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COBIOPHAD

COMPACT BIOPHOTONIC PLATFORM FOR DRUG ALLERGY DIAGNOSIS

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

COBIOPHAD project word cloud

Explore the words cloud of the COBIOPHAD project. It provides you a very rough idea of what is the project "COBIOPHAD" about.

reactions blcs mediated 4500 additional vitro drugs daily compact telecom allergen antibiotics building lt cobiophad biotechnology diagnostic actors million vivo safety solution multiplexed health ameliorate microstructures single tests lack gt 98 market electronics hypersensitivity selective beta invasive drug selectivity manufacturing placing microfluidics diagnosis risky adverse biophotonic organic sensitivity min kua 1750 ing patient sensitive mainly consuming multidisciplinary device 35 ivd lactams industrial inaccurate few expensive disc surface hospitalization citizens allergies optics 180 services networking time technologies rapid innovative analyze preventable materials ige smart assays chemistry tertiary allergens allergy

Project "COBIOPHAD" data sheet

The following table provides information about the project.

Coordinator	UNIVERSITAT POLITECNICA DE VALENCIA Organization address address: CAMINO DE VERA SN EDIFICIO 3A city: VALENCIA postcode: 46022 website: www.upv.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.cobiophad.eu
Total cost	4˙288˙094 €
EC max contribution	3˙734˙780 € (87%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2015
Funding Scheme	IA
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-07-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	UNIVERSITAT POLITECNICA DE VALENCIA UNIVERSITAT POLITECNICA DE VALENCIA Organization address address: CAMINO DE VERA SN EDIFICIO 3A city: VALENCIA postcode: 46022 website: www.upv.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	coordinator	1˙026˙678.00
2	STIFTELSEN SINTEF STIFTELSEN SINTEF Organization address address: STRINDVEIEN 4 city: TRONDHEIM postcode: 7034 website: www.sintef.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (TRONDHEIM)	participant	462˙945.00
3	CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER CENTRE HOSPITALIER UNIVERSITAIRE MONTPELLIER Organization address address: AVENUE DU DOYEN GASTON GIRAUD 191 city: MONTPELLIER postcode: 34000 website: www.chu-montpellier.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (MONTPELLIER)	participant	451˙932.00
4	FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA FUNDACION PARA LA INVESTIGACION DEL HOSPITAL UNIVERSITARIO LA FE DE LA COMUNIDAD VALENCIANA Organization address address: AV FERNANDO ABRIL MARTORELL 106 city: VALENCIA postcode: 46026 website: http://www.iislafe.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	participant	364˙687.00
5	DR. FOOKE-ACHTERRATH LABORATORIEN GMBH DR. FOOKE-ACHTERRATH LABORATORIEN GMBH Organization address address: HABICHTWEG 16 city: NEUSS postcode: 41468 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (NEUSS)	participant	314˙978.00
6	STRATEC CONSUMABLES GMBH STRATEC CONSUMABLES GMBH Organization address address: SONYSTRASSE 20 city: ANIF postcode: 5081 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (ANIF)	participant	304˙097.00
7	BIOTRONICS 3D LIMITED BIOTRONICS 3D LIMITED Organization address address: 5 GREENWICH VIEW PLACE CITY REACH THIRD FLOOR SUITE D city: LONDON postcode: E14 9NN website: www.biotronics3d.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	211˙596.00
8	OPTOELECTRONICA - 2001 SA OPTOELECTRONICA - 2001 SA Organization address address: BD TUDOR VLADIMIRESCU 22 GREEN GATE OFFICES FL 8 city: BUCHAREST postcode: 50880 website: www.optoel.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	RO (BUCHAREST)	participant	159˙300.00
9	EUREXPLOIT LTD EUREXPLOIT LTD Organization address address: 78 MILL LANE city: LONDON postcode: NW6 1JZ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	153˙128.00
10	SINTEF AS SINTEF AS Organization address address: STRINDVEGEN 4 city: TRONDHEIM postcode: 7034 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (TRONDHEIM)	participant	137˙475.00
11	LUMENSIA SENSORS SL LUMENSIA SENSORS SL Organization address address: CAMINO DE VERA S/N, PLANTA 2, BUILDING 8 city: VALENCIA postcode: 46022 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	participant	76˙733.00
12	DAS PHOTONICS SL DAS PHOTONICS SL Organization address address: CALLE ISLAS CANARIAS, 6 - 8 city: VALENCIA postcode: 46023 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	participant	38˙854.00
13	SONY DADC AUSTRIA SONY DADC AUSTRIA Organization address address: SONYSTRASSE 20 city: ANIF postcode: 5081 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (ANIF)	participant	32˙373.00

Map

Project objective

Drug hypersensitivity to antibiotics, mainly Beta-lactams (BLCs) affects more than 2.5 million European citizens. Moreover, preventable adverse drug reactions are estimated in additional hospitalization costs of 1750-4500 €/patient. Currently, the allergy diagnosis is mainly based on the information given by invasive, single, and risky in vivo assays. In daily practice, few in vitro diagnostic methods are available and only used at the tertiary health services. These tests also lack of sensitivity (>0.35 kUA/L) and selectivity (<98%), resulting in an inaccurate diagnosis, analyze few drugs allergens (5), are time consuming (60-180 min), and expensive (30 €/allergen).

