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UniPAT

Universal Pulses for Parallel Transmission and Magnetic Resonance Imaging

Total Cost €

EC-Contrib. €

Partnership

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UniPAT project word cloud

Explore the words cloud of the UniPAT project. It provides you a very rough idea of what is the project "UniPAT" about.

waveforms blindly special play transmitters maps solution transmission resonance erc counteract rf validity adult patient tool feasibility radiofrequency platform designed independently calculate calculation data appropriately inhomogeneity group generate market powerful acquired time performed respect technique proof patients remained 7t consists hence excitation brains parallel cohort healthy mri instigator thereby supporting minutes instrument variability experiments exam placing scientific first predesigned readily universal category plug corresponding human tools expertise calibration imaging implementable companies create subject pulses amplitude respective uniform coil volunteers ultra equipped clinical accumulating accessible magnetic algorithms database robustly sophisticated mostly commercial

Project "UniPAT" data sheet

The following table provides information about the project.

Coordinator	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 website: www.cea.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Total cost	149˙634 €
EC max contribution	149˙634 € (100%)
Programme	1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
Code Call	ERC-2015-PoC
Funding Scheme	ERC-POC
Starting year	2016
Duration (year-month-day)	from 2016-09-01 to 2018-02-28

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES Organization address address: RUE LEBLANC 25 city: PARIS 15 postcode: 75015 website: www.cea.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS 15)	coordinator	149˙634.00

Map

Project objective

The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject several RF transmitters that can be controlled independently in amplitude and phase. By using sophisticated algorithms, it is then possible to design the respective waveforms which lead to a uniform excitation. This powerful tool on the other hand has remained a research instrument mostly due to the calibration and calculation time necessary to exploit the technology in each exam (around 10 minutes), and the required expertise to calculate the waveforms. In this Proof-of-Concept project, we propose to establish the scientific validity, technical feasibility and market potential of universal RF pulses. The instigator of the project indeed has acquired supporting evidence during his ERC project that it is possible to generate a set of RF pulses predesigned to be robust with respect to patient variability. That way, the so-called “universal pulses” can be applied to a category of patients without any special calibration or particular expertise. The use of parallel transmission thereby could become accessible to any clinical MRI platform equipped appropriately. Universal pulses would represent a “plug and play” solution. This Proof-of-Concept project hence will be carried out by first accumulating the data necessary to create a database of RF field maps acquired on different human brains. Through the use of tools developed during the corresponding ERC project, the pulses will be designed to work robustly on the cohort. These pulses will then be blindly applied to a group of new healthy adult volunteers without any particular calibration or calculation. Experiments will be performed at 7T using a commercial RF coil to market the results better and offer a readily implementable product to companies.

Publications

List of publications.
year	authors and title	journal	last update
2017	Vincent Gras, Markus Boland, Alexandre Vignaud, Guillaume Ferrand, Alexis Amadon, Franck Mauconduit, Denis Le Bihan, Tony StÃ¶cker, Nicolas Boulant Homogeneous non-selective and slice-selective parallel-transmit excitations at 7 Tesla with universal pulses: A validation study on two commercial RF coils published pages: e0183562, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0183562	PLOS ONE 12/8	2019-06-13
2017	Vincent Gras, Franck Mauconduit, Alexandre Vignaud, Alexis Amadon, Denis Le Bihan, Tony StÃ¶cker, Nicolas Boulant Design of universal parallel-transmit refocusing k T -point pulses and application to 3D T 2 -weighted imaging at 7T published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27001	Magnetic Resonance in Medicine	2019-06-13

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