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STriTuVaD project deliverables

The page lists 9 deliverables related to the research project "STriTuVaD".

 List of Deliverables

STriTuVaD: list of downloadable deliverables.
title and desprition type last update

Report on the extensions implemented into the modeling simulation platform to reproduce the immune system – TBC – vaccines interactions and dynamics

The goal of this deliverable is to integrate into UISS modeling framework the capability to simulate the dynamics and the specific features of the tuberculosis mycobacterium infection. Moreover the UISS modeling framework will be enabled to simulate the artificial immunity induced by two vaccines i.e., Ruti vaccine and ID93 vaccine.

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

Report on the creation of the subjects-specific and virtual patients libraries that will be used in the implementation of the in silico clinical trial

The purpose of this deliverable is to create a set of subjects-specific models with the aim to reproduce biological diversity of the subjects. Hence, the library of subjects created will be personalized with a “vector of features” that identifies a specific real patient with the final goal to to obtain a library of virtual M. tuberculosis infected patients that will be vaccinated and treated accordingly.

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

Governance and meetings: the governance bodies are set. SC meetings organised: logistic, preparation of programme, invitation of experts

Governance and meetings: the governance bodies are set. Kick off meeting organised: logistic, preparation of programme, invitation of experts.

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

Report on the data collection and selection on TB disease and candidate vaccines/treatments

The purpose of this deliverable is to collect all publicly available data on the host-pathogen interaction for TB infection and disease as well as data from preclinical and clinical studies conducted with TB vaccine candidates in the pipeline.

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

First dissemination report

First dissemination report

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

Public web site

Creation of a public web site (strituvad-isct.eu) .

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Websites, patent fillings, videos etc. 2020-04-16

A coherent hierarchical Bayesian model encompassing the virtual and real data sources.

This deliverable brings real and virtual patients models together to relate in a coherent manner the outcome from the in silico and in vivo experiments in the (WP2).

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

Report on the modeling simulation framework able to simulate human immune system dynamics

The UNICT partner has developed through years a computational modeling infrastructure able to simulate the main features and dynamics of the immune system, named UISS (Universal Immune System Simulator). UISS is a multi-scale, multi-organ, three-dimensional agent based simulator of the immune system with an attached module able to simulate the dynamics of specific biological pathways at the molecular level. In this report we describe the extension and the enhancing of the UISS platform to take care of the human immune system at large scale, in order and include the organs that play important role in TB i.e., lungs and the lymph nodes around them.

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16

Dissemination plan

Dissemination plan

Programme: H2020-EU.3.1.5. - Topic(s): SC1-PM-16-2017

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Documents, reports 2020-04-16