COBIOPHAD aims the development of an innovative in vitro diagnostic (IVD) device for diagnosis of IgE-mediated drug allergies by building an integrated biophotonic system based on compact disc technology. For that, key enabling technologies will be integrated in order to achieve high sensitive (<0.1 kUA/L), selective (>98%), multiplexed (10 BLCs), rapid (30 min), and low-cost (2.4 €/allergen) drug allergy test. The solution involves an advanced approach to the diagnosis and management of drug allergy with the aim to ameliorate patient safety.

The consortium comprises multidisciplinary knowledge on optics, electronics, advanced materials, biotechnology, smart microstructures, microfluidics, surface/organic chemistry, allergy, manufacturing systems, and telecom networking. Also, the key industrial actors, present in the consortium, will contribute to the manufacturing and placing the product on the IVD market.

Deliverables

List of deliverables.
Final Communication kit about the project	Websites, patent fillings, videos etc.	2020-01-29 12:43:06
New diagnostic device (COBIOPHAD) characteristics and performances	Documents, reports	2020-01-29 12:43:06
Work-up of new international recommendations for the patient allergy medical care	Documents, reports	2020-01-29 12:43:06
Short film magazine	Websites, patent fillings, videos etc.	2020-01-29 12:43:06
Report on integration and assays testing	Documents, reports	2020-01-29 12:43:06
Technical dossier including the analysis of the compliance with the defined requirements	Documents, reports	2020-01-29 12:43:06
First Communication kit about the project	Websites, patent fillings, videos etc.	2020-01-29 12:43:05
Web site	Websites, patent fillings, videos etc.	2020-01-29 12:43:06
Second Communication kit about the project	Websites, patent fillings, videos etc.	2020-01-29 12:43:06
Project presentation	Websites, patent fillings, videos etc.	2020-01-29 12:43:06

Take a look to the deliverables list in detail: detailed list of COBIOPHAD deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	Dr Ian A. McKay COBIOPHAD MAGAZINE published pages: , ISSN: , DOI:		2020-01-29
2019	Elizaveta Vereshchagina, Sergi Morais, Luis A. Tortajada-Genaro, Angel Maquieira, Estrella Fernandez, Teresa Molina, Veaceslav Linte, Brindus Comanescu, Michal M. Mielnik, Erik Andreassen, Anna Franquesa-Vazquez, Werner Balika5, Alfredo SÃ¡ez, Sergio Peransi Llopis A NOVEL DIAGNOSTIC DEVICE FOR RAPID TESTING OF ANTIBIOTIC ALLERGIES: FOCUS ON FLUIDIC DESIGN AND MANUFACTURING OF DISPOSABLE DISCS published pages: , ISSN: , DOI:		2020-01-29
2016	A. Maquierira ÃŸ-lactams antibiotics allergy published pages: 212-213, ISSN: 2054-2631, DOI:	HORIZON 2020 PROJECTS: PORTAL 10 April 2016	2020-01-29
2016	N. Offermann, M. Plum, U. HÃ¼bner, K. Rathloff, I. Braren, M. Fooke, E. Spillner Human serum substitution by artificial sera of scalable allergen reactivity based on polyclonal antibodies and chimeras of human FcÎ³RI and IgE domains published pages: 1794-1799, ISSN: 0105-4538, DOI: 10.1111/all.13038	Allergy 71/12	2020-01-29
2017	E.Vereshchagina, M.Mielnik, E.Andreassen Written by I.RambÃ¦k Tryggere antibiotikabruk med ny allergitest (Norwegian)New allergy test promises safer antibiotic use (English) published pages: , ISSN: 0802-085X, DOI:	Gemini	2020-01-29
2017	E. Vereshchagina, E. Andreassen, R.H. Gaarder, M.M. Mielnik SYNERGY OF 3D PRINTING AND INJECTION MOLDING: A NEW PROTOTYPING METHOD FOR RAPID DESIGN OPTIMIZATION AND MANUFACTURING OF MICROFLUIDIC DEVICES published pages: , ISSN: , DOI:	Proceedings of the The 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (Microtas17) Annual	2020-01-29

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The information about "COBIOPHAD" are provided by the European Opendata Portal: CORDIS opendata.