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IMMUNFUNC

Female immune function in compensation for polyandry

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

IMMUNFUNC project word cloud

Explore the words cloud of the IMMUNFUNC project. It provides you a very rough idea of what is the project "IMMUNFUNC" about.

variation population fellowship species skills agricultural positively whereas horizons males excellent bridge ultimately genetically person pest function compensate correlates inflict females interactions perfect hypothesis tackle evolutionary multiple put mentoring genetic wedell isolines fitness line inter experimental time additional efficiency fly polyandry nature immune trait teaching regulate back complement profoundly once drosophila position date differ career pests organisms techniques fruit model dynamics 25 biology me gap ideas conceptual dimension writing acquire explicitly predisposition situation organism sexual mate influencing life question questions expand prof mating examine female pseudoobscura feed scientist

Project "IMMUNFUNC" data sheet

The following table provides information about the project.

Coordinator	THE UNIVERSITY OF EXETER Organization address address: THE QUEEN'S DRIVE NORTHCOTE HOUSE city: EXETER postcode: EX4 4QJ website: www.ex.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	United Kingdom [UK]
Project website	http://biosciences.exeter.ac.uk/wedellpolyandry/
Total cost	183˙454 €
EC max contribution	183˙454 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2016
Funding Scheme	MSCA-IF-EF-ST
Starting year	2017
Duration (year-month-day)	from 2017-09-01 to 2019-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE UNIVERSITY OF EXETER THE UNIVERSITY OF EXETER Organization address address: THE QUEEN'S DRIVE NORTHCOTE HOUSE city: EXETER postcode: EX4 4QJ website: www.ex.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EXETER)	coordinator	183˙454.00

Map

Project objective

The level of polyandry is a key trait influencing population dynamics and inter-sexual interactions of organisms. In nature, females of some species mate only once in their life time, whereas others mate with multiple males. My research aims at understanding why there is so many variation in the level of polyandry. I will tackle this question by focusing on female immune function. Mating can up-/down-regulate immune function, which is likely to inflict fitness costs on females if they mate with multiple males. If the level of polyandry positively correlates with the efficiency of female immune function, immune function may compensate for the costs of multiple mating. To test this hypothesis, I will use 25 isolines of the fruit fly Drosophila pseudoobscura that genetically differ profoundly in their predisposition to polyandry. This unique system will allow me to examine effects of both mating and genetic variation in polyandry on female immune function. This project will complement my current research that to date has focused on specific applied agricultural-pest systems. I have less experience working on explicitly evolutionary-focused questions, so this research programme will provide an additional dimension to my applied research. Prof Wedell is a leading scientist in the field of experimental evolutionary biology, and is the perfect person to expand my horizons into more conceptual and broader ideas. Under her mentoring, I will be able to develop my own research and skills in proposal writing and teaching. The new knowledge, skills and techniques that I will acquire through the project will feed back to my previous work on agricultural pests, which will result in me being able to bridge the gap between model organism and agricultural pest systems. The unique situation will enable me to develop a unique line of research in both evolutionary and applied biology. Ultimately, this Fellowship will put me in an excellent position for my further career.

Publications

List of publications.
year	authors and title	journal	last update
2019	Keiko Oku, Tom A.R. Price, Nina Wedell Does mating negatively affect female immune defences in insects? published pages: 117-136, ISSN: 1570-7563, DOI: 10.1163/15707563-20191082	Animal Biology 69	2020-01-27

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