MAMI SIGNED
The Power of Maternal Microbes on Infant Health
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0MAMI project word cloud
Explore the words cloud of the MAMI project. It provides you a very rough idea of what is the project "MAMI" about.
Project "MAMI" data sheet
The following table provides information about the project.
| Coordinator |
AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Organization address contact info |
| Coordinator Country | Spain [ES] |
| Project website | http://www.mamiproject.eu |
| Total cost | 1˙499˙979 € |
| EC max contribution | 1˙499˙979 € (100%) |
| Programme |
1. H2020-EU.1.1. (EXCELLENT SCIENCE - European Research Council (ERC)) |
| Code Call | ERC-2014-STG |
| Funding Scheme | ERC-STG |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-06-01 to 2020-12-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS | ES (MADRID) | coordinator | 1˙499˙979.00 |
Map
Project objective
Recent reports suggest that early microbial colonization has an important role for in promoting health. This may contribute to reduce the risk of chronic diseases such as obesity, allergies and inflammatory conditions. Advances in understanding host-microbe interactions imply that maternal microbiota plays a crucial role on health programming. This process begins in utero and it is modulated by mode of delivery and diet. My research has shown that i) specific shifts in milk microbial composition are associated with lactation time and mode of delivery, ii) milk microbes drive the infant microbiota composition; iii) maternal microbiota dysbiosis may be transferred to the infant. However, factors defining maternal microbiota and its biological role upon infant’s health are not yet fully understood. Hence, this project aims to characterize maternal microbes to be transferred to neonates and determine their function in infant health programming. The specific aims are:(1) understanding how the maternal microbiome is influenced by host and environmental factors;(2) characterizing the microbial core and bioactive compounds transmitted to the offspring mainly via breastfeeding and their key roles in the microbial modulation and host response;(3) understanding the interactions among breast milk bioactive compounds and their role in infant health;(4) shedding light on how maternal microbes influence the infant immune system & (5)development of new dietary strategies and therapies based on microbial replacement and modulation. To achieve these objectives, a systems biology approach by means of state-of-the-art techniques and new methodologies based on subpopulation enrichment by flow cytometer-sorter to study host–microbe interactions will be used. Results obtained will demonstrate the interaction between infant nutrition, microbes and host response in early life and its key role in health programming, enabling new applications in the field of personalized nutrition & medicine.
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2019 |
Adrián Cortés-MartÃn, MarÃa Romo-Vaquero, Izaskun GarcÃa-Mantrana, Ana RodrÃguez-Varela, MarÃa Carmen Collado, Juan Carlos EspÃn, MarÃa Victoria Selma Urolithin Metabotypes can Anticipate the Different Restoration of the Gut Microbiota and Anthropometric Profiles during the First Year Postpartum published pages: 2079, ISSN: 2072-6643, DOI: 10.3390/nu11092079 |
Nutrients 11/9 | 2020-02-06 |
| 2019 |
Anna Parra-Llorca, MarÃa Gormaz, Sheila Lorente-Pozo, Maria Cernada, Ana GarcÃa-Robles, Isabel Torres-Cuevas, Julia Kuligoswki, Maria Carmen Collado, Eva Serna, Máximo Vento Impact of Donor Human Milk in the Preterm Very Low Birth Weight Gut Transcriptome Profile by Use of Exfoliated Intestinal Cells published pages: 2677, ISSN: 2072-6643, DOI: 10.3390/nu11112677 |
Nutrients 11/11 | 2020-02-06 |
| 2019 |
Izaskun GarcÃa-Mantrana, Marta Calatayud, MarÃa Romo-Vaquero, Juan Carlos EspÃn, MarÃa V. Selma, MarÃa Carmen Collado Urolithin Metabotypes Can Determine the Modulation of Gut Microbiota in Healthy Individuals by Tracking Walnuts Consumption over Three Days published pages: 2483, ISSN: 2072-6643, DOI: 10.3390/nu11102483 |
Nutrients 11/10 | 2020-02-06 |
| 2018 |
Carlos Gómez-Gallego, Jose Morales, Daniel Monleón, Elloise du Toit, Himanshu Kumar, Kaisa Linderborg, Yumei Zhang, Baoru Yang, Erika Isolauri, Seppo Salminen, Maria Collado Human Breast Milk NMR Metabolomic Profile across Specific Geographical Locations and Its Association with the Milk Microbiota published pages: 1355, ISSN: 2072-6643, DOI: 10.3390/nu10101355 |
Nutrients 10/10 | 2020-02-06 |
| 2019 |
Izaskun GarcÃa-Mantrana, Cristina Alcántara, Marta Selma-Royo, Alba Boix-Amorós, Majda Dzidic, Jose Gimeno-Alcañiz, Isabel Úbeda-Sansano, Ignacio Sorribes-Monrabal, Ramón Escuriet, Fernando Gil-Raga, Anna Parra-Llorca, Cecilia MartÃnez-Costa, MarÃa Carmen Collado MAMI: a birth cohort focused on maternal-infant microbiota during early life published pages: , ISSN: 1471-2431, DOI: 10.1186/s12887-019-1502-y |
