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P4SB
P4SB – From Plastic waste to Plastic value using Pseudomonas putida Synthetic Biology
Total Cost €
0EC-Contrib. €
0Partnership
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0P4SB project word cloud
Explore the words cloud of the P4SB project. It provides you a very rough idea of what is the project "P4SB" about.
union
opening
engineered
bioplastic
industrial
sustainable
p4sb
streams
metabolizing
entire
putida
sme
biology
programmed
catalysts
biodegradable
time
depolymerization
completely
diverse
biobased
custom
pha
deeply
environmentally
downstream
anticipate
contemporary
made
lytic
derivatives
surgery
2020
modules
valorise
tailor
helping
reducing
material
terephthalate
chain
plastic
deep
ing
spanning
pseudomonas
metabolic
bio
enzymes
routes
gigantic
recovery
factory
conceptual
channel
polyurethane
recycling
bacterial
monomers
environmental
tools
industry
biomass
pet
polyethylene
undergo
carbon
market
synthetic
release
counterparts
generation
biotechnology
direct
bulk
secretion
establishing
bioconversion
oil
pu
source
polyhydroxyalkanoates
substrates
waste
cell
Project "P4SB" data sheet
The following table provides information about the project.
| Coordinator |
RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Project website | http://www.p4sb.eu |
| Total cost | 7˙056˙968 € |
| EC max contribution | 7˙056˙968 € (100%) |
| Programme |
1. H2020-EU.2.1.4. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies – Biotechnology) |
| Code Call | H2020-LEIT-BIO-2014-1 |
| Funding Scheme | RIA |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-04-01 to 2019-03-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | RHEINISCH-WESTFAELISCHE TECHNISCHE HOCHSCHULE AACHEN | DE (AACHEN) | coordinator | 1˙387˙062.00 |
| 2 | UNIVERSITAET LEIPZIG | DE (LEIPZIG) | participant | 981˙875.00 |
| 3 | BACMINE SL | ES (TRES CANTOS) | participant | 684˙625.00 |
| 4 | BIOPLASTECH LTD | IE (DUBLIN) | participant | 628˙781.00 |
| 5 | UNIVERSITY OF SURREY | UK (GUILDFORD) | participant | 628˙125.00 |
| 6 | AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS | ES (MADRID) | participant | 561˙875.00 |
| 7 | UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN | IE (DUBLIN) | participant | 540˙625.00 |
| 8 | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS | FR (PARIS) | participant | 524˙375.00 |
| 9 | HELMHOLTZ-ZENTRUM FUR UMWELTFORSCHUNG GMBH - UFZ | DE (LEIPZIG) | participant | 488˙625.00 |
| 10 | SOPREMA | FR (STRASBOURG) | participant | 317˙375.00 |
| 11 | PROTEUS | FR (LONGJUMEAU) | participant | 313˙625.00 |
Map
Project objective
P4SB is about the utilization of the conceptual and material tools of contemporary Synthetic Biology to bring about the sustainable and environmentally friendly bioconversion of oil-based plastic waste into fully biodegradable counterparts by means of deeply engineered, whole-cell bacterial catalysts. These tools will be used to design tailor-made enzymes for the bio-depolymerization of PET (polyethylene terephthalate) and PU (polyurethane), but also for the custom design of a Pseudomonas putida Cell Factory capable of metabolizing the resulting monomers. Pseudomonas putida will undergo deep metabolic surgery to channel these diverse substrates efficiently into the production of polyhydroxyalkanoates (PHA) and derivatives. In addition, synthetic downstream processing modules based on the programmed non-lytic secretion of PHA will facilitate the release and recovery of the bioplastic from the bacterial biomass.
These industry driven objectives will help to address the market need for novel routes to valorise the gigantic plastic waste streams in the European Union and beyond, with direct opportunities for SME partners of P4SB spanning the entire value chain from plastic waste via Synthetic Biology to biodegradable plastic. As a result we anticipate a completely biobased process reducing the environmental impact of plastic waste by establishing it as a novel bulk second generation carbon source for industrial biotechnology, while at the same time opening new opportunities for the European plastic recycling industry and helping to achieve the ambitious recycling targets set by the European Union for 2020.
