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INDITOL SIGNED

Individual variation in tolerance of hypoxia and high temperatures in teleost fish: mechanisms and implications

Total Cost €

0

EC-Contrib. €

0

Partnership

0

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 INDITOL project word cloud

Explore the words cloud of the INDITOL project. It provides you a very rough idea of what is the project "INDITOL" about.

o2    persist    document    offs    fish    capacity    global    techniques    functional    fishes    respirometry    coastal    trait    respiratory    species    tolerant    juveniles    relative    acute    underlying    severity    hypoxia    suffer    individuals    vivo    frequency    respiring    whereby    function    innovative    indicate    traits    cardiorespiratory    sub    performance    mode    tissues    exercise    reveal    populations    emblematic    cross    bass    environmental    200    warming    mechanisms    intrinsic    action    world    sufficient    endpoints    assays    trades    trade    experiments    variation    mitochondrial    existence    dependencies    marine    share    physiology    persistence    systematically    rate    lethal    insights    husbandry    valuable    efficiency    episodes    advantageous    oxidative    nature    tolerance    multiple    comprise    off    data    explored    population    correlations    physiological    tendency    animal    individual    vary    stress    stressful    fresh    sea    stressors    depends    relates   

Project "INDITOL" data sheet

The following table provides information about the project.

Coordinator
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS 

Organization address
address: RUE MICHEL ANGE 3
city: PARIS
postcode: 75794
website: www.cnrs.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 184˙707 €
 EC max contribution 184˙707 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2018
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2019
 Duration (year-month-day) from 2019-04-15   to  2021-04-14

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS FR (PARIS) coordinator 184˙707.00

Map

 Project objective

Episodes of hypoxia and acute warming can be major environmental stressors for coastal marine fishes, that will increase in frequency and severity with global change. Hypoxia and warming share a common physiological mode of action in fishes, both challenge the animal's capacity to provide sufficient O2 to respiring tissues. Within fish populations, individuals may vary in tolerance of these stressors; the existence of such variation can define the ability of populations to persist in a more stressful world. Moreover, when individuals vary in tolerance, underlying physiological mechanisms for variation can be explored. Understanding of mechanisms is very valuable because the persistence of variation in tolerance, within populations, may indicate that there are functional trade-offs, whereby being tolerant is not systematically advantageous but has costs. Using controlled experiments on European sea bass, an emblematic coastal species, my aims are to: 1) document variation in sub-lethal tolerance of hypoxia and acute warming in a population of 200 juveniles, and reveal cross-tolerance; 2) demonstrate that relative tolerance depends upon each individual’s intrinsic respiratory physiology; 3) investigate how tolerance relates to underlying mitochondrial efficiency, and 4) evaluate whether tolerance trades-off against important individual traits, as growth rate and tendency to suffer from oxidative stress. The experiments comprise innovative state-of-the-art techniques of sea bass husbandry; in-vivo respirometry and exercise performance; sub-lethal tolerance endpoints based upon cardiorespiratory performance, and assays of mitochondrial function in fresh tissues. Data will be analyzed to reveal trait correlations and dependencies, and existence of functional trade-offs. These multiple level studies, to reveal functional trade-offs of tolerance to hypoxia and warming, will provide novel and important insights into the nature of fish populations in a more stressful world.

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