Opendata, web and dolomites

EVOL-WNS

Genetic factors contributing to White Nose Syndrome tolerance in North American and European Myotis-bats

Total Cost €

0

EC-Contrib. €

0

Partnership

0

Views

0

 EVOL-WNS project word cloud

Explore the words cloud of the EVOL-WNS project. It provides you a very rough idea of what is the project "EVOL-WNS" about.

america    poolseq    caused    predict    syndrome    tolerance    causes    brandtii    orthologs    samples    conservation    prematurely    bats    2006    sweeps    million    destructans    reserves    training    epidermal    2007    myotis    originates    hibernation    profiles    once    infection    time    researcher    rates    populations    bottleneck    survivor    died    deposited    observe    understand    nose    mechanisms    pan    transferable    species    detection    tolerant    susceptible    pseudogymnoascus    white    consume    pathogens    arouse    genes    differ    genus    lucifugus    dna    fungal    fat    frequently    skills    validate    survivors    quartile    suitable    unknown    existed    genetic    tenured    position    infected    damage    last    onset    bat    sampled    psychrophilic    probably    fungus    gain    pd    co    disease    gene    transcriptomes    survival    winter    selective    population    appear    strategies    north    remnant    wildlife    archived    wns    candidate   

Project "EVOL-WNS" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY OF LIVERPOOL 

Organization address
address: BROWNLOW HILL 765 FOUNDATION BUILDING
city: LIVERPOOL
postcode: L69 7ZX
website: www.liverpool.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://www.liverpool.ac.uk
 Total cost 183˙454 €
 EC max contribution 183˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2015
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2016
 Duration (year-month-day) from 2016-11-01   to  2018-10-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY OF LIVERPOOL UK (LIVERPOOL) coordinator 183˙454.00

Map

 Project objective

White-Nose Syndrome (WNS) is a fungal disease affecting bats during hibernation. Since 2007, an estimated 6 million bats in North-America have died of the infection, which causes bats to prematurely consume the fat reserves deposited for winter hibernation. The infected bats arouse from hibernation more frequently; probably due to epidermal damage caused by Pseudogymnoascus destructans (Pd), a psychrophilic fungus. Pd originates from Europe, however, European bats appear to be tolerant to the infection. Tolerance has also been recently observed in remnant populations in the U.S, where these WNS-survivors have co-existed with the fungus since 2006. The mechanisms leading to adaptation or tolerance remain unknown. Here we aim to investigate genetic factors that may contribute to Pd-tolerance in the most frequently infected genus of bats, Myotis. By using DNA-samples from two Myotis species from North America (Myotis lucifugus) and Europe (Myotis brandtii), we should observe selection in gene orthologs between European bats and bats in WNS-survivor populations. The selection profiles should differ from archived WNS-susceptible bats, sampled before the onset of the wildlife disease. Once we have identified suitable candidate genes with PoolSeq and detection of selective sweeps, we will validate the results by comparing the transcriptomes of both infected WNS-susceptible and infected WNS-survivor M. lucifugus and infected M. brandtii in the last quartile of their hibernation. The results will demonstrate the pan-species and population-wide effects of a real-time bottleneck and help us understand the mechanisms promoting tolerance to the pathogens. The proposal will provide training in technical and transferable skills to allow the experienced researcher to gain a tenured position and achieve impact through conservation measures that help predict bat population survival rates and hibernation strategies.

 Publications

year authors and title journal last update
List of publications.
2018 Eero J. Vesterinen, Anna I. E. Puisto, Anna S. Blomberg, Thomas M. Lilley
Table for five, please: Dietary partitioning in boreal bats
published pages: 10914-10937, ISSN: 2045-7758, DOI: 10.1002/ece3.4559
Ecology and Evolution 8/22 2019-05-23
2019 Gonzalo Ossa, Joseph S. Johnson, Anna I. E. Puisto, Veikko Rinne, Ilari E. Sääksjärvi, Austin Waag, Eero J. Vesterinen, Thomas M. Lilley
The Klingon batbugs: Morphological adaptations in the primitive bat bugs, Bucimex chilensis and Primicimex cavernis , including updated phylogeny of Cimicidae
published pages: , ISSN: 2045-7758, DOI: 10.1002/ece3.4846
Ecology and Evolution 2019-05-23
2018 Thomas M. Lilley, Jani Anttila, Lasse Ruokolainen
Landscape structure and ecology influence the spread of a bat fungal disease
published pages: 2483-2496, ISSN: 0269-8463, DOI: 10.1111/1365-2435.13183
Functional Ecology 32/11 2019-05-23

Are you the coordinator (or a participant) of this project? Plaese send me more information about the "EVOL-WNS" project.

For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.

Send me an  email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.

Thanks. And then put a link of this page into your project's website.

The information about "EVOL-WNS" are provided by the European Opendata Portal: CORDIS opendata.

More projects from the same programme (H2020-EU.1.3.2.)

CoCoNat (2019)

Coordination in constrained and natural distributed systems

Read More  

TOPOCIRCUS (2019)

Simulations of Topological Phases in Superconducting Circuits

Read More  

MegaBiCycle (2019)

The role of megafauna in biogeochemical cycles and greenhouse gas fluxes: implications for climate and ecosystems throughout history

Read More