Deliverables
| Final report on scientific dissemination and exploitation of results incl. risk assessment, ethical, societal and intellectual property aspects | Websites, patent fillings, videos etc. | 2019-11-22 17:49:10 |
| Interim Data Management Plan | Open Research Data Pilot | 2019-11-22 17:49:10 |
| P4SB-project website with corporate identity | Websites, patent fillings, videos etc. | 2019-11-22 17:49:10 |
| Initial Data Management Plan | Open Research Data Pilot | 2019-11-22 17:49:10 |
| Interim report on scientific dissemination and exploitation of results incl. risk assessment, ethical, societal, and intellectual property aspects | Websites, patent fillings, videos etc. | 2019-11-22 17:49:09 |
Take a look to the deliverables list in detail: detailed list of P4SB deliverables.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Natalia A. Tarazona, Rainhard Machatschek, Burkhard Schulz, M. Auxiliadora Prieto, Andreas Lendlein Molecular Insights into the Physical Adsorption of Amphiphilic Protein PhaF onto Copolyester Surfaces published pages: TBD, ISSN: 1525-7797, DOI: 10.1021/acs.biomac.9b00069 |
Biomacromolecules 16 April 2019 | 2019-11-22 |
| 2019 |
Ren Wei, Daniel Breite, Chen Song, Daniel Gräsing, Tina Ploss, Patrick Hille, Ruth Schwerdtfeger, Jörg Matysik, Agnes Schulze, Wolfgang Zimmermann Biocatalytic Degradation Efficiency of Postconsumer Polyethylene Terephthalate Packaging Determined by Their Polymer Microstructures published pages: 1900491, ISSN: 2198-3844, DOI: 10.1002/advs.201900491 |
Advanced Science | 2019-11-22 |
| 2019 |
Salvador, Abdulmutalib, Gonzalez, Kim, Smith, Faulon, Wei, Zimmermann, Jimenez Microbial Genes for a Circular and Sustainable Bio-PET Economy published pages: 373, ISSN: 2073-4425, DOI: 10.3390/genes10050373 |
Genes 10/5 | 2019-11-22 |
| 2017 |
Manuel S. Godoy, Beatrice Mongili, Debora Fino, M. Auxiliadora Prieto About how to capture and exploit the CO 2 surplus that nature, per se, is not capable of fixing published pages: 1216-1225, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12805 |
Microbial Biotechnology 10/5 | 2019-11-22 |
| 2018 |
Siavash Atashgahi, Irene Sánchez-Andrea, Hermann J. Heipieper, Jan R. van der Meer, Alfons J. M. Stams, Hauke Smidt Prospects for harnessing biocide resistance for bioremediation and detoxification published pages: 743-746, ISSN: 0036-8075, DOI: 10.1126/science.aar3778 |
Science 360/6390 | 2019-11-22 |
| 2017 |
Tiso, Till; Zauter, Rabea; Tulke, Hannah; Leuchtle, Bernd; Li, Wing Jin; Behrens, Beate; Wittgens, Andreas; Rosenau, Frank; Hayen, Heiko; Blank, Lars Mathias Designer rhamnolipids by reduction of congener diversity : production and characterization published pages: 14;16(1):225, ISSN: 1475-2859, DOI: 10.18154/RWTH-2018-00735 |
Microbial cell factories 16, 225 (2017). doi:10.1186/s12934-017-0838-y 9 | 2019-11-22 |
| 2018 |
Mary Ann Franden, Lahiru N. Jayakody, Wing-Jin Li, Neil J. Wagner, Nicholas S. Cleveland, William E. Michener, Bernhard Hauer, Lars M. Blank, Nick Wierckx, Janosch Klebensberger, Gregg T. Beckham Engineering Pseudomonas putida KT2440 for efficient ethylene glycol utilization published pages: 197-207, ISSN: 1096-7176, DOI: 10.1016/j.ymben.2018.06.003 |
Metabolic Engineering 48 | 2019-11-22 |
| 2018 |
