DeLIVER SIGNED
Super-resolution optical microscopy of nanosized pore dynamics in endothelial cells
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0DeLIVER project word cloud
Explore the words cloud of the DeLIVER project. It provides you a very rough idea of what is the project "DeLIVER" about.
Project "DeLIVER" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITAET BIELEFELD
Organization address contact info |
| Coordinator Country | Germany [DE] |
| Total cost | 3˙728˙513 € |
| EC max contribution | 3˙728˙513 € (100%) |
| Programme |
1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers) |
| Code Call | H2020-MSCA-ITN-2017 |
| Funding Scheme | MSCA-ITN-ETN |
| Starting year | 2018 |
| Duration (year-month-day) | from 2018-01-01 to 2021-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITAET BIELEFELD | DE (BIELEFELD) | coordinator | 747˙649.00 |
| 2 | UNIVERSITETET I TROMSOE - NORGES ARKTISKE UNIVERSITET | NO (TROMSO) | participant | 1˙145˙100.00 |
| 3 | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD | UK (OXFORD) | participant | 273˙287.00 |
| 4 | THE UNIVERSITY OF BIRMINGHAM | UK (BIRMINGHAM) | participant | 273˙287.00 |
| 5 | GOETEBORGS UNIVERSITET | SE (GOETEBORG) | participant | 263˙659.00 |
| 6 | CHERRY BIOTECH | FR (RENNES) | participant | 262˙875.00 |
| 7 | ELVESYS | FR (PARIS) | participant | 262˙875.00 |
| 8 | VRIJE UNIVERSITEIT BRUSSEL | BE (BRUSSEL) | participant | 250˙560.00 |
| 9 | LAVISION BIOTEC GMBH | DE (BIELEFELD) | participant | 249˙216.00 |
| 10 | ANZAC Health & Medical Research Foundation | AU (CONCORD NSW) | partner | 0.00 |
| 11 | BAYER AKTIENGESELLSCHAFT | DE (Leverkusen) | partner | 0.00 |
| 12 | Norinnova Technology Transfer AS | NO (Tromsø) | partner | 0.00 |
| 13 | THE UNIVERSITY OF HONG KONG | HK (Pokfulam) | partner | 0.00 |
| 14 | United States Department of Health and Human Services | US (Washington D.C.) | partner | 0.00 |
Map
Project objective
DeLIVER will train a new generation of ESRs in the development and application of newly developed high speed and high resolution imaging tools in biomedical research. ESRs will be cross-pollinated with concepts and skills in physics and biomedicine, in particular in super-resolution optical imaging (a.k.a. optical nanoscopy), analytical image reconstruction, and optical micro-manipulation methods. These skills are applied to reveal for the first time the function and dynamics of nanosized pores in endothelial cells (EC) that present the main barrier between the blood and vital organs for human physiology, such as the liver, brain, kidneys, and the eyes. Very little is known about the extremely important physiological function of these unique structures and their role in the transfer and/or clearance of metabolites and pharmaceuticals to vital organs. The current generation of optical nanoscopes, however, is rather slow and can only be applied to isolated, typically fixed (i.e. dead) cells rather than biomedically relevant tissues. Also, newcomers to the field need to familiarize themselves with a whole new set of potential problems that might arise in the use of optical nanoscopy, such as image reconstruction-related artifacts to name just one example.This is an area of research where European enterprises are very active. Excellent training in new scientific and complementary skills, combined with international and intersectoral work experience, will instil an innovative, creative and entrepreneurial mind-set in DeLIVER's ESRs, maximising economic benefits based on scientific discoveries. These specialised, highly trained, and mobile ESRs will have greatly enhanced career prospects. The training in novel physical methods with highly relevant experience in the biomedical sciences will allow them to confidently navigate at the interface of academic, clinical and private sector research.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Adrien Descloux, Marcel Müller, Vytautas Navikas, Andreas Markwirth, Robin van den Eynde, Tomas Lukes, Wolfgang Hübner, Theo Lasser, Aleksandra Radenovic, Peter Dedecker, Thomas Huser High-speed multiplane structured illumination microscopy of living cells using an image-splitting prism published pages: 143-148, ISSN: 2192-8614, DOI: 10.1515/nanoph-2019-0346 |
Nanophotonics 9/1 | 2020-03-05 |
| 2019 |
Robin Van den Eynde, Alice Sandmeyer, Wim Vandenberg, Sam Duwé, Wolfgang Hübner, Thomas Huser, Peter Dedecker, Marcel Müller Quantitative comparison of camera technologies for cost-effective super-resolution optical fluctuation imaging (SOFI) published pages: 44001, ISSN: 2515-7647, DOI: 10.1088/2515-7647/ab36ae |
Journal of Physics: Photonics 1/4 | 2020-03-05 |
| 2019 |
Andreas Markwirth, Mario Lachetta, Viola Mönkemöller, Rainer Heintzmann, Wolfgang Hübner, Thomas Huser, Marcel Müller Video-rate multi-color structured illumination microscopy with simultaneous real-time reconstruction published pages: , ISSN: 2041-1723, DOI: 10.1038/s41467-019-12165-x |
Nature Communications 10/1 | 2020-03-05 |
| 2020 |
Cihang Kong, Christian Pilger, Henning Hachmeister, Xiaoming Wei, Tom H. Cheung, Cora S. W. Lai, Nikki P. Lee, Kevin. K. Tsia, Kenneth K. Y. Wong, Thomas Huser High-contrast, fast chemical imaging by coherent Raman scattering using a self-synchronized two-colour fibre laser published pages: , ISSN: 2047-7538, DOI: 10.1038/s41377-020-0259-2 |
Light: Science & Applications 9/1 | 2020-03-05 |
| 2020 |
NIKHIL JAYAKUMAR, Azeem Ahmad, Dalip Mehta, Balpreet Ahluwalia Sampling moiré method: a tool for sensing quadratic phase distortion and its correction for accurate quantitative phase microscopy published pages: , ISSN: 1094-4087, DOI: 10.1364/oe.383461 |
Optics Express | 2020-03-05 |
| 2018 |
Cristina I. Øie, Viola Mönkemöller, Wolfgang Hübner, Mark Schüttpelz, Hong Mao, Balpreet S. Ahluwalia, Thomas R. Huser, Peter McCourt New ways of looking at very small holes – using optical nanoscopy to visualize liver sinusoidal endothelial cell fenestrations published pages: 575-596, ISSN: 2192-8614, DOI: 10.1515/nanoph-2017-0055 |
Nanophotonics 7/3 | 2020-02-21 |
| 2018 |
Viola Mönkemöller, Hong Mao, Wolfgang Hübner, Gianina Dumitriu, Peter Heimann, Gahl Levy, Thomas Huser, Barbara Kaltschmidt, Christian Kaltschmidt, Cristina I. Øie Primary rat LSECs preserve their characteristic phenotype after cryopreservation published pages: 10, ISSN: 2045-2322, DOI: 10.1038/s41598-018-32103-z |
Scientific Reports 8/1 | 2020-02-21 |
| 2019 |
Lothar Schermelleh, Alexia Ferrand, Thomas Huser, Christian Eggeling, Markus Sauer, Oliver Biehlmaier, Gregor P. C. Drummen Super-resolution microscopy demystified published pages: 72-84, ISSN: 1465-7392, DOI: 10.1038/s41556-018-0251-8 |
Nature Cell Biology 21/1 | 2020-02-21 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "DELIVER" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "DELIVER" are provided by the European Opendata Portal: CORDIS opendata.