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TRACT SIGNED

Training in Cancer Mechanisms and Therapeutics

Total Cost €

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EC-Contrib. €

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Partnership

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Outcomes and
results

TRACT project word cloud

Explore the words cloud of the TRACT project. It provides you a very rough idea of what is the project "TRACT" about.

generate employment diagnostics specialised complementary training section biochemists imaging survival position exosome interdisciplinary receive detection identification cellular therapies cancers patients entire oral trained drug expertise chemists molecular stage economy diagnosis public genome tract private insights countries cohort last metabolomics career global immunologists computational metabolism 75 cross resistance validation options sequencing engagement entrepreneurship basis biomarker commercialisation tools therapeutics esrs internationally medicinal skills medicine courses chemistry isolation oesophageal drive metabolite treatment cancer brings translational mobile community patient collaborative placements discover diagnostic resolution technologies screening industrial clinicians presentation diagnosed rates disease crispr enhanced generation prospects 50

Project "TRACT" data sheet

The following table provides information about the project.

Coordinator	THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Organization address address: College Green city: DUBLIN postcode: 2 website: www.tcd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Ireland [IE]
Project website	http://www.qub.ac.uk/sites/TraininginCancerMechanismsandTherapeutics/
Total cost	2˙877˙076 €
EC max contribution	2˙877˙076 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2016
Funding Scheme	MSCA-ITN-ETN
Starting year	2016
Duration (year-month-day)	from 2016-10-01 to 2020-09-30

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN Organization address address: College Green city: DUBLIN postcode: 2 website: www.tcd.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	coordinator	1˙062˙698.00
2	THE QUEEN'S UNIVERSITY OF BELFAST THE QUEEN'S UNIVERSITY OF BELFAST Organization address address: UNIVERSITY ROAD LANYON BUILDING city: BELFAST postcode: BT7 1NN website: www.qub.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BELFAST)	participant	546˙575.00
3	UNIVERSITA DEGLI STUDI DI SIENA UNIVERSITA DEGLI STUDI DI SIENA Organization address address: VIA BANCHI DI SOTTO 55 city: SIENA postcode: 53100 website: www.unisi.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (SIENA)	participant	516˙122.00
4	UNIVERSITAT DE VALENCIA UNIVERSITAT DE VALENCIA Organization address address: AVENIDA BLASCO IBANEZ 13 city: VALENCIA postcode: 46010 website: www.uv.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (VALENCIA)	participant	495˙745.00
5	OROBOROS INSTRUMENTS GmbH OROBOROS INSTRUMENTS GmbH Organization address address: SCHOPFSTRASSE 18 city: INNSBRUCK postcode: 6020 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (INNSBRUCK)	participant	255˙934.00
6	ALMAC DIAGNOSTIC SERVICES LIMITED ALMAC DIAGNOSTIC SERVICES LIMITED Organization address address: SEAGOE INDUSTRIAL ESTATE 20 city: CRAIGAVON postcode: BT63 5QD website: www.almacgroup.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (CRAIGAVON)	partner	0.00
7	ANDOR TECHNOLOGY LIMITED ANDOR TECHNOLOGY LIMITED Organization address address: MILLENNIUM WAY 7 SPRINGVALE BUSINESS PARK city: BELFAST postcode: BT12 7AL website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (BELFAST)	partner	0.00
8	Exosomics Siena S.p.A. Exosomics Siena S.p.A. Organization address address: n.a. city: Siena postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (Siena)	partner	0.00
9	Fraunhofer Society Fraunhofer Society Organization address address: n.a. city: Munich postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (Munich)	partner	0.00
10	NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED NATIONAL INSTITUTE FOR BIOPROCESSING RESEARCH AND TRAINING LIMITED Organization address address: FOSTERS AVENUE MOUNT MERRION city: BLACKROCK DUBLIN postcode: 4 website: www.nibrt.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (BLACKROCK DUBLIN)	partner	0.00
11	Opsona Therapeutics Opsona Therapeutics Organization address address: TARA STREET ASHFORD HOUSE 2ND FLOOR city: DUBLIN postcode: 2 website: www.opsona.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (DUBLIN)	partner	0.00
12	Seahorse Seahorse Organization address address: n.a. city: London postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (London)	partner	0.00

