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ReduceFear SIGNED

Fear reduction strategies relevant for exposure therapy: Devaluation and extinction learning in anxiety disorder patients and their neurobiological basis

Total Cost €

EC-Contrib. €

Partnership

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ReduceFear project word cloud

Explore the words cloud of the ReduceFear project. It provides you a very rough idea of what is the project "ReduceFear" about.

networking excessive stress aversiveness exposure disorder msca play fear fears reducefear me building standard augmentation clinical understudied ambition ptsd professor traumatic position blocks communication successfully experimental benefit self hands assistant reduce concurrently personalization anxiety deficits writing gap devaluation grant 50 host examine neurobiological teaching gold opportunity train strategies post independent perceived extinction pi expectation disorders postdoc leadership scientific expertise mechanisms treatment fragile patients threat neuroimaging maturity competences transfer training reducing group provides psychology skills robustly reduces harm my optimization therapies therapy line first time psychologist dysfunctional learning

Project "ReduceFear" data sheet

The following table provides information about the project.

Coordinator	KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: OUDE MARKT 13 city: LEUVEN postcode: 3000 website: www.kuleuven.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Belgium [BE]
Total cost	178˙320 €
EC max contribution	178˙320 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2018
Funding Scheme	MSCA-IF-EF-ST
Starting year	2019
Duration (year-month-day)	from 2019-10-01 to 2023-10-01

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	KATHOLIEKE UNIVERSITEIT LEUVEN KATHOLIEKE UNIVERSITEIT LEUVEN Organization address address: OUDE MARKT 13 city: LEUVEN postcode: 3000 website: www.kuleuven.be contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	BE (LEUVEN)	coordinator	178˙320.00

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Project objective

My ambition is to become an independent PI and clinical psychologist with a novel research line focusing on treatment optimization and personalization for anxiety disorders and post-traumatic stress disorder (PTSD). The MSCA-IF will provide the essential building blocks for this research line, and provides the opportunity to develop generic skills necessary to transfer from a postdoc position to an Assistant Professor position. Training through research: I will bring my expertise in neuroimaging and clinical psychology to the host, and the host’ PI will train me in experimental task development. The aim of ReduceFear is to examine fear reduction strategies that play a role in exposure therapy, the gold standard therapy for anxiety disorders and PTSD. These disorders are highly common, and up to 50% of patients do not benefit from the therapy. The project will concurrently assess (a) extinction learning, a process that reduces the over-expectation of harm but is highly fragile and dysfunctional in anxiety patients, and (b) threat (US) devaluation, a highly-understudied process that has potential to more robustly reduce excessive fears by reducing the perceived aversiveness of the threat. Overall objective: to examine for the first time (1) the neurobiological mechanisms of US devaluation compared to extinction learning to identify (pre)clinical targets for therapy augmentation, and (2) US devaluation mechanisms in patients with anxiety disorders. If anxiety patients not show any deficits in US devaluation, exposure-based therapies may be adapted to enhance focus on US devaluation. Hands-on training: As identified by a Gap Analysis, I will work on the following competences in order to reach scientific maturity and to successfully lead my own research group in the future: (1) Networking, (2) Time-management / Self-management, (3) Grant Writing, (4) Leadership, (5) Teaching, and (6) Communication/Dissemination.

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The information about "REDUCEFEAR" are provided by the European Opendata Portal: CORDIS opendata.