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ALGAE4A-B SIGNED

Development of Microalgae-based novel high added-value products for the Cosmetic and Aquaculture industry

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

ALGAE4A-B project word cloud

Explore the words cloud of the ALGAE4A-B project. It provides you a very rough idea of what is the project "ALGAE4A-B" about.

technologies strategic commercial optimize transfer cosmetic algae biochemistry sustainable microalgae compounds source diversification academic aquaculture apart cosmetics training untapped seas aspires emphasis beauty culture always vitro proteins biomolecules reservoir gain nutraceutical omic efficient tools added scientific industrial blue algae4a building omics analytical fast polysaccharides changing biotechnology input coasts markets formulate harness platform bioactive capacity fishes environment industry downstream opportunity biomass enzymes largely uncertain marine combine translate antioxidants competitive multidisciplinary alternative valuable basic diversity society independent

Project "ALGAE4A-B" data sheet

The following table provides information about the project.

Coordinator	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	http://www.algae4ab.eu
Total cost	972˙000 €
EC max contribution	972˙000 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	coordinator	27˙000.00
2	FITOPLANCTON MARINO, S.L. FITOPLANCTON MARINO, S.L. Organization address address: Darsena comercial s/n (Muelle Pesquero) city: EL PUERTO DE SANTA MARIA postcode: 11500 website: www.easyalgae.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (EL PUERTO DE SANTA MARIA)	participant	234˙000.00
3	GEOPONIKO PANEPISTIMION ATHINON GEOPONIKO PANEPISTIMION ATHINON Organization address address: IERA ODOS 75 city: ATHINA postcode: 118 55 website: www.aua.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	225˙000.00
4	APIVITA KALLYNTIKA DIAITITIKA FARMAKA ANONYMI EMPORIKI KAI VIOTECHNIKI ETAIREIA APIVITA KALLYNTIKA DIAITITIKA FARMAKA ANONYMI EMPORIKI KAI VIOTECHNIKI ETAIREIA Organization address address: INDUSTRIAL PARK OF MARKOPOULO city: MARKOPOULO postcode: 19003 website: www.apivita.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (MARKOPOULO)	participant	216˙000.00
5	CENTRO DE CIENCIAS DO MAR DO ALGARVE CENTRO DE CIENCIAS DO MAR DO ALGARVE Organization address address: UNIVERSIDADE DO ALGARVE city: FARO postcode: 8005 032 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PT (FARO)	participant	108˙000.00
6	INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA INSTITUTO ANDALUZ DE INVESTIGACIONY FORMACION AGRARIA PESQUERA ALIMENTARIA Y DE LA PRODUCCION ECOLOGICA Organization address address: AVENIDA GRECIA S/N EDF ATVO LOS BERMEJALES city: SEVILLA postcode: 41012 website: www.ifapa.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (SEVILLA)	participant	81˙000.00
7	LIFESEQUENCING SL LIFESEQUENCING SL Organization address address: C CATEDRATICO DR D AGUSTIN ESCARDINO BENLLOCH 9 PARQUE CIENTIFICO DE LA UNIVERSIDAD DE VALENCIA city: PATERNA postcode: 46980 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (PATERNA)	participant	81˙000.00

Map

Project objective

Microalgae were always an exciting target for Aquaculture and Biotechnology, as they represent a largely untapped reservoir of novel and valuable bioactive compounds. ALGAE4A-B (ALGAE For Aquaculture and Beauty) project seeks to exploit the microalgae diversity, as a source for state-of-the art high-added-value biomolecules in aquaculture and cosmetics. The diversification of microalgae biomass production towards two independent applications will allow the microalgae industry to gain access to alternative markets in an uncertain, highly competitive and fast changing commercial environment. The project will combine both basic and applied multidisciplinary research in the fields of –omics technologies, biochemistry and applied biotechnology in order to: a) Develop and optimize of low input and application-based microalgae culture systems, b) Develop of “-omic” resources for both microalgae and fishes, c) Develop of downstream processing of high value added products from microalgae, with an emphasis in polysaccharides, proteins, enzymes, antioxidants, d) Develop, formulate and in vitro evaluate a new range of cosmetic and nutraceutical products for aquaculture. The implementation of the project will offer the industrial partners the opportunity to translate scientific research into well defined knowledge-based end products and analytical tools. Apart from scientific objectives the ALGAE4A-B will provide a platform for an efficient dissemination, transfer of knowledge and training between academic, commercial partners and society. Overall, ALGAE4A-B aspires to foster both the European capacity building and the strategic objectives of EU Blue Growth and Marine Biotechnology to harness the untapped potential of Europe's seas and coasts for training and sustainable growth.

