The page lists 11 projects related to the topic "brca2".
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1 | Pharmcophore-DOS | Pharmacophore guided diversity-oriented synthesis and its application in discovering inhibitors of protein-protein interactions between RAD51 and BRCA2 | 2015 |
2 | BRCA2Interact | Structural and biochemical characterization of pre-recombination complexes | 2015 |
3 | TARLOOP | R-loops as a major modulator of transcription-associated recombination and chromatin dynamics | 2015 |
4 | DNA2REPAIR | DNA strand break repair and links to human disease | 2015 |
5 | SYNVIA | Synthetic viability of homologous recombination-deficient cancers | 2016 |
6 | BRCANCER | A novel approach for modeling development of breast cancer | 2016 |
7 | SYNTRAIN | Targeting SYNthetic lethal interactions for new cancer treatments TRAINing network | 2016 |
8 | FANCODRUG | Reactivation of the Fanconi anemia-BRCA pathway in cells carrying patient-derived missense mutations: finding a drug to cure Fanconi anemia | 2017 |
9 | DREMATURE | DNA repair mechanisms and therapy resistance of BRCA2-deficient cancers | 2018 |
10 | PARPinhibit | A systems biology approach to tackle PARP-inhibitors resistance and identify novel therapeutic targets to overcome it | 2020 |
11 | BRCAstem | Monitoring cancer stem cell dynamics and therapeutic response in BRCA2-deficient breast tumour cells | 2020 |