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UniPAT

Universal Pulses for Parallel Transmission and Magnetic Resonance Imaging

Total Cost €

0

EC-Contrib. €

0

Partnership

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 UniPAT project word cloud

Explore the words cloud of the UniPAT project. It provides you a very rough idea of what is the project "UniPAT" about.

solution    performed    scientific    patients    play    adult    clinical    human    universal    appropriately    healthy    parallel    create    subject    tool    experiments    feasibility    minutes    brains    commercial    maps    plug    accumulating    erc    7t    respect    mri    transmission    calculation    ultra    inhomogeneity    predesigned    transmitters    consists    first    counteract    robustly    special    implementable    cohort    proof    market    placing    rf    accessible    corresponding    thereby    validity    independently    respective    radiofrequency    equipped    uniform    platform    resonance    magnetic    excitation    imaging    blindly    algorithms    generate    coil    waveforms    remained    instigator    companies    category    acquired    hence    time    designed    expertise    amplitude    calibration    readily    sophisticated    exam    calculate    database    volunteers    variability    data    supporting    pulses    powerful    tools    technique    group    patient    instrument    mostly   

Project "UniPAT" data sheet

The following table provides information about the project.

Coordinator
COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES 

Organization address
address: RUE LEBLANC 25
city: PARIS 15
postcode: 75015
website: www.cea.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 149˙634 €
 EC max contribution 149˙634 € (100%)
 Programme 1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC))
 Code Call ERC-2015-PoC
 Funding Scheme ERC-POC
 Starting year 2016
 Duration (year-month-day) from 2016-09-01   to  2018-02-28

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES FR (PARIS 15) coordinator 149˙634.00

Map

 Project objective

The parallel transmission technology is a promising technique to counteract the radiofrequency (RF) field inhomogeneity problem in Magnetic Resonance Imaging (MRI) at ultra-high field. It consists of placing around the subject several RF transmitters that can be controlled independently in amplitude and phase. By using sophisticated algorithms, it is then possible to design the respective waveforms which lead to a uniform excitation. This powerful tool on the other hand has remained a research instrument mostly due to the calibration and calculation time necessary to exploit the technology in each exam (around 10 minutes), and the required expertise to calculate the waveforms. In this Proof-of-Concept project, we propose to establish the scientific validity, technical feasibility and market potential of universal RF pulses. The instigator of the project indeed has acquired supporting evidence during his ERC project that it is possible to generate a set of RF pulses predesigned to be robust with respect to patient variability. That way, the so-called “universal pulses” can be applied to a category of patients without any special calibration or particular expertise. The use of parallel transmission thereby could become accessible to any clinical MRI platform equipped appropriately. Universal pulses would represent a “plug and play” solution. This Proof-of-Concept project hence will be carried out by first accumulating the data necessary to create a database of RF field maps acquired on different human brains. Through the use of tools developed during the corresponding ERC project, the pulses will be designed to work robustly on the cohort. These pulses will then be blindly applied to a group of new healthy adult volunteers without any particular calibration or calculation. Experiments will be performed at 7T using a commercial RF coil to market the results better and offer a readily implementable product to companies.

 Publications

year authors and title journal last update
List of publications.
2017 Vincent Gras, Markus Boland, Alexandre Vignaud, Guillaume Ferrand, Alexis Amadon, Franck Mauconduit, Denis Le Bihan, Tony Stöcker, Nicolas Boulant
Homogeneous non-selective and slice-selective parallel-transmit excitations at 7 Tesla with universal pulses: A validation study on two commercial RF coils
published pages: e0183562, ISSN: 1932-6203, DOI: 10.1371/journal.pone.0183562
PLOS ONE 12/8 2019-06-13
2017 Vincent Gras, Franck Mauconduit, Alexandre Vignaud, Alexis Amadon, Denis Le Bihan, Tony Stöcker, Nicolas Boulant
Design of universal parallel-transmit refocusing k T -point pulses and application to 3D T 2 -weighted imaging at 7T
published pages: , ISSN: 0740-3194, DOI: 10.1002/mrm.27001
Magnetic Resonance in Medicine 2019-06-13

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