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IMCUSTOMEYE SIGNED

IMaging-based CUSTOMised EYE diagnostics

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

IMCUSTOMEYE project word cloud

Explore the words cloud of the IMCUSTOMEYE project. It provides you a very rough idea of what is the project "IMCUSTOMEYE" about.

standard diagnosis annual presbyopia free treatment cataract mechanical ectasia tomography markers vision compact corneal disease prevalent estimate isolated deploy sensitive shape direct validations accurate deformation differences models worldwide optics pressure tools enabled customised acoustic coherence invasive ophthalmology eye intraocular diseases paradigms biomarkers elasticity instrumentation underlie viscoelasticity vivo label puff patient millions risk industrial disciplines patients threatening imcustomeye keratoconus morphological rely diagnostic clinical air screening coupled imaging first time area glaucoma reinforce errors billion optical vibrography leadership dynamic precede stimulated estimates nanosensitive myopia biomechanical refractive predictive hospitals society

Project "IMCUSTOMEYE" data sheet

The following table provides information about the project.

Coordinator	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Spain [ES]
Project website	http://www.imcustomeye.eu/
Total cost	6˙552˙841 €
EC max contribution	5˙931˙669 € (91%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2017-1
Funding Scheme	IA
Starting year	2018
Duration (year-month-day)	from 2018-01-01 to 2021-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS Organization address address: CALLE SERRANO 117 city: MADRID postcode: 28006 website: http://www.csic.es contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	coordinator	1˙457˙423.00
2	INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK INSTYTUT CHEMII FIZYCZNEJ POLSKIEJ AKADEMII NAUK Organization address address: KASPRZAKA 44/52 city: WARSZAWA postcode: 1224 website: http://www.ichf.edu.pl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	PL (WARSZAWA)	participant	979˙000.00
3	THE UNIVERSITY OF LIVERPOOL THE UNIVERSITY OF LIVERPOOL Organization address address: BROWNLOW HILL 765 FOUNDATION BUILDING city: LIVERPOOL postcode: L69 7ZX website: www.liverpool.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LIVERPOOL)	participant	824˙881.00
4	NATIONAL UNIVERSITY OF IRELAND GALWAY NATIONAL UNIVERSITY OF IRELAND GALWAY Organization address address: UNIVERSITY ROAD city: Galway postcode: H91 website: www.nuigalway.ie contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IE (Galway)	participant	820˙413.00
5	IROC SCIENCE TO INNOVATION AG IROC SCIENCE TO INNOVATION AG Organization address address: BAHNHOFSTRASSE 21 city: ZUG postcode: 6300 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (ZUG)	participant	463˙804.00
6	OCULUS OPTIKGERATE GESELLSCHAFT MITBESCHRANKTER HAFTUNG OCULUS OPTIKGERATE GESELLSCHAFT MITBESCHRANKTER HAFTUNG Organization address address: MUNCHHOLZHAUSER STRASE 29 city: WETZLAR postcode: 35582 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (WETZLAR)	participant	286˙328.00
7	OPTIMO MEDICAL AG OPTIMO MEDICAL AG Organization address address: ROBERT WALSER PLATZ 7 city: BIEL postcode: 2503 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (BIEL)	participant	280˙612.00
8	INSTITUTO OFTALMOLOGICO FERNANDEZ-VEGA SL INSTITUTO OFTALMOLOGICO FERNANDEZ-VEGA SL Organization address address: AV DOCTORES FERNANDO VEGA S/N city: OVIEDO ASTURIAS postcode: 33012 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (OVIEDO ASTURIAS)	participant	261˙121.00
9	MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST MOORFIELDS EYE HOSPITAL NHS FOUNDATION TRUST Organization address address: City Road 162 city: LONDON postcode: EC1V 2PD website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	239˙630.00
10	UNIVERSITY COLLEGE LONDON UNIVERSITY COLLEGE LONDON Organization address address: GOWER STREET city: LONDON postcode: WC1E 6BT website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	160˙918.00
11	2 EYES VISION SL 2 EYES VISION SL Organization address address: CALLE BADALONA 17 2 DERECHA city: MADRID postcode: 28034 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (MADRID)	participant	157˙535.00