Map

Project objective

The European community requires early stage researchers (ESRs) trained in next-generation technologies for improved detection and treatment of oral and oesophageal cancers. The number of oral cancers diagnosed in the EU has increased by over 75% in the last 30 years, with long-term survival rates of only 50%. This is typically due to the late diagnosis of the disease and resistance to current therapies. Through the collaborative expertise of clinicians, biochemists, immunologists, and chemists TRACT will enable ESRs to discover novel insights into the molecular and cellular basis of these cancers and generate new diagnostic tools and therapeutics that improve patient response and survival. Each Institution brings unique but complementary expertise in cancer metabolism, metabolomics, high-resolution imaging, biomarker identification, computational modelling, medicinal chemistry, target validation, drug development and translational medicine. Industrial placements in five European countries will ensure ESRs receive specialised training in the development of next-generation technologies in such areas as whole genome sequencing, CRISPR technology, drug screening, exosome isolation and analysis, cancer imaging, metabolism and metabolite analysis in addition to the unique employment experience of working in the private sector. Courses in commercialisation, project management and presentation skills will ensure ESRs will have the ability to present their results to the entire cross-section of the European community, through public engagement. TRACT will deliver a cohort of internationally mobile cancer researchers with interdisciplinary skills who will have enhanced career prospects and be in a position to have an impact on the European and global research stage by providing new technologies that can drive entrepreneurship into the European economy and improved diagnostics and treatment options for cancer patients in Europe and beyond.

Deliverables

List of deliverables.
Recruitment strategy	Documents, reports	2019-07-09 10:17:50
Dissemination diary, Year 1	Documents, reports	2019-07-09 10:17:50
ESR traning and progress year 1	Documents, reports	2019-07-09 10:17:50

Take a look to the deliverables list in detail: detailed list of TRACT deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	VR Dikova, S Principe, JV Bagan Salivary inflammatory proteins in patients with oral potentially malignant disorders published pages: 0-0, ISSN: 1989-5488, DOI: 10.4317/jced.55917	Journal of Clinical and Experimental Dentistry	2020-01-30
2019	S Principe, V Dikova, J Bagan Salivary Cytokines in patients with Head and Neck Cancer (HNC) treated with Radiotherapy published pages: 0-0, ISSN: 1989-5488, DOI: 10.4317/jced.56318	Journal of Clinical and Experimental Dentistry	2020-01-30
2018	Stefano Federico, Tuhina Khan, Nicola Relitti, Giulia Chemi, Margherita Brindisi, Simone Brogi, Ettore Novellino, Daniela M. Zisterer, Giuseppe Campiani, Sandra Gemma, Stefania Butini A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents published pages: 4466-4470, ISSN: 0040-4039, DOI: 10.1016/j.tetlet.2018.11.005	Tetrahedron Letters 59/51	2019-07-09
2018	Brian Flood, Joan Manils, Ciara Nulty, Ewelina Flis, Sinead Kenealy, Gillian Barber, Joanna Fay, Kingston H. G. Mills, Elaine W. Kay, Emma M. Creagh Caspase-11 regulates the tumour suppressor function of STAT1 in a murine model of colitis-associated carcinogenesis published pages: , ISSN: 0950-9232, DOI: 10.1038/s41388-018-0613-5	Oncogene	2019-07-09
2018	Jaine K. Blayney, Lauren Cairns, Gerald Li, Niamh McCabe, Leanne Stevenson, Christopher J. Peters, Nathan B. Reid, Veronica J. Spence, Chintapuza Chisambo, Damian McManus, Jacqueline James, Stephen McQuaid, Stephanie Craig, Kenneth Arthur, Darragh McArt, Chin-Ann J. Ong, Pierre Lao-Sirieix, Peter Hamilton, Manuel Salto-Tellez, Martin Eatock, Helen G. Coleman, Rebecca C. Fitzgerald, Richard D. Kennedy, Richard C. Turkington Glucose transporter 1 expression as a marker of prognosis in oesophageal adenocarcinoma published pages: , ISSN: 1949-2553, DOI: 10.18632/oncotarget.24906	Oncotarget 9/26	2019-07-09
2019	Margherita Brindisi, Cristina Ulivieri, Gloria Alfano, Sandra Gemma, Francisco de AsÃs Balaguer, Tuhina Khan, Alessandro Grillo, Giulia Chemi, GrÃ©gory Menchon, Andrea E. Prota, Natacha Olieric, Daniel Lucena-Agell, Isabel Barasoain, J. Fernando Diaz, Angela Nebbioso, Mariarosaria Conte, Ludovica Lopresti, Stefania Magnano, Rebecca Amet, Paula Kinsella, Daniela M. Zisterer, Ola Ibrahim, Jeff O\'Sullivan, Lucia Morbidelli, Roberta Spaccapelo, Cosima Baldari, Stefania Butini, Ettore Novellino, Giuseppe Campiani, Lucia Altucci, Michel O. Steinmetz, Simone Brogi Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents published pages: 290-320, ISSN: 0223-5234, DOI: 10.1016/j.ejmech.2018.11.004	European Journal of Medicinal Chemistry 162	2019-07-09

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The information about "TRACT" are provided by the European Opendata Portal: CORDIS opendata.

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