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TRANSFORMER SIGNED

Transformation of emerging contaminants in the aquatic environment. Fate of transformation products under multiple stress conditions

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

TRANSFORMER project word cloud

Explore the words cloud of the TRANSFORMER project. It provides you a very rough idea of what is the project "TRANSFORMER" about.

permit compounds artificial time entrance transformations environmental pharmaceuticals abiotic water flow tps transformer stream drought environments identification innovative tp profile prerequisite inland class special spectrometric transformed phacs metabolism facility photodegradation active sediment once biological mechanisms simultaneous coefficients understudied therapeutics biodegradation accordingly plan adsorption photolysis temperature undergo thorough rivers environment proposes photo desorption instrumentation transformation icra fluctuations experimental resolution terrestrial substantial sorption formed vs attenuation risk partition aquatic hybrid first contaminants biotic societal biofilm situations light elucidation peptide mass intermittent peptidomimetics pharmaceutically

Project "TRANSFORMER" data sheet

The following table provides information about the project.

Coordinator	FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA Organization address address: CALLE EMILI GRAHIT EDIFICI H20 101 city: GIRONA postcode: 17003 website: http://icra.udg.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Total cost	106˙326 €
EC max contribution	106˙326 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-EF-ST
Starting year	2015
Duration (year-month-day)	from 2015-05-11 to 2016-08-10

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA FUNDACIO INSTITUT CATALA DE RECERCA DE L'AIGUA Organization address address: CALLE EMILI GRAHIT EDIFICI H20 101 city: GIRONA postcode: 17003 website: http://icra.udg.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (GIRONA)	coordinator	106˙326.00

Map

Project objective

Pharmaceutically active compounds (PhACs) are a special class of contaminants because they can undergo transformations through metabolism before their entrance into aquatic and terrestrial environments. Once they reach the environment they are further transformed by abiotic and/or biotic transformation processes and understanding of transformation pathways and identification of transformation products (TP) is a prerequisite for a thorough assessment of their environmental risk. This project proposes the use of Experimental Stream Facility (artificial rivers), a unique facility available at ICRA that will permit simultaneous study of biodegradation, photolysis, and adsorption /desorption processes under different situations, such as intermittent flow (drought), temperature or light fluctuations, among others. State of the art hybrid and high resolution mass spectrometric instrumentation will be used to study transformation pathways and provide a comprehensive and detailed profile of TPs formed. By using an integrated approach and simultaneous study of biotic and abiotic transformation processes TRANSFORMER’s main expected results are: (i) elucidation of transformation pathways (biological and photo induced) and identification of main TPs from a number of relevant pharmaceuticals (including some understudied and, for the first time, a new class pharmaceuticals such as peptidomimetics and peptide therapeutics); (ii) determination of partition coefficients (water-sediment and water-biofilm) of the studied pharmaceuticals and TPs and (iii) identification of potential controlling factors and mechanisms behind in-stream attenuation of pharmaceuticals (biodegradation vs photodegradation vs sorption). Accordingly, we expect that the results produced by this innovative research plan will have substantial impact on the field of inland water research, one of the Europe’s Societal Challenges.

Publications

List of publications.
year	authors and title	journal	last update
2016	Marko RoÅ¾man, Mira PetroviÄ‡ Bquant â€“ Novel script for batch quantification of LCMS data published pages: 520-524, ISSN: 2215-0161, DOI: 10.1016/j.mex.2016.09.001	MethodsX 3	2019-06-13

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The information about "TRANSFORMER" are provided by the European Opendata Portal: CORDIS opendata.