Report

Teaser, summary, work performed and final results

Periodic Reporting for period 1 - TRAIN-EV (Training in Extracellular Vesicles: for benefit in Health and Disease)

Teaser

Exosomes and microvesicles/ectosomes, collectively termed extracellular vesicles (EV), have attracted much interest in recent years because of their potential functions, use as disease biomarkers and possible therapeutic exploitation. Due to their enormous relevance, this...

Summary

Exosomes and microvesicles/ectosomes, collectively termed extracellular vesicles (EV), have attracted much interest in recent years because of their potential functions, use as disease biomarkers and possible therapeutic exploitation. Due to their enormous relevance, this relatively new field of research is quickly expanding. While Europe is a leader in the field of EV research, there are still many gaps in knowledge that need to be addressed to ensure optimal exploitation of EVs from health and Europe’s economic benefit.
Addressing this, TRAIN-EV network coordinates fifteen highly inter-disciplinary and inter-sectoral projects to synergise the existing EV research activities and to develop a novel research training programme. TRAIN-EV’s main objective is to provide excellent and integrated multi-disciplinary and inter-sectoral training of a critical mass of ESRs of outstanding potential in the academic, clinical, and industry/business components of exploiting EV, while performing novel cutting-edge research to address these gaps and generate new knowledge.

Work performed

The work performed during the first reporting period within TRAIN-EV is in line with the Annex 1 to the Grant Agreement. Specifically, the TRAIN-EV training network has overall progressed as it was planned for this first reporting period, and is fully established and on the right track to conduct the training activities. TRAIN-EV ESRs are making substantial progress in their research, training and networking.
Overall, we are successful in progressing along the proposed project(s) timeline while keeping the pace with evolving knowledge and technology evolution in EV field and considering the emerging or persistent clinical needs.
The main results achieved so far are illustrated in the 3 published articles, 11 conference oral presentations and 6 posters.

Final results

TRAIN-EV projects contribute individually and collectively to the advancement of EVs’ isolation and characterisation techniques, which enables further understanding of molecular mechanisms for EVs. A final aim of these projects is to evaluate and optimise EVs’ use in diagnosis and treatment, with significant impact on society health status.

Website & more info

More info: http://train-ev.eu/.