Tanja Narancic, Steven Verstichel, Srinivasa Reddy Chaganti, Laura Morales-Gamez, Shane T. Kenny, Bruno De Wilde, Ramesh Babu Padamati, Kevin E. O’Connor Biodegradable Plastic Blends Create New Possibilities for End-of-Life Management of Plastics but They Are Not a Panacea for Plastic Pollution published pages: , ISSN: 0013-936X, DOI: 10.1021/acs.est.8b02963 |
Environmental Science & Technology | 2019-11-22 |
| 2018 |
Matheus Regis Belisário-Ferrari, Ren Wei, Tobias Schneider, Annett Honak, Wolfgang Zimmermann Fast turbidimetric assay for analyzing the enzymatic hydrolysis of polyethylene terephthalate model substrates published pages: 1800272, ISSN: 1860-6768, DOI: 10.1002/biot.201800272 |
Biotechnology Journal | 2019-11-22 |
| 2018 |
Köbbing, Sebastian; Wierckx, Nick; Blank, Lars Mathias Synthetic promoter stacking: When two plus two equals three published pages: , ISSN: , DOI: |
4th Meeting in Applied Synthetic Biology in Europe, Toulouse, France, 2018-10-24 - 2018-10-26 1 | 2019-11-22 |
| 2019 |
Audrey Magnin, Eric Pollet, Rémi Perrin, Christophe Ullmann, Cécile Persillon, Vincent Phalip, Luc Avérous Enzymatic recycling of thermoplastic polyurethanes: Synergistic effect of an esterase and an amidase and recovery of building blocks published pages: 141-150, ISSN: 0956-053X, DOI: 10.1016/j.wasman.2018.12.024 |
Waste Management 85 | 2019-11-22 |
| 2019 |
Natalia A. Tarazona, Beatriz Maestro, Olga Revelles, Jesús M. Sanz, M. Auxiliadora Prieto Role of leucine zipper-like motifs in the oligomerization of Pseudomonas putida phasins published pages: 362-370, ISSN: 0304-4165, DOI: 10.1016/j.bbagen.2018.11.002 |
Biochimica et Biophysica Acta (BBA) - General Subjects 1863/2 | 2019-11-22 |
| 2019 |
Aranzazu Mato, Natalia A. Tarazona, Alberto Hidalgo, Antonio Cruz, Mercedes Jiménez, Jesús Pérez-Gil, M. Auxiliadora Prieto Interfacial Activity of Phasin PhaF from Pseudomonas putida KT2440 at Hydrophobic–Hydrophilic Biointerfaces published pages: 678-686, ISSN: 0743-7463, DOI: 10.1021/acs.langmuir.8b03036 |
Langmuir 35/3 | 2019-11-22 |
| 2018 |
Alexander P. S. Darlington, Juhyun Kim, José I. Jiménez, Declan G. Bates Engineering Translational Resource Allocation Controllers: Mechanistic Models, Design Guidelines, and Potential Biological Implementations published pages: , ISSN: 2161-5063, DOI: 10.1021/acssynbio.8b00029 |
ACS Synthetic Biology | 2019-11-22 |
| 2017 |
Rohola Hosseini, Jannis Kuepper, Sebastian Koebbing, Lars M. Blank, Nick Wierckx, Johannes H. de Winde Regulation of solvent tolerance in Pseudomonas putida S12 mediated by mobile elements published pages: n.a., ISSN: 1751-7915, DOI: 10.1111/1751-7915.12495 |
Microbial Biotechnology n.a. | 2019-11-22 |
| 2018 |
Alexander P. S. Darlington, Juhyun Kim, José I. Jiménez, Declan G. Bates Dynamic allocation of orthogonal ribosomes facilitates uncoupling of co-expressed genes published pages: 695, ISSN: 2041-1723, DOI: 10.1038/s41467-018-02898-6 |
Nature Communications 9/1 | 2019-11-22 |
| 2018 |
Audrey Magnin, Lucie Hoornaert, Eric Pollet, Stéphanie Laurichesse, Vincent Phalip, Luc Avérous Isolation and characterization of different promising fungi for biological waste management of polyurethanes published pages: 1-12, ISSN: 1751-7915, DOI: 10.1111/1751-7915.13346 |
Microbial Biotechnology | 2019-11-22 |
| 2018 |
