Explore the words cloud of the PHOTONET-C4 project. It provides you a very rough idea of what is the project "PHOTONET-C4" about.
The following table provides information about the project.
Coordinator |
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://www.stevekellylab.com |
Total cost | 1˙482˙363 € |
EC max contribution | 1˙482˙363 € (100%) |
Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
Code Call | ERC-2014-STG |
Funding Scheme | ERC-STG |
Starting year | 2015 |
Duration (year-month-day) | from 2015-11-01 to 2020-10-31 |
Take a look of project's partnership.
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1 | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD | UK (OXFORD) | coordinator | 1˙482˙363.00 |
Photosynthesis underpins life on earth. Despite its fundamental importance, our knowledge of the molecular regulators that control the expression of photosynthetic genes is limited, and only four transcription factors are known to regulate the expression of cohorts of photosynthetic genes in plants.
This project aims to address this knowledge gap by identifying and characterising the molecular regulators that control the expression of photosynthetic genes. This aim will be achieved through an innovative high-throughput strategy that exploits a naturally occurring cellular subdivision of photosynthesis, known as C4 photosynthesis, that has evolved independently in over 60 different plant lineages.
Using two species that represent independent origins of C4 (Setaria italica and Sorghum bicolor) and two related C3 species (Oryza sativa and Dichanthelium oligosanthes) the aims of this project will be achieved through the following objectives:
1) In each of the four species, characterise the DNA binding motifs of 100 (orthologous) transcription factors that are differentially regulated in the C4 species. 2) Identify candidate transcription factors whose targets are photosynthetic genes through comparative bioinformatic approaches.
3) Overexpress candidate transcription factors in rice (C3) and validate the downstream targets using transcriptomic approaches.
My combined expertise in molecular biology and bioinformatics puts me in an excellent position to deliver this project and identify the transcription factors that regulate photosynthesis in plants. By focusing on C4 photosynthesis, this project will provide fundamental insight into both plant evolution and the regulation of photosynthesis. Moreover, it will accelerate international efforts that aim to introduce C4 traits into globally important C3 crops such as rice and wheat.
year | authors and title | journal | last update |
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2018 |
de Freitas Nascimento, Janaina; Kelly, Steven; Sunter, Jack; Carrington, Mark Codon choice directs constitutive mRNA levels in trypanosomes published pages: , ISSN: 2050-084X, DOI: 10.17863/CAM.23265 |
eLife 2 | 2019-05-29 |
2016 |
David M. Emms, Sarah Covshoff, Julian M. Hibberd, Steven Kelly Independent and Parallel Evolution of New Genes by Gene Duplication in Two Origins of C4 Photosynthesis Provides New Insight into the Mechanism of Phloem Loading in C4 Species published pages: 1796-1806, ISSN: 0737-4038, DOI: 10.1093/molbev/msw057 |
Molecular Biology and Evolution 33/7 | 2019-05-29 |
2016 |
Bruno Catarino, Alexander J. Hetherington, David M. Emms, Steven Kelly, Liam Dolan The Stepwise Increase in the Number of Transcription Factor Families in the Precambrian Predated the Diversification of Plants On Land published pages: 2815-2819, ISSN: 0737-4038, DOI: 10.1093/molbev/msw155 |
Molecular Biology and Evolution 33/11 | 2019-05-29 |
2018 |
Florence R Danila, William Paul Quick, Rosemary G White, Steven Kelly, Susanne von Caemmerer, Robert T Furbank Multiple mechanisms for enhanced plasmodesmata density in disparate subtypes of C4 grasses published pages: 1135-1145, ISSN: 0022-0957, DOI: 10.1093/jxb/erx456 |
