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Opendata, web and dolomites

META-CAN SIGNED

Targeting the metabolism-immune system connections in Cancer

Total Cost €

EC-Contrib. €

Partnership

Views

Outcomes and
results

META-CAN project word cloud

Explore the words cloud of the META-CAN project. It provides you a very rough idea of what is the project "META-CAN" about.

network profound pan navigate cancer sectors tissue immune cell layers cells scientific warburg provides hampered clinicians escape point training regulate exploited explore prognostic oncogenes markers coherent commercial industry regulation members corporate therapeutic glucose academic world communication scientists metabolism convert stroma multidisciplinary ease effect interplay body interdisciplinary hypothesis skills levels limited tumor specialists clinical death pharma conduct nutrients origin excellence diagnostic outreach shortage discovering intersectoral intervention independently collaborations complementary academics susceptibility young complexity hypoxia modulation metabolic industrial exerts drugs adaptations context therapies anti describing regulators

Project "META-CAN" data sheet

The following table provides information about the project.

Coordinator	FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE Organization address address: AVENIDA GRAN VIA HOSPITALET 199-203 city: L'HOSPITALET DE LLOBREGAT postcode: 8908 website: www.idibell.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	https://www.metacan.eu/
Total cost	3˙831˙957 €
EC max contribution	3˙831˙957 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2017
Funding Scheme	MSCA-ITN-ETN
Starting year	2017
Duration (year-month-day)	from 2017-09-01 to 2021-08-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE Organization address address: AVENIDA GRAN VIA HOSPITALET 199-203 city: L'HOSPITALET DE LLOBREGAT postcode: 8908 website: www.idibell.cat contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (L'HOSPITALET DE LLOBREGAT)	coordinator	743˙618.00
2	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	525˙751.00
3	MEDIZINISCHE UNIVERSITAET WIEN MEDIZINISCHE UNIVERSITAET WIEN Organization address address: SPITALGASSE 23 city: WIEN postcode: 1090 website: www.meduniwien.ac.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	participant	511˙868.00
4	VIB VZW VIB VZW Organization address address: RIJVISSCHESTRAAT 120 city: ZWIJNAARDE - GENT postcode: 9052 website: www.vib.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (ZWIJNAARDE - GENT)	participant	501˙120.00
5	TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD Organization address address: THE SENATE BUILDING TECHNION CITY 1 city: HAIFA postcode: 32000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (HAIFA)	participant	455˙525.00
6	EVOTEC (FRANCE) SAS EVOTEC (FRANCE) SAS Organization address address: 195 ROUTE D'ESPAGNE city: TOULOUSE CEDEX postcode: 31036 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (TOULOUSE CEDEX)	participant	262˙875.00
7	UNIVERSITE PARIS DESCARTES UNIVERSITE PARIS DESCARTES Organization address address: RUE DE L ECOLE DE MEDECINE 12 city: PARIS CEDEX 06 postcode: 75270 website: www.univ-paris5.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS CEDEX 06)	participant	262˙875.00
8	AMC MEDICAL RESEARCH BV AMC MEDICAL RESEARCH BV Organization address address: MEIBERGDREEF 9 city: AMSTERDAM ZUIDOOST postcode: 1105AZ website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM ZUIDOOST)	participant	255˙374.00
9	APPLIED RESEARCH USING OMIC SCIENCES SL APPLIED RESEARCH USING OMIC SCIENCES SL Organization address address: CALLE VICTOR PRADERA 45 city: CORNELLA postcode: 8940 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (CORNELLA)	participant	247˙872.00
10	IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD IBM ISRAEL - SCIENCE AND TECHNOLOGY LTD Organization address address: 94 DERECH EM-HAMOSHAVOT city: PETACH TIKVA postcode: 49527 website: www.haifa.il.ibm.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (PETACH TIKVA)	participant	65˙075.00
11	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	0.00
12	ASSISTANCE PUBLIQUE HOPITAUX DE PARIS ASSISTANCE PUBLIQUE HOPITAUX DE PARIS Organization address address: 3 AVENUE VICTORIA city: PARIS postcode: 75000 website: http://www.aphp.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	0.00
13	TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY Organization address address: SENATE BUILDING TECHNION CITY city: HAIFA postcode: 32000 website: www.technion.ac.il contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IL (HAIFA)	participant	0.00
14	BIOcomuniCAT BIOcomuniCAT Organization address address: n.a. city: Barcelona postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (Barcelona)	partner	0.00
15	BOEHRINGER INGELHEIM RCV GMBH & CO KG BOEHRINGER INGELHEIM RCV GMBH & CO KG Organization address address: DR BOEHRINGER GASSE 5-11 city: WIEN postcode: 1121 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (WIEN)	partner	0.00
16	Canceropole PACA Canceropole PACA Organization address address: n.a. city: Marseille postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (Marseille)	partner	0.00
17	FUNDACION ESADE FUNDACION ESADE Organization address address: AVENIDA PEDRALBES 60-62 city: BARCELONA postcode: 8034 website: www.esade.edu contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (BARCELONA)	partner	0.00
18	HOSPITAL SANT JOAN DE DÉU HOSPITAL SANT JOAN DE DÉU Organization address address: PASEO SANT JOAN DE DEU 2 city: ESPLUGUES DE LLOBREGAT postcode: 8950 website: www.hsjdbcn.org contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (ESPLUGUES DE LLOBREGAT)	partner	0.00
19	Seahorse Bio (Agilent Technologies) Seahorse Bio (Agilent Technologies) Organization address address: n.a. city: North Billerica postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	US (North Billerica)	partner	0.00
20	The FEBS Journal (FEBS) The FEBS Journal (FEBS) Organization address address: n.a. city: Cambridge postcode: n.a. website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (Cambridge)	partner	0.00

