restricted access. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Websites, patent fillings, videos etc. | 2020-02-25 |
PMFs and binding free energies for interaction of NM with building blocks of biomoleculesResults of atomistic simulations: potnetials of mean force and binding free energies for interaction of selected NMs (up to 60) with building blocks of biomolecules - lipid fragments, headgroups, aminoacids. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
Isolation and archiving of biological samples for subsequent analysisIsolation and archiving of biological in vivo samples (exposed mice / rats) for subsequent analysis (lung lavage analysis, hematology and histology, transcriptomics). Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
In vivo samples for transcriptomics studies (instillation)In vivo samples for transcriptomics studies (instillation - mice): Lung tissues collected at different time points following animal exposure to assess short and long term effects of NMs. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
Identify and score the pathological outcome of the in vivo exposuresList and assessment of severity of pathological outcomes of the in vivo exposures: hystopathology, transcriptomics (and targeted proteomics) analyses of in vivo and in vitro exposures of mice and rats to the NMs. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |
Report of end-localization of NPs within relevant cellsReport of end-localization of NPs within relevant cells: results of cell lines (macrophages and lung epithelium cells) and lung tissue exposure to the functionalized and labeled NPs regarding trafficking, partitioning and accumulation of the NPs. Programme: H2020-EU.2.1.2.2. - Topic(s): NMP-29-2015 |
Documents, reports | 2020-02-25 |