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GENE-SWitCH SIGNED

The regulatory GENomE of SWine and CHicken: functional annotation during development

Total Cost €

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EC-Contrib. €

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Partnership

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 GENE-SWitCH project word cloud

Explore the words cloud of the GENE-SWitCH project. It provides you a very rough idea of what is the project "GENE-SWitCH" about.

chicken    data    dynamics    audience    adult    true    space    excellence    resolution    full    brings    diet    breeding    standards    considerably    models    genomic    post    epigenome    perturbations    community    conform    sectors    productions    until    stakeholders    underpinning    pigs    persist    synergy    annotations    outreach    pioneered    nutritional    validated    expression    edge    ongoing    time    cutting    fetus    weaning    tissues    predictive    innovative    environmental    genomes    sequences    annotation    switches    evaluation    life    industry    translation    integrate    activation    status    pan    commercial    animal    datasets    maternal    faang    creation    monogastric    biotech    strategies    qtl    plan    functional    genetic    academic    switch    valuable    paving    embryo    poultry    sustainable    benefit    co    varies    world    genome    panel    populations    epigenetic    shared    species    add    representing    global    effort    variation    gene    farm    pig    influence   

Project "GENE-SWitCH" data sheet

The following table provides information about the project.

Coordinator
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT 

Organization address
address: Rue De L'Universite 147
city: PARIS CEDEX 07
postcode: 75338
website: www.inra.fr

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country France [FR]
 Total cost 5˙999˙891 €
 EC max contribution 5˙999˙886 € (100%)
 Programme 1. H2020-EU.3.2.1.1. (Increasing production efficiency and coping with climate change, while ensuring sustainability and resilience)
2. H2020-EU.3.2.3.1. (Developing sustainable and environmentally-friendly fisheries)
 Code Call H2020-SFS-2018-2
 Funding Scheme RIA
 Starting year 2019
 Duration (year-month-day) from 2019-07-01   to  2023-06-30

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT FR (PARIS CEDEX 07) coordinator 1˙195˙073.00
2    WAGENINGEN UNIVERSITY NL (WAGENINGEN) participant 971˙783.00
3    THE UNIVERSITY OF EDINBURGH UK (EDINBURGH) participant 905˙523.00
4    EUROPEAN MOLECULAR BIOLOGY LABORATORY DE (HEIDELBERG) participant 710˙478.00
5    DIAGENODE BE (SERAING) participant 548˙000.00
6    INSTITUT DE RECERCA I TECNOLOGIA AGROALIMENTARIES ES (CALDES DE MONTBUI BARCELONA) participant 509˙992.00
7    HENDRIX GENETICS RESEARCH,TECHNOLOGY & SERVICES BV NL (BOXMEER) participant 343˙743.00
8    UPPSALA UNIVERSITET SE (UPPSALA) participant 287˙500.00
9    INRA TRANSFERT SAS FR (PARIS) participant 209˙750.00
10    EUROPEAN FORUM OF FARM ANIMAL BREEDERS NL (WAGENINGEN) participant 197˙357.00
11    FEDERAZIONE EUROPEA DI ZOOTECNICA IT (ROMA) participant 120˙687.00

Map

 Project objective

GENE-SWitCH aims to deliver new underpinning knowledge on the functional genomes of two main monogastric farm species (pig and chicken) and to enable immediate translation to the pig and poultry sectors. The activation status of functional genome sequences varies across time and space, and in response to environmental perturbations. In full coordination and synergy with global effort and ongoing projects of the Functional Annotation of ANimal Genomes (FAANG) community, we will characterize the dynamics (“switches”) of the functional genome from embryo (chicken) and fetus (pig) to adult life by targeting a panel of tissues relevant to sustainable production. New expression QTL data in pigs and existing high-resolution QTL data in chicken will be used for developing innovative genomic predictive models that integrate functional annotations, and these models will be validated in commercial pig and poultry populations. In addition, nutritional epigenetic data will allow evaluation of the influence of maternal diet on the epigenome of the pig fetus and whether such effects persist until post-weaning. These open-shared datasets will conform fully with FAANG standards and add valuable knowledge on genetic and epigenetic variation of functional elements to FAANG. A comprehensive plan of dissemination and outreach activities to a large audience of stakeholders will be implemented. The GENE-SWitCH consortium brings together partners representing pan-European excellence (including the academic institutions which pioneered FAANG) and world-leading animal breeding and biotech industry in a true co-creation effort. Overall, GENE-SWitCH will contribute to the global FAANG effort considerably, demonstrate how functional annotation of genomes can foster the advancement of genomic selection for immediate benefit to the breeding industry, and produce cutting-edge research paving the way to new studies and strategies for sustainable productions.

 Deliverables

List of deliverables.
GENE-SWitCH Data Management Plan Open Research Data Pilot 2020-04-25 13:33:44
Outreach, dissemination, and training plan Documents, reports 2020-04-25 13:33:44

Take a look to the deliverables list in detail:  detailed list of GENE-SWitCH deliverables.

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