Christian Eberlein, Thomas Baumgarten, Stephan Starke, Hermann J. Heipieper Immediate response mechanisms of Gram-negative solvent-tolerant bacteria to cope with environmental stress: cis-trans isomerization of unsaturated fatty acids and outer membrane vesicle secretion published pages: 2583-2593, ISSN: 0175-7598, DOI: 10.1007/s00253-018-8832-9 |
Applied Microbiology and Biotechnology 102/6 | 2019-11-22 |
| 2017 |
Tanja Narancic, Kevin E. O\'Connor Microbial biotechnology addressing the plastic waste disaster published pages: NA, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12775 |
Microbial Biotechnology | 2019-11-22 |
| 2016 |
J. Kim, M. Salvador, E. Saunders, J. Gonzalez, C. Avignone-Rossa, J. I. Jimenez Properties of alternative microbial hosts used in synthetic biology: towards the design of a modular chassis published pages: 303-313, ISSN: 0071-1365, DOI: 10.1042/EBC20160015 |
Essays In Biochemistry 60/4 | 2019-11-22 |
| 2017 |
Lars M. Blank Let\'s talk about flux or the importance of (intracellular) reaction rates published pages: 28-30, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12455 |
Microbial Biotechnology 10/1 | 2019-11-22 |
| 2017 |
Matteo Cavaliere, Song Feng, Orkun Soyer, Jose I. Jimenez Cooperation in microbial communities and their biotechnological applications published pages: 2949-2963, ISSN: 1462-2912, DOI: 10.1111/1462-2920.13767 |
Environmental Microbiology 19(8) | 2019-11-22 |
| 2016 |
Auxiliadora Prieto To be, or not to be biodegradable… that is the question for the bio-based plastics published pages: 652-657, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12393 |
Microbial Biotechnology 9/5 | 2019-11-22 |
| 2015 |
Sebastian Zobel, Ilaria Benedetti, Lara Eisenbach, Victor de Lorenzo, Nick Wierckx, Lars M. Blank Tn7-Based Device for Calibrated Heterologous Gene Expression in Pseudomonas putida published pages: 1341-1351, ISSN: 2161-5063, DOI: 10.1021/acssynbio.5b00058 |
ACS Synthetic Biology 4/12 | 2019-11-22 |
| 2017 |
Jose Ignacio Jiménez Shedding light on the black box models of the cell published pages: 43-45, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12489 |
Microbial Biotechnology 10 | 2019-11-22 |
| 2017 |
Ren Wei, Wolfgang Zimmermann Biocatalysis as a green route for recycling the recalcitrant plastic polyethylene terephthalate published pages: 6, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12714 |
Microbial Biotechnology Vol. 10, 2017 | 2019-11-22 |
| 2017 |
Ren Wei, Wolfgang Zimmermann Microbial enzymes for the recycling of recalcitrant petroleum-based plastics: how far are we? published pages: , ISSN: 1751-7915, DOI: 10.1111/1751-7915.12710 |
Microbial Biotechnology Vol. 10, 2017 | 2019-11-22 |
| 2015 |
Nick Wierckx, M. Auxiliadora Prieto, Pablo Pomposiello, Victor de Lorenzo, Kevin O\'Connor, Lars M. Blank Plastic waste as a novel substrate for industrial biotechnology published pages: 900-903, ISSN: 1751-7915, DOI: 10.1111/1751-7915.12312 |
Microbial Biotechnology 8/6 | 2019-11-22 |
| 2016 |
Köbbing, Sebastian; Wynands, Benedikt Niklas Daniel; Blank, Lars Mathias; Wierckx, Nick Synthetic promoter libraries, a powerful tool for tuning gene expression published pages: , ISSN: , DOI: |
3rd Congress on Applied Synthetic Biology in Europe, Lisbon, Portugal, 2016-02-22 - 2016-02-24 1 | 2019-11-22 |
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