Deliverables

List of deliverables.
Final project evaluation and assessment report	Documents, reports	2020-03-24 13:09:37
Progress reports and project evaluation and assessment reports	Documents, reports	2020-03-24 13:09:32
Intellectual property and networking activities report	Documents, reports	2020-03-24 13:09:35
Report on outreach activities to the general public	Documents, reports	2020-03-24 13:09:39
Publications in scientific journals/conferences	Other	2020-03-24 13:09:36
Detailed report on the training and transfer of knowledge obtained through the secondments	Documents, reports	2020-03-13 11:19:22
Report on the quality control of the cosmeceutical products	Documents, reports	2020-03-13 11:19:16
Establish the main biological effects of novel nutraceuticals on fish performance	Documents, reports	2020-03-13 11:19:00
Purification and structural analysis of selected algae polysaccharides	Documents, reports	2020-03-13 10:23:04
A downstream processing protocol for enzymes purification	Documents, reports	2020-03-13 10:23:04
Establish protocols for nutraceuticals administration	Documents, reports	2020-03-13 10:23:03
Purification and characterization of hatching enzyme	Documents, reports	2020-03-13 10:23:04
Steady-state kinetic characterization of enzymes and thermodynamics analysis of the enzyme stability	Documents, reports	2020-03-13 10:23:05
Define the ontogeny of immune barriers and effects of nutraceuticals	Documents, reports	2020-03-13 11:19:08
Optimal conditions of light intensity	Documents, reports	2020-03-11 13:05:56
Stimulation of growth by methanol	Documents, reports	2020-03-11 14:34:51
Mapping bioactive properties using in vitro enzyme bioassays	Documents, reports	2020-03-11 13:05:41
Glycomic profile of microalgae under different culture regimes	Documents, reports	2020-03-11 13:05:41
Optimization of growth under various growth media	Documents, reports	2020-03-11 13:05:56
Transcriptome associated with novel bioactive products in fish	Documents, reports	2020-03-11 14:46:35
Progress report Month 36	Documents, reports	2020-03-11 14:34:39
Catalomic profile of microalgae under different culture regimes	Documents, reports	2020-03-11 14:45:42
Minutes of all managements meetings held	Documents, reports	2020-03-11 14:34:50
Development of a fish epithelial model and assessment of toxicity and impact on the transcriptome and enzyme activities of microalgal extracts	Documents, reports	2020-03-11 13:05:55
Optimal conditions of photonic quality	Documents, reports	2020-03-11 14:34:40
Analytical Handbook	Other	2020-03-11 14:34:51
Identification and characterization of high-value added enzymes (proteases, lipases and antioxidant enzymes) with potential applications in cosmetology	Documents, reports	2020-03-11 13:05:56
In vitro toxicity assessments of microalgae extracts or compounds	Documents, reports	2020-03-11 13:05:55
Transcriptome associated with novel bioactive products in microalgae	Documents, reports	2020-03-11 14:45:42
Proceedings of the Summer schools	Documents, reports	2020-03-11 14:34:50
Comparative model of human and fish keratinocyte response to microalgal extracts	Documents, reports	2020-03-11 13:05:54
Transfer of the optimal growth conditions from lab scale to the large scale photobioreactors	Documents, reports	2020-03-11 14:34:51
Metabolomic profile of microalgae under different culture regimes	Documents, reports	2020-03-11 13:05:38
Biannual e-newsletters	Other	2020-03-11 14:34:51
Proceedings of the training workshops	Documents, reports	2020-03-11 14:34:50
Report on the effect of microalgae extracts or compounds on the transcription of skin-related genes using human cell lines.	Documents, reports	2020-03-11 13:05:54
ALGAE4A-B Project Website	Websites, patent fillings, videos etc.	2020-01-29 12:55:50
Training and e-learning web-site	Websites, patent fillings, videos etc.	2020-01-29 12:55:50
Progress report Month 12	Documents, reports	2020-01-29 12:55:50