BMC Pediatrics 19/1 | 2020-02-06 |
| 2019 |
Raul Cabrera-Rubio, Clemens Kunz, Silvia Rudloff, Izaskun GarcÃa-Mantrana, Elena Crehuá-Gaudiza, Cecilia MartÃnez-Costa, M. Carmen Collado Association of Maternal Secretor Status and Human Milk Oligosaccharides With Milk Microbiota published pages: 256-263, ISSN: 0277-2116, DOI: 10.1097/MPG.0000000000002216 |
Journal of Pediatric Gastroenterology and Nutrition 68/2 | 2020-02-06 |
| 2018 |
Majda Dzidic, Thomas Abrahamsson, Alejandro Artacho, Maria Carmen Collado, Alex Mira, Maria C Jenmalm Oral microbiota maturation during the first 7 years of life in relation to allergy development published pages: , ISSN: 0105-4538, DOI: 10.1111/all.13449 |
Allergy | 2019-07-22 |
| 2016 |
Izaskun Garcia-Mantrana, Maria Carmen Collado Obesity and overweight: Impact on maternal and milk microbiome and their role for infant health and nutrition published pages: 1865-1875, ISSN: 1613-4125, DOI: 10.1002/mnfr.201501018 |
Molecular Nutrition & Food Research 60/8 | 2019-07-22 |
| 2017 |
Alba Boix-Amorós, Cecilia Martinez-Costa, Amparo Querol, Maria Carmen Collado, Alex Mira Multiple Approaches Detect the Presence of Fungi in Human Breastmilk Samples from Healthy Mothers published pages: , ISSN: 2045-2322, DOI: 10.1038/s41598-017-13270-x |
Scientific Reports 7/1 | 2019-07-22 |
| 2016 |
Himanshu Kumar, Elloise du Toit, Amruta Kulkarni, Juhani Aakko, Kaisa M. Linderborg, Yumei Zhang, Mark P. Nicol, Erika Isolauri, Baoru Yang, Maria C. Collado, Seppo Salminen Distinct Patterns in Human Milk Microbiota and Fatty Acid Profiles Across Specific Geographic Locations published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2016.01619 |
Frontiers in Microbiology 7 | 2019-07-22 |
| 2018 |
Izaskun Garcia-Mantrana, Marta Selma-Royo, Cristina Alcantara, MarÃa C. Collado Shifts on Gut Microbiota Associated to Mediterranean Diet Adherence and Specific Dietary Intakes on General Adult Population published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2018.00890 |
Frontiers in Microbiology 9 | 2019-07-22 |
| 2016 |
Alba Boix-Amorós, Maria C. Collado, Alex Mira Relationship between Milk Microbiota, Bacterial Load, Macronutrients, and Human Cells during Lactation published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2016.00492 |
Frontiers in Microbiology 7 | 2019-07-22 |
| 2016 |
Izaskun GarcÃa-Mantrana, Bibiana Bertua, Cecilia MartÃnez-Costa, Maria Carmen Collado Perinatal nutrition: How to take care of the gut microbiota? published pages: 3-16, ISSN: 2352-9393, DOI: 10.1016/j.yclnex.2016.02.002 |
Clinical Nutrition Experimental 6 | 2019-07-22 |
| 2016 |
Carlos Gomez-Gallego, Izaskun Garcia-Mantrana, Seppo Salminen, MarÃa Carmen Collado The human milk microbiome and factors influencing its composition and activity published pages: 400-405, ISSN: 1744-165X, DOI: 10.1016/j.siny.2016.05.003 |
Seminars in Fetal and Neonatal Medicine 21/6 | 2019-07-22 |
| 2018 |
Majda Dzidic, Alba Boix-Amorós, Marta Selma-Royo, Alex Mira, Maria Collado Gut Microbiota and Mucosal Immunity in the Neonate published pages: 56, ISSN: 2076-3271, DOI: 10.3390/medsci6030056 |
Medical Sciences 6/3 | 2019-07-22 |
| 2018 |
Anna Parra-Llorca, MarÃa Gormaz, Cristina Alcántara, MarÃa Cernada, Antonio Nuñez-Ramiro, Máximo Vento, Maria C. Collado Preterm Gut Microbiome Depending on Feeding Type: Significance of Donor Human Milk published pages: , ISSN: 1664-302X, DOI: 10.3389/fmicb.2018.01376 |
Frontiers in Microbiology 9 | 2019-07-22 |
| 2016 |
Maria Carmen Collado, Samuli Rautava, Juhani Aakko, Erika Isolauri, Seppo Salminen Human gut colonisation may be initiated in utero by distinct microbial communities in the placenta and amniotic fluid published pages: 23129, ISSN: 2045-2322, DOI: 10.1038/srep23129 |
Scientific Reports 6 | 2019-07-22 |
| 2018 |
Majda Dzidic, Maria C. Collado, Thomas Abrahamsson, Alejandro Artacho, Malin Stensson, Maria C. Jenmalm, Alex Mira Oral microbiome development during childhood: an ecological succession influenced by postnatal factors and associated with tooth decay published pages: 2292-2306, ISSN: 1751-7362, DOI: 10.1038/s41396-018-0204-z |
The ISME Journal 12/9 | 2019-07-22 |
| 2017 |
Carlos Gómez-Gallego, Himanshu Kumar, Izaskun GarcÃa-Mantrana, Elloise du Toit, Jukka-Pekka Suomela, Kaisa M. Linderborg, Yumei Zhang, Erika Isolauri, Baoru Yang, Seppo Salminen, M. Carmen Collado Breast Milk Polyamines and Microbiota Interactions: Impact of Mode of Delivery and Geographical Location published pages: 184-190, ISSN: 0250-6807, DOI: 10.1159/000457134 |
Annals of Nutrition and Metabolism 70/3 | 2019-07-22 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "MAMI" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "MAMI" are provided by the European Opendata Portal: CORDIS opendata.