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EASYFISH SIGNED

Development of a new biomolecule to better control reproduction in fish

Total Cost €

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EC-Contrib. €

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Partnership

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 Outcomes and results

 EASYFISH project word cloud

Explore the words cloud of the EASYFISH project. It provides you a very rough idea of what is the project "EASYFISH" about.

binding    reliably    tool    antibody    circulating    lh    fragment    ovulation    consumers    sustainable    rp01    fsh    fertilized    environment    induce    monoclonal    manipulations    ovine    endogenous    world    species    trout    spontaneously    conventional    contrast    class    natural    captivity    repropharm    hormones    potentiate    special    injected    potentiating    farming    operations    porcine    females    induces    marine    soon    stimulate    mammals    spontaneous    bovine    first    exogenous    reproduction    polyovulating    fish    oocyte    reproductive    spermatogenesis    efficiency    34    vet    rp001    rate    issue    steroidogenic    hatchery    efficacy    therapies    freshwater    market    egg    salmon    8    hormone    male    eggs    bass    innovative    occursin    rat    female    farmed    hormonal    injection    efficient    source    disrupting    supplies    ie    spermiation    solution    treatment    added    carp    consumption    maturation    fishing    free    sea    males    bream    treatments    nevertheless    acts   

Project "EASYFISH" data sheet

The following table provides information about the project.

Coordinator		 REPROPHARM VET 

Organization address
address: CENTRE INRA VAL DE LOIRE SITE DE TOURS
city: NOUZILLY
postcode: 37380
website: n.a.

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.
 Coordinator Country France [FR]
 Project website http://www.repropharmvet.com
 Total cost 71˙429 €
 EC max contribution 50˙000 € (70%)
 Programme 1. H2020-EU.3. (PRIORITY 'Societal challenges)
2. H2020-EU.2.3. (INDUSTRIAL LEADERSHIP - Innovation In SMEs)
3. H2020-EU.2.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies)
 Code Call H2020-SMEInst-2018-2020-1
 Funding Scheme SME-1
 Starting year 2018
 Duration (year-month-day) from 2018-08-01   to  2019-01-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    REPROPHARM VET FR (NOUZILLY) coordinator 50˙000.00

Map

 Project objective

'Fish farming is growing at 8% a year and will soon be the main source of fish for consumers. It supplies more than 34% of the world's fish consumption. Nevertheless, due to captivity environment some species have reproduction problems with no spontaneous ovulation in females and no spermiation in males. In some farmed freshwater species (ie, Carp, Salmon, Trout) and marine species (ie, Sea bass, Sea bream) the growth phase of reproductive development occursin captivity in contrast to oocyte maturation and ovulation in females, and spermiation in males that do not occur spontaneously. This problem requires exogenous hormonal therapies which are the only way to produce fertilized eggs reliably. In other species, these hormonal manipulations are used only as a management tool to enhance the efficiency of egg production, increase spermiation and facilitate hatchery operations. ReproPharm Vet developed a first in class monoclonal antibody RP01 and its fragment RP001, that are able to potentiate the activity of endogenous FSH and LH in mammals such as rat, bovine, ovine, porcine species. RP001 fragment can induce ovulation in female and stimulate spermatogenesis in male without any exogenous hormone injection. When injected, it acts directly on circulating FSH and LH hormones by binding to them and potentiating their activity. RP001 is more effective than conventional hormonal treatments it induces a better ovulation rate in polyovulating species and a better steroidogenic response in every species. Treatment with potentiating RP001 would be a highly innovative solution, hormone free, which could be a disrupting product in fishing market if we demonstrate its efficacy on fish FSH and LH. Its added value would be a more efficient method to induce ovulation and spermatogenesis without any exogenous hormone injection. RP001 would be a 'must-have' product to better control fish reproduction in a natural and sustainable way that represents a special issue on environment. '

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The information about "EASYFISH" are provided by the European Opendata Portal: CORDIS opendata.

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