RNAging SIGNED
The role of non coding RNA in organismal ageing
Total Cost €
0EC-Contrib. €
0Partnership
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0RNAging project word cloud
Explore the words cloud of the RNAging project. It provides you a very rough idea of what is the project "RNAging" about.
Project "RNAging" data sheet
The following table provides information about the project.
| Coordinator |
IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE
Organization address contact info |
| Coordinator Country | Italy [IT] |
| Total cost | 149˙950 € |
| EC max contribution | 149˙950 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2016-PoC |
| Funding Scheme | ERC-POC |
| Starting year | 2017 |
| Duration (year-month-day) | from 2017-03-01 to 2018-08-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | IFOM FONDAZIONE ISTITUTO FIRC DI ONCOLOGIA MOLECOLARE | IT (MILANO) | coordinator | 149˙950.00 |
Map
Project objective
The DNA damage response (DDR) is a set of cellular events that follow the generation of a DNA damage. We have previously discovered a novel class of small non-coding RNAs, named DNA damage RNAs (DDRNAs), which are necessary for the full DDR activation upon a DNA double-strand break generation. Our preliminary data show that also at damaged/dysfunctional telomeres telomeric transcrips are produced. By using antisense oligonucleotides (ASOs) targeting them, we aim at modulating DDR in cultured cells and in vivo in animal models.
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