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GROWTH SIGNED

Research and Training in Early Life Nutrition to Prevent Disease

Total Cost €

EC-Contrib. €

Partnership

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GROWTH project word cloud

Explore the words cloud of the GROWTH project. It provides you a very rough idea of what is the project "GROWTH" about.

pathological harmful analytical train microbiota inflammatory industrial enhances insights critical bio immature metabolomics metabolic diagnostics sepsis multidisciplinary mediated involve period area mortality cohort microbiome doctorates oriented academic sciences neonatal proposes homeostasis intestinal necrotizing reduce nutritional tools risk infants later interaction personalized reducing preterm enterocolitis interactions host survival immune network informatics basic dysbiosis gut function diseases interventions elucidating life nutrition biomarker business prevent limits mediators innovative numberof attempt young barrier plays participation lack efficacy interplay clinical disease expertise chronic shortening training neonates disturbed

Project "GROWTH" data sheet

The following table provides information about the project.

Coordinator	DSCN RESEARCH B.V. Organization address address: KLOKKENBERGWEG 8 city: AMSTERDAM postcode: 1101 AS website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Netherlands [NL]
Total cost	2˙183˙583 €
EC max contribution	2˙183˙583 € (100%)
Programme	1. H2020-EU.1.3.1. (Fostering new skills by means of excellent initial training of researchers)
Code Call	H2020-MSCA-ITN-2018
Funding Scheme	MSCA-ITN-EID
Starting year	2019
Duration (year-month-day)	from 2019-06-01 to 2023-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	DSCN RESEARCH B.V. DSCN RESEARCH B.V. Organization address address: KLOKKENBERGWEG 8 city: AMSTERDAM postcode: 1101 AS website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	coordinator	265˙619.00
2	UNIVERSITATSKLINIKUM BONN UNIVERSITATSKLINIKUM BONN Organization address address: VENUSBERG-CAMPUS 1 city: BONN postcode: 53127 website: www.ukb.uni-bonn.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BONN)	participant	505˙576.00
3	IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE Organization address address: SOUTH KENSINGTON CAMPUS EXHIBITION ROAD city: LONDON postcode: SW7 2AZ website: http://www.imperial.ac.uk/ contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (LONDON)	participant	303˙172.00
4	RECKITT BENCKISER PLC RECKITT BENCKISER PLC Organization address address: 103-105 BATH ROAD city: SLOUGH postcode: SL1 3UH website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (SLOUGH)	participant	303˙172.00
5	CHERRY BIOTECH CHERRY BIOTECH Organization address address: 6 RUE GURVAND city: RENNES postcode: 35000 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (RENNES)	participant	274˙802.00
6	ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM Organization address address: MEIBERGDREEF 15 city: AMSTERDAM postcode: 1105AZ website: www.amc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	265˙619.00
7	STICHTING VUMC STICHTING VUMC Organization address address: DE BOELELAAN 1117 city: AMSTERDAM postcode: 1081 HV website: www.vumc.nl contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	NL (AMSTERDAM)	participant	265˙619.00

Map

Project objective

The interplay between nutrition, gut microbiota, and its large numberof metabolic and immune mediators plays an essential role in the development of gut immune homeostasis in early life. This interaction needs to be better understood because a disturbed immune function in the neonatal period is harmful for neonatal survival and enhances the risk of chronic inflammatory disease later in life. In particular, preterm infants have an immature gut and an associated intestinal state of dysbiosis, which limits the efficacy of nutritional interventions to 1) support early life nutrition, 2) prevent sepsis and conditions such as necrotizing enterocolitis and intestinal failure, and 3) reduce the risk of chronic inflammatory diseases mediated by the gut. A major barrier to elucidating the critical nutritional-host-microbiome interactions and reducing neonatal mortality is the lack of expertise in this rapidly emerging area of metabolomics. We therefore proposes a multidisciplinary approach making use of a large-scale pre-existing clinical cohort of neonates, and state of the art analytical and bio-informatics tools. GROWTH is an Innovative Training Network focused on European Industrial Doctorates that aims to train young business-oriented researchers in developing pathological insights, biomarker diagnostics and personalized nutritional interventions for intestinal failure in neonates and preterm infants. As a multidisciplinary consortium that will involve the participation of 7 non-academic and 5 academic partners in the life sciences field and will attempt shortening the path from basic research to clinical applications.

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