Take a look to the deliverables list in detail: detailed list of ALGAE4A-B deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2020	Maria Patelou, Carlos Infante, Flavien Dardelle, DÃ¶rte Randewig, Evangelia D. Kouri, Michael K. Udvardi, Eleni Tsiplakou, Lalia MantecÃ³n, Emmanouil Flemetakis Transcriptomic and metabolomic adaptation of Nannochloropsis gaditana grown under different light regimes published pages: 101735, ISSN: 2211-9264, DOI: 10.1016/j.algal.2019.101735	Algal Research 45	2020-02-28
2020	Sophia Letsiou, Rute Felix, JoÃ£o C. Cardoso, Liliana Anjos, Ana L. Mestre, Henirique L. Gomes, Deborah M. Power Cartilage acidic protein 1 promotes increased cell viability, cell proliferation and energy metabolism in primary human dermal fibroblasts published pages: , ISSN: 0300-9084, DOI: 10.1016/j.biochi.2020.02.008	Biochimie	2020-02-28
2018	Manuel Manchado Genomic and epigenetic advances in sole aquaculture published pages: , ISSN: , DOI:		2020-02-28
2019	Carlos Carballo, Patricia I.S. Pinto, Ana Patricia Mateus, Concha Berbel, ClÃ¡udia C. Guerreiro, Juan F. Martinez-Blanch, Francisco M. CodoÃ±er, Lalia Mantecon, Deborah M. Power, Manuel Manchado Yeast Î²-glucans and microalgal extracts modulate the immune response and gut microbiome in Senegalese sole (Solea senegalensis) published pages: 31-39, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2019.05.044	Fish & Shellfish Immunology 92	2020-02-28
2018	Pinto PIS, Guerreiro C, Costa RA, Martinez-Blanch JF, Carballo C, CodoÃ±er F, Manchado M, Power DM Omics signatures of pseudo-albino in Senegalese sole published pages: , ISSN: , DOI:	VII Congress of the Iberian Soc. for Ichthyology	2020-02-28
2019	P. Pinto (CCMAR) The use of fish mineralized tissues to assess estrogenic endocrine disruption and other ongoing transcriptome and microbiome studies at CCMAR (including Algae4ab) published pages: , ISSN: , DOI:	Invited talk at research centre UMR I-02 SEBIO, University le Havre-Normandie (France)	2020-02-28
2020	C. Carballo Genetic estimates and immune response associated with the Lymphocystis Disease Virus (LCDV) in marine fish published pages: , ISSN: , DOI:		2020-02-28
2017	Joana Firmino, Carlos Carballo, Paula Armesto, Marco A. Campinho, Deborah M. Power, Manuel Manchado Phylogeny, expression patterns and regulation of DNA Methyltransferases in early development of the flatfish, Solea senegalensis published pages: , ISSN: 1471-213X, DOI: 10.1186/s12861-017-0154-0	BMC Developmental Biology 17/1	2020-01-29
2017	Anjos L, Cardoso JCR, Gardikis K, Power DM and Letsiou S In vitro effects of Cartilage acidic protein 1 on primary human dermal fibroblasts published pages: , ISSN: , DOI:	10th European Conferenceon Marine Natural Products proceedings	2020-01-29
2018	Konstantinos Gardikis, Sophia Letsiou Marine products as effective raw materials for cosmetics â€“ a research and innovation approach published pages: , ISSN: , DOI:	30th International Symposium on the Chemistry of Natural Products	2020-01-29
2018	Konstantinos Gardikis, Manuel Manchado, Israel Guerrero-CÃ³zar, Claudia Maya, Carlos Infante, Sophia Letsiou, Vasiliki-Ioanna Boka, William Helbert Chrysolaminarin encapsulation in cyclodextrins and hydrolyzed rice flour. In vitro and in vivo efficacy studies on human dermal fibroblasts and fish larvae published pages: , ISSN: , DOI:	BITâ€™s 8th Annual International Symposium of Drug Delivery Systems (SDDS-2018)	2020-01-29
