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EvoCELL SIGNED

Animal evolution from a cell type perspective: multidisciplinary training in single-cell genomics, evo-devo and in science outreach

Total Cost €

EC-Contrib. €

Partnership

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EvoCELL project word cloud

Explore the words cloud of the EvoCELL project. It provides you a very rough idea of what is the project "EvoCELL" about.

focussing lineages waters diverse pioneer expertise distinguished bodies recapitulated first fundamental stunning breadth skilled evolution groups excellence arise models uncoordinated scientists multicellular synergy efforts tools lay stem fertilised roles genes single divides questions ancestors foundation employ countless one life underexplored biodiversity compose differentiate expand differentiation types undifferentiated lab generation adult sequencing starting multidisciplinary outside evolutionary cells diversity egg progeny emergence represented animals world harness posses home vast phyla branch devo time exploring events expresses evocell branches body richly data training cell animal jointly evo genomics cycles neural

Project "EvoCELL" data sheet

The following table provides information about the project.

Coordinator	EUROPEAN MOLECULAR BIOLOGY LABORATORY Organization address address: Meyerhofstrasse 1 city: HEIDELBERG postcode: 69117 website: http://www.embl.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Germany [DE]
Total cost	3˙794˙519 €
EC max contribution	3˙794˙519 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2017
Funding Scheme	MSCA-ITN-ETN
Starting year	2018
Duration (year-month-day)	from 2018-01-01 to 2021-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	EUROPEAN MOLECULAR BIOLOGY LABORATORY EUROPEAN MOLECULAR BIOLOGY LABORATORY Organization address address: Meyerhofstrasse 1 city: HEIDELBERG postcode: 69117 website: http://www.embl.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HEIDELBERG)	coordinator	581˙505.00
2	CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS Organization address address: RUE MICHEL ANGE 3 city: PARIS postcode: 75794 website: www.cnrs.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	participant	679˙095.00
3	THE UNIVERSITY OF EXETER THE UNIVERSITY OF EXETER Organization address address: THE QUEEN'S DRIVE NORTHCOTE HOUSE city: EXETER postcode: EX4 4QJ website: www.ex.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (EXETER)	participant	364˙383.00
4	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	364˙383.00
5	UNIVERSITETET I BERGEN UNIVERSITETET I BERGEN Organization address address: MUSEPLASSEN 1 city: BERGEN postcode: 5020 website: www.uib.no contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NO (BERGEN)	participant	357˙844.00
6	STAZIONE ZOOLOGICA ANTON DOHRN STAZIONE ZOOLOGICA ANTON DOHRN Organization address address: Villa Comunale city: NAPOLI postcode: 80121 website: www.szn.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (NAPOLI)	participant	344˙081.00
7	MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN MUSEUM FUR NATURKUNDE - LEIBNIZ-INSTITUT FUR EVOLUTIONS- UND BIODIVERSITATSFORSCHUNG AN DER HUMBOLDT-UNIVERSITAT ZU BERLIN Organization address address: INVALIDENSTRASSE 43 city: BERLIN postcode: 10115 website: www.naturkundemuseum-berlin.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	332˙288.00
8	UPPSALA UNIVERSITET UPPSALA UNIVERSITET Organization address address: VON KRAEMERS ALLE 4 city: UPPSALA postcode: 751 05 website: www.uu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (UPPSALA)	participant	263˙659.00
9	GENOMIX4LIFE SRL GENOMIX4LIFE SRL Organization address address: VIA S. ALLENDE 1 city: BARONISSI postcode: 84081 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (BARONISSI)	participant	258˙061.00
10	RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG RUPRECHT-KARLS-UNIVERSITAET HEIDELBERG Organization address address: SEMINARSTRASSE 2 city: HEIDELBERG postcode: 69117 website: www.uni-heidelberg.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HEIDELBERG)	participant	249˙216.00

Map

Project objective

One of the first events in the evolution of multicellular animals was the differentiation of cells into distinct types with different roles. Starting from their most simple multicellular ancestors, the cells that compose animal bodies have become increasingly diverse; each cell type distinguished by the unique set of genes it expresses. This increase in diversity of cell types over evolutionary time is recapitulated in the process of development during which a single undifferentiated cell - the fertilised egg - divides and its progeny differentiate into the countless cell types of the adult body. Currently we do not even know how many distinct cell types animals posses, how new cell types arise in evolution, how many are in common between different animal groups and how many unique cell types have evolved in different lineages. Our aim in EvoCELL is to lay the foundation for a new branch of evo-devo focussing on cell types. We will study these fundamental questions in animal evolution and development using a new technology - single cell sequencing - which we will for the first time employ outside of lab models to sample the great diversity of animal phyla. Europe is home to world-leading expertise in evo-devo and single-cell genomics, but research and training efforts are as yet uncoordinated and their potential for synergy underexplored. EvoCELL will harness and expand this European excellence by training a new generation of multidisciplinary scientists skilled in exploring the vast breadth of animal differentiation. We will jointly sample data from all major animal lineages, richly represented in the biodiversity of European waters, and develop new tools for comparative analyses, through which we will together pioneer three branches of cell evo-devo: evolution of stem cells; emergence of animal life cycles, and the stunning diversity of neural cell types.

Deliverables

List of deliverables.
Website	Websites, patent fillings, videos etc.	2020-04-16 14:24:34
Practical Course II	Other	2020-04-16 14:24:30
Practical Course I	Other	2020-04-16 14:24:25

Take a look to the deliverables list in detail: detailed list of EvoCELL deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2018	Margherita Perillo, Periklis Paganos, Teresa Mattiello, Maria Cocurullo, Paola Oliveri, Maria I. Arnone New Neuronal Subtypes With a â€œPre-Pancreaticâ€ Signature in the Sea Urchin Stongylocentrotus purpuratus published pages: 1-12, ISSN: 1664-2392, DOI: 10.3389/fendo.2018.00650	Frontiers in Endocrinology 9	2020-01-30
2019	Assunta Sellitto, Konstantinos Geles, Ylenia Dâ€™Agostino, Marisa Conte, Elena Alexandrova, Domenico Rocco, Giovanni Nassa, Giorgio Giurato, Roberta Tarallo, Alessandro Weisz, Francesca Rizzo Molecular and Functional Characterization of the Somatic PIWIL1/piRNA Pathway in Colorectal Cancer Cells published pages: 1390, ISSN: 2073-4409, DOI: 10.3390/cells8111390	Cells 8/11	2020-01-30
2019	Milena MarinkoviÄ‡, JÃ¼rgen Berger, GÃ¡spÃ¡r JÃ©kely Neuronal coordination of motile cilia in locomotion and feeding published pages: , ISSN: 0962-8436, DOI:	Phil. Trans. R. Soc. B	2019-12-17

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The information about "EVOCELL" are provided by the European Opendata Portal: CORDIS opendata.