Map

Project objective

Prevalent eye diseases, such as glaucoma, keratoconus, refractive errors, cataract, myopia and presbyopia, affect millions worldwide, and only in Europe represent over €20 billion annual cost to society. Current screening tools rely on morphological biomarkers based on corneal shape and optics, yet differences in biomechanical properties underlie and precede disease development (i.e. keratoconus, ectasia risk) or affect standard markers (i.e. intraocular pressure in glaucoma). IMCUSTOMEYE will develop new diagnostic paradigms for these vision-threatening conditions, with a direct impact on their treatment. We will deploy new compact, easy-to-use, label-free non-invasive imaging-based instrumentation for direct measurement of corneal biomechanical properties in patients. The technology is based on imaging concepts brought from other disciplines into ophthalmology and, for the first time, applied in patients in vivo. Dynamic corneal imaging based on air-puff stimulated Optical Coherence Tomography corneal deformation and acoustic stimulated phase sensitive and nanosensitive Optical Coherence Tomography corneal vibrography will be coupled to corneal mechanical models to estimate corneal elasticity and viscoelasticity parameters (isolated from other factors). Corneal biomechanical properties will be used as biomarkers for in-depth diagnosis of keratoconus and ectasia risk, and to provide accurate estimates of intraocular pressure in glaucoma diagnosis. Clinical validations in ophthalmology hospitals will demonstrate the diagnostic and treatment predictive potential of the customised optical and biomechanical eye models from patient-specific enabled by the new technology. IMCUSTOMEYE will contribute to more effective, customised treatment of eye diseases and to reinforce industrial leadership in the area of diagnostic imaging in ophthalmology.

Publications

List of publications.
year	authors and title	journal	last update
2018	Eliasy, A., Chen, K. J., Vinciguerra, R., & Elsheikh, A. Novel Intraocular Pressure Measurement Algorithm for Patients with Keratoconus published pages: , ISSN: , DOI:		2020-01-30
2018	Maklad, O., Theofilis, V., & Elsheikh, A. Fluid Structure Interaction (FSI) Simulation Of the human eye under the air puff tonometry using Computational Fluid Dynamics (CFD) published pages: , ISSN: , DOI:		2020-01-30
2018	J. Birkenfeld, A. Ramier, B. Tavakol, S. Marcos and S. Yun Assessment of ocular mechanical resonances using phase-sensitive OCT and frequency-domain air puff stimulation published pages: , ISSN: , DOI:		2020-01-30
2018	Elsheikh, A., Eliasy, A., Chen, K. J., & Vinciguerra, R. Obtaining biomechanical properties of corneal tissue in-vivo using a non-contact method published pages: , ISSN: , DOI:		2020-01-30
2019	Ewa Maczynska, Karol Karnowski, Krzysztof Szulzycki, Monika Malinowska, Hubert Dolezyczek, Artur Cichanski, Maciej Wojtkowski, Bartlomiej Kaluzny, Ireneusz Grulkowski Assessment of the influence of viscoelasticity of cornea in animal ex vivo model using air-puff optical coherence tomography and corneal hysteresis published pages: e201800154, ISSN: 1864-063X, DOI: 10.1002/jbio.201800154	Journal of Biophotonics 12/2	2020-01-30
2018	A. Curatolo, J. Birkenfeld, J. A. Germann, A. de Castro, G. Muralidharan, M. Velasco, E. MartÃnez, and S. Marcos Customised optical coherence tomography system for corneal deformation imaging on multiple meridians published pages: , ISSN: , DOI:		2020-01-30
2018	Eliasy, A., Zhou, D., Studer, H., Boote, C., & Elsheikh, A. Biomechanics of the Eye _ Chapter 6. Material properties of the human cornea: anisotropy published pages: , ISSN: , DOI:	Material properties of the human cornea: anisotropy	2020-01-30
2018	Eliasy, A., Elsheikh, A., & Chen, K. -J. Intraocular Pressure Measurement Pre- and Post Refractive Surgery Using GAT and CorVis ST bIOP Algorithm published pages: , ISSN: , DOI:		2020-01-30
2018	Ryan McAuley, A. Nolan, K. Larin, M. Singh, S. Alexandrov, Martin Leahy Background Subtraction Vs Highpass filtering in phase sensitive Optica Coherence Tomography published pages: , ISSN: , DOI:	Bi-annual Biophotonics and Imaging Summer School (BIGSS\'18)	2020-01-30

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