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CVENT SIGNED

Risk assessment of plaque rupture and future cardiovascular events (CVENT) by multi-spectral photoacoustic imaging

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

CVENT project word cloud

Explore the words cloud of the CVENT project. It provides you a very rough idea of what is the project "CVENT" about.

reducing alone death simultaneously middle overtreatment intervention imaging unmet patients cardiovascular medical people ischemic severity haemorrhage combination stable clinically groups age introducing clinicians surgical mortality vulnerable worldwide clinical urgent decision disease pai attacks prone markers photoacoustic consequently rupture industrial contrast allocation vulnerability multimodal distinguish experts resolution ultrasound avoiding compact events plaques carotid cerebrovascular arteries unites healthcare plaque multiwavelength vascular harmless arena monitoring cvd cm screening measured optical risk funds diagnosis cvent pools portable feeding revolutionize lipid disability severe expertise stratifying initiates stenosis functional brain breakthrough

Project "CVENT" data sheet

The following table provides information about the project.

Coordinator	ESAOTE EUROPE B.V. Organization address address: PHILIPSWEG 1 city: MAASTRICHT postcode: 6227AJ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Project website	http://www.cvent-2020.eu
Total cost	4˙697˙377 €
EC max contribution	4˙260˙790 € (91%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2016-1
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-11-01 to 2020-04-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ESAOTE EUROPE B.V. ESAOTE EUROPE B.V. Organization address address: PHILIPSWEG 1 city: MAASTRICHT postcode: 6227AJ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (MAASTRICHT)	coordinator	840˙000.00
2	LUMIBIRD LUMIBIRD Organization address address: 2 RUE PAUL SABATIER city: LANNION postcode: 22300 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (LANNION)	participant	865˙000.00
3	TECHNISCHE UNIVERSITEIT EINDHOVEN TECHNISCHE UNIVERSITEIT EINDHOVEN Organization address address: GROENE LOPER 3 city: EINDHOVEN postcode: 5612 AE website: www.tue.nl/en contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (EINDHOVEN)	participant	555˙428.00
4	UNIVERSITEIT TWENTE UNIVERSITEIT TWENTE Organization address address: DRIENERLOLAAN 5 city: ENSCHEDE postcode: 7522 NB website: www.utwente.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (ENSCHEDE)	participant	413˙038.00
5	RUHR-UNIVERSITAET BOCHUM RUHR-UNIVERSITAET BOCHUM Organization address address: UNIVERSITAETSSTRASSE 150 city: BOCHUM postcode: 44801 website: www.rub.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BOCHUM)	participant	399˙000.00
6	UNIVERSITE DE PARIS UNIVERSITE DE PARIS Organization address address: 85 BD SAINT GERMAIN city: PARIS postcode: 75006 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	399˙000.00
7	BRIGHTLOOP SAS BRIGHTLOOP SAS Organization address address: RUE DE BERRI 8 city: PARIS postcode: 75008 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	299˙916.00
8	SILIOS TECHNOLOGIES SA SILIOS TECHNOLOGIES SA Organization address address: Zi Peynier Rousset, rue Gaston Imbert Prolongée city: Peynier postcode: 13790 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (Peynier)	participant	265˙656.00
9	TP21 GMBH TP21 GMBH Organization address address: LUISENSTRASSE 14 city: BERLIN postcode: 10117 website: www.tp21.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	223˙750.00
10	UNIVERSITAET BERN UNIVERSITAET BERN Organization address address: HOCHSCHULSTRASSE 6 city: BERN postcode: 3012 website: http://www.unibe.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (BERN)	participant	0.00
11	UNIVERSITE PARIS DESCARTES UNIVERSITE PARIS DESCARTES Organization address address: RUE DE L ECOLE DE MEDECINE 12 city: PARIS CEDEX 06 postcode: 75270 website: www.univ-paris5.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS CEDEX 06)	participant	0.00

Map

Project objective

Cardiovascular disease (CVD), more specifically, vulnerable plaque rupture, remains the major cause of death for people at middle age. The CVENT consortium will revolutionize screening, diagnosis and monitoring of CVD by means of a compact photoacoustic imaging (PAI) system for vulnerable plaque imaging. In the carotid arteries feeding the brain, vulnerable plaque rupture initiates cerebrovascular ischemic attacks. The state-of-the-art decision-making approach for a high-risk surgical intervention to avoid plaque rupture is based on stenosis severity alone, measured with ultrasound (US) imaging. However, this does not distinguish between vulnerable (rupture-prone) and stable (harmless) plaques, leading to severe overtreatment. Consequently, there is a worldwide unmet and urgent clinical need for functional information to enable in-depth diagnosis of carotid plaque vulnerability, avoiding cardiovascular events (CVENT) and reducing overtreatment risk. The objective of the CVENT consortium is the development of a portable multimodal and multiwavelength PAI system with a 3 cm imaging depth, for diagnosis and monitoring of carotid plaque vulnerability. The combination of high optical contrast of PAI and the high resolution of US will be used to identify plaque vulnerability markers, typically lipid pools and intra-plaque haemorrhage. Improved diagnosis of carotid plaque vulnerability will lead to a significant reduction in CVD-related disability and mortality. Simultaneously, by stratifying patients into high and low risk groups, overtreatment is reduced, leading to better allocation of healthcare funds. The CVENT consortium unites leading research groups, clinicians, industrial partners, and their expertise on R&D and a focus on exploitation, creating a breakthrough in carotid plaque vulnerability diagnosis. CVENT will bring together leading experts in the field of CVD, functional US imaging and PAI, introducing clinically applied PAI into the vascular medical arena.

Deliverables

List of deliverables.
Public website and communication kit	Websites, patent fillings, videos etc.	2020-02-19 17:21:36

Take a look to the deliverables list in detail: detailed list of CVENT deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2017	Pim J. van den Berg, Khalid Daoudi, Hein J. Bernelot Moens, Wiendelt Steenbergen Feasibility of photoacoustic/ultrasound imaging of synovitis in finger joints using a point-of-care system published pages: 8-14, ISSN: 2213-5979, DOI: 10.1016/j.pacs.2017.08.002	Photoacoustics 8	2020-02-19
2018	M. Umit Arabul, H. Maarten Heres, Marcel C. M. Rutten, Marc R. H. M. van Sambeek, Frans N. van de Vosse, Richard G. P. Lopata Investigation on the Effect of Spatial Compounding on Photoacoustic Images of Carotid Plaques in the In Vivo Available Rotational Range published pages: 440-447, ISSN: 0885-3010, DOI: 10.1109/TUFFC.2018.2792903	IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 65/3	2020-02-19
2017	Mithun Kuniyil Ajith Singh, Michael Jaeger, Martin Frenz, Wiendelt Steenbergen Photoacoustic reflection artifact reduction using photoacoustic-guided focused ultrasound: comparison between plane-wave and element-by-element synthetic backpropagation approach published pages: 2245, ISSN: 2156-7085, DOI: 10.1364/BOE.8.002245	Biomedical Optics Express 8/4	2020-02-19

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The information about "CVENT" are provided by the European Opendata Portal: CORDIS opendata.