Map

Project objective

'Cancer cells show common features of profound metabolic changes and escape from the immune system, independently of their tissue of origin. These metabolic adaptations are not limited to glucose metabolism (the 'Warburg effect') but are more general and affect several metabolic pathways in cancer cells as well as in the stroma, including immune cells. This network will explore how nutrients and hypoxia regulate the tumor-immune system interplay, and how this communication is controlled by oncogenes, metabolic regulators and current or potential drugs targeting metabolism. Understanding how metabolism can affect tumor cells and the anti-cancer immune response represents a potential therapeutic intervention point that can be exploited to develop novel therapies and new diagnostic and prognostic markers. The development of therapies targeting cancer metabolism is hampered by: 1) the complexity of the regulation that metabolism exerts on many different tumor layers, which requires multidisciplinary collaborations, and 2) the shortage of scientists that can navigate with ease between academic, industrial and clinical sectors and have the scientific and complementary skills to convert research findings into commercial and clinical applications. This network provides a pan-European interdisciplinary and intersectoral training program of excellence bringing young researchers together with World leading academics, clinicians, pharma industry members, corporate research and dissemination and outreach specialists. As part of the research training, the consortium will conduct a coherent and integrated set of hypothesis-driven research projects that are aimed at discovering, describing and exploiting how metabolism at the cell and the whole body levels is integrated with modulation of cell death susceptibility and the immune response in the context of cancer. '

Deliverables

List of deliverables.
First Scientific Training	Other	2020-01-14 14:33:10
Second Scientific Training	Other	2020-01-14 14:33:07
Website	Websites, patent fillings, videos etc.	2020-01-14 14:33:11
Second complementary skills training	Other	2020-01-14 14:33:14
First Complementary skills training	Other	2020-01-14 14:33:10
ESR recruitment start	Other	2020-01-14 14:33:13
Social Media accounts	Websites, patent fillings, videos etc.	2020-01-14 14:33:08

Take a look to the deliverables list in detail: detailed list of META-CAN deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	PaweÅ‚ Bieniasz-Krzywiec, Rosa MartÃn-PÃ©rez, Manuel Ehling, Melissa GarcÃa-Caballero, Sotiria Pinioti, Samantha Pretto, Roel Kroes, Chiara Aldeni, Mario Di Matteo, Hans Prenen, MarÃa Virginia Tribulatti, Oscar Campetella, Ann Smeets, Agnes Noel, Giuseppe Floris, Jo A. Van Ginderachter, Massimiliano Mazzone Podoplanin-Expressing Macrophages Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer published pages: , ISSN: 1550-4131, DOI: 10.1016/j.cmet.2019.07.015	Cell Metabolism	2019-10-08
2019	Adam Spiro, Jonatan FernÃ¡ndez GarcÃa, Chen Yanover Inferring new relations between medical entities using literature curated term co-occurrences published pages: , ISSN: 2574-2531, DOI: 10.1093/jamiaopen/ooz022	JAMIA Open	2019-09-02
2019	Johanna Chiche, Julie Reverso-Meinietti, Annabelle Mouchotte, Camila Rubio-PatiÃ±o, Rana Mhaidly, Elodie Villa, Jozef P. Bossowski, Emma Proics, Manuel Grima-Reyes, AgnÃ¨s Paquet, Konstantina Fragaki, Sandrine Marchetti, Josette Briere, Damien Ambrosetti, Jean-FranÃ§ois Michiels, Thierry Jo Molina, Christiane Copie-Bergman, Jacqueline Lehmann-Che, Isabelle Peyrottes, Frederic Peyrade, Eric de Kerviler, Bruno Taillan, Georges Garnier, Els Verhoeyen, VÃ©ronique Paquis-Flucklinger, Laetitia Shintu, Vincent Delwail, Celine Delpech-Debiais, Richard Delarue, AndrÃ© Bosly, Tony Petrella, Gabriel Brisou, Bertrand Nadel, Pascal Barbry, Nicolas Mounier, Catherine Thieblemont, Jean-Ehrland Ricci GAPDH Expression Predicts the Response to R-CHOP, the Tumor Metabolic Status, and the Response of DLBCL Patients to Metabolic Inhibitors published pages: , ISSN: 1550-4131, DOI: 10.1016/j.cmet.2019.02.002	Cell Metabolism	2019-07-08

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