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FLDcure

A potent Micro-RNA therapeutic for nonalcoholic fatty liver disease (NAFLD)

Total Cost €

EC-Contrib. €

Partnership

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FLDcure project word cloud

Explore the words cloud of the FLDcure project. It provides you a very rough idea of what is the project "FLDcure" about.

encourage cirrhosis treatment fatty trials progress reduce liver dramatically pharmaceutical therapeutic microrna fld perportion benefits steatohepatitis pathogenesis agent pursue disease license population mouse huge company nonalcoholic health prompt shown extend cancer clinical model

Project "FLDcure" data sheet

The following table provides information about the project.

Coordinator	THE HEBREW UNIVERSITY OF JERUSALEM Organization address address: EDMOND J SAFRA CAMPUS GIVAT RAM city: JERUSALEM postcode: 91904 website: www.huji.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Israel [IL]
Total cost	149˙800 €
EC max contribution	149˙800 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2014-PoC
Funding Scheme	ERC-POC
Starting year	2015
Duration (year-month-day)	from 2015-01-01 to 2016-06-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE HEBREW UNIVERSITY OF JERUSALEM THE HEBREW UNIVERSITY OF JERUSALEM Organization address address: EDMOND J SAFRA CAMPUS GIVAT RAM city: JERUSALEM postcode: 91904 website: www.huji.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (JERUSALEM)	coordinator	149˙800.00

Map

Project objective

Fatty Liver disease (FLD) is a widespread disease which can often progress to Nonalcoholic steatohepatitis, cirrhosis and liver cancer. At present FLD disease affects a huge perportion of the population and prompt treatment will be of major health benefits to the general population. We have developed a specific therapeutic targeting a microRNA we and others have shown to be involved in the pathogenesis of FLD. This therapeutic agent can dramatically reduce FLD in a mouse model. We would like to extend the pre-clinical studies in order to encourage interest of a pharmaceutical company who will license the technology and pursue clinical trials.

Publications

List of publications.
year	authors and title	journal	last update
2016	Shani Shenhar-Tsarfaty Itzhak Shapira Sharon Toker Ori Rogowski Shlomo Berliner , Yaacov Ritovd and Hermona Soreqa1 Weakened Cholinergic Blockade of Inflammation Associates with DiabetesRelatedDepression published pages: , ISSN: 1076-1551, DOI: 10.2119/molmed	Molecular Medicine 2016 Apr 4;22	2019-07-22

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The information about "FLDCURE" are provided by the European Opendata Portal: CORDIS opendata.