Journal of Experimental Botany 69/5 | 2019-05-29 |
2016 |
Ellis C. O’Neill, Steven Kelly Engineering biosynthesis of high-value compounds in photosynthetic organisms published pages: 1-24, ISSN: 0738-8551, DOI: 10.1080/07388551.2016.1237467 |
Critical Reviews in Biotechnology | 2019-05-29 |
2017 |
Emms, DM; Kelly, S STRIDE: Species Tree Root Inference from Gene Duplication Events. published pages: , ISSN: 1537-1719, DOI: 10.1101/140020 |
Molecular Biology and Evolution 5 | 2019-05-29 |
2018 |
Steven Kelly The Amount of Nitrogen Used for Photosynthesis Modulates Molecular Evolution in Plants published pages: 1616-1625, ISSN: 0737-4038, DOI: 10.1093/molbev/msy043 |
Molecular Biology and Evolution 35/7 | 2019-05-29 |
2016 |
Suvi Honkanen, Victor A.S. Jones, Giulia Morieri, Clement Champion, Alexander J. Hetherington, Steve Kelly, Hélène Proust, Denis Saint-Marcoux, Helen Prescott, Liam Dolan The Mechanism Forming the Cell Surface of Tip-Growing Rooting Cells Is Conserved among Land Plants published pages: 3238-3244, ISSN: 0960-9822, DOI: 10.1016/j.cub.2016.09.062 |
Current Biology 26/23 | 2019-05-29 |
2016 |
C. A. Brackley, D. Michieletto, F. Mouvet, J. Johnson, S. Kelly, P. R. Cook, D. Marenduzzo Simulating topological domains in human chromosomes with a fitting-free model published pages: 453-461, ISSN: 1949-1034, DOI: 10.1080/19491034.2016.1239684 |
Nucleus 7/5 | 2019-05-29 |
2018 |
Michael P. Dunne, Steven Kelly OMGene: mutual improvement of gene models through optimisation of evolutionary conservation published pages: , ISSN: 1471-2164, DOI: 10.1186/s12864-018-4704-z |
BMC Genomics 19/1 | 2019-05-29 |
2018 |
Friederike Grosse-Holz, Steven Kelly, Svenja Blaskowski, Farnusch Kaschani, Markus Kaiser, Renier A.L. van der Hoorn The transcriptome, extracellular proteome and active secretome of agroinfiltrated Nicotiana benthamiana uncover a large, diverse protease repertoire published pages: 1068-1084, ISSN: 1467-7644, DOI: 10.1111/pbi.12852 |
Plant Biotechnology Journal 16/5 | 2019-05-29 |
2017 |
Steven Kelly, Alasdair Ivens, G. Adam Mott, Ellis O’Neill, David Emms, Olivia Macleod, Paul Voorheis, Kevin Tyler, Matthew Clark, Jacqueline Matthews, Keith Matthews, Mark Carrington An Alternative Strategy for Trypanosome Survival in the Mammalian Bloodstream Revealed through Genome and Transcriptome Analysis of the Ubiquitous Bovine Parasite Trypanosoma (Megatrypanum) theileri published pages: 2093-2109, ISSN: 1759-6653, DOI: 10.1093/gbe/evx152 |
Genome Biology and Evolution 9/8 | 2019-05-29 |
2017 |
Michael P. Dunne, Steven Kelly OrthoFiller: utilising data from multiple species to improve the completeness of genome annotations published pages: , ISSN: 1471-2164, DOI: 10.1186/s12864-017-3771-x |
BMC Genomics 18/1 | 2019-05-29 |
2016 |
Emily A. Seward, Steven Kelly Dietary nitrogen alters codon bias and genome composition in parasitic microorganisms published pages: , ISSN: 1474-760X, DOI: 10.1186/s13059-016-1087-9 |
Genome Biology 17/1 | 2019-05-29 |
2016 |
Richard Smith-Unna, Chris Boursnell, Rob Patro, Julian M. Hibberd, Steven Kelly TransRate: reference-free quality assessment of de novo transcriptome assemblies published pages: 1134-1144, ISSN: 1088-9051, DOI: 10.1101/gr.196469.115 |
Genome Research 26/8 | 2019-05-29 |
2018 |
Emily A. Seward, Steven Kelly Selection-driven cost-efficiency optimization of transcripts modulates gene evolutionary rate in bacteria published pages: , ISSN: 1474-760X, DOI: 10.1186/s13059-018-1480-7 |
Genome Biology 19/1 | 2019-05-29 |
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The information about "PHOTONET-C4" are provided by the European Opendata Portal: CORDIS opendata.