2017	Carballo C.1, Chronopoulou E.2, Crespo A.1, Gardikis K.3, Labrou N.2, Manchado M.* CHARACTERIZATION OF HATCHING ENZYMES IN SOLE (S. SENEGALENSIS) BY USING GENOMIC APPROACHES TO BE USED AS A NEW BIOTECHNOLOGICAL PRODUCT published pages: , ISSN: , DOI:	International Flatfish Symposium 2017	2020-01-29
2018	Ana Manuela Crespo1, Carlos Carballo1, Lalia MantecÃ³n2y Manuel Manchado1 LA REPROGRAMACION EPIGENÃ‰TICA CON EXTRACTOS DE MICROALGAS MODIFICA LA TOLERANCIA A LA TEMPERATURA EN LARVAS DE LENGUADO published pages: , ISSN: , DOI:		2020-01-29
2017	Ioanna Anastasiou, Sophia Letsiou, Katerina I. Kalliampakou, Carlos Infante , William Helbert, Kostantinos Gardikis, Lalia MantecÃ³n and Emmanouil Flemetakis In vitro antioxidant and wound healing effects of cyanobacteria exopolysaccharides on primary human fibroblasts published pages: , ISSN: , DOI:	Proceedings of the 68th Helenic Biochemistry and Molecular Biology Society	2020-01-29
2018	PatrÃcia Pinto, C Carballo, AP Mateus, J Martinez-Blanch, F Codoner, L Mantecon, M Manchado, DM Power Microalgal polysaccharide extracts modulate the immune response and microbiome in the gut of Senegalese sole (Solea Senegalensis) published pages: , ISSN: , DOI:	31th New European Soc. for Comparative Physiology and Biochemistry (ESCPB 2018)	2020-01-29
2018	Carlos Carballo, Evangelia G. Chronopoulou, Sofia Letsiou, Claudia Maya, Nikolaos E. Labrou, Carlos Infante, Deborah M. Power, Manuel Manchado Antioxidant capacity and immunomodulatory effects of a chrysolaminarin-enriched extract in Senegalese sole published pages: 1-8, ISSN: 1050-4648, DOI: 10.1016/j.fsi.2018.07.052	Fish & Shellfish Immunology 82	2020-01-29
2017	Ioanna Anastasiou, Katerina I. Kalliampakou, Sophia Letsiou, Carlos Infante , William Helbert, Kostantinos Gardikis, Lalia Mantecon and Emmanouil Flemetakis. In vitro effects of cyanobacteria exopolysaccharides on primary human dermal cells published pages: , ISSN: , DOI:	10th European Conferenceon Marine Natural Products proceedings	2020-01-29
2018	FÃ©lix RC, Letsiou S, Anjos L, Gomes HL, Power DM Electric Cell-substrate Impedance Sensing (ECIS) as a method to test marine bioactive compounds in wound healing published pages: , ISSN: , DOI:	4th Conference on Impedance-Based Cell Assays (IBCA2018)	2020-01-29
2018	Patricia I.S. Pinto, ClÃ¡udia Guerreiro, Rita Costa, Juan F. Martinez-Blanch, Carlos Carballo, Francisco CodoÃ±er, Manuel Manchado, Deborah M Power Understanding pseudo-albinism in sole (Solea senegalensis): a transcriptomic and metagenomic approach published pages: , ISSN: 2045-2322, DOI:	Scientific Reports 11-2018	2020-01-29
2018	Carlos Carballo, Evangelia G. Chronopoulou; Sofia Letsiou; Claudia Maya; Nikolaos E. Labrou; Carlos Infante; Deborah M. Power; Manuel Manchado Estudio de las propiedades antioxidantes e inmunomoduladoras de la crisolaminarina published pages: , ISSN: , DOI:	IX Jornadas de Acuicultura en el Litoral SuratlÃ¡ntico - La Acuicultura Progresa	2020-01-29

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