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R2R Biofluidics SIGNED

Large scale micro-and nanofabrication technologies for bioanalytical devices based on R2R imprinting

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

R2R Biofluidics project word cloud

Explore the words cloud of the R2R Biofluidics project. It provides you a very rough idea of what is the project "R2R Biofluidics" about.

demonstrators fabrication sensitivity neurons vitro benefit r2r formats technologies screening ivd quantities nanoimprinting complementary complete electronics microfluidic microtiter imprinted micro surfaces nanoscale neuron food throughput microfluidics flexible lines demonstrator industry optics graphical showing chain channels care patterns interconnected time diagnostics microstructured standard respect productivity unrivalled chip precise fabricated notably manufacturing mature structures techniques microscope device biofluidics discovery capacity commercial volume lower diagnostic nano core lab assays point printing types drug combination bioanalytical prices biofunctionalized roller slides first combined suitable roll reduce thanks plate alignment nanostructures adopting realization optical consist

Project "R2R Biofluidics" data sheet

The following table provides information about the project.

Coordinator	JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH Organization address address: LEONHARDSTRASSE 59 city: GRAZ postcode: 8010 website: www.joanneum.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Austria [AT]
Project website	http://www.r2r-biofluidics.eu
Total cost	7˙677˙557 €
EC max contribution	6˙421˙672 € (84%)
Programme	1. H2020-EU.2.1.2.1. (Developing next generation nanomaterials, nanodevices and nanosystems)
Code Call	H2020-NMP-PILOTS-2014
Funding Scheme	IA
Starting year	2015
Duration (year-month-day)	from 2015-02-01 to 2019-07-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH Organization address address: LEONHARDSTRASSE 59 city: GRAZ postcode: 8010 website: www.joanneum.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	coordinator	2˙395˙932.00
2	FUNDACION TECNALIA RESEARCH & INNOVATION FUNDACION TECNALIA RESEARCH & INNOVATION Organization address address: PARQUE CIENTIFICO Y TECNOLOGICO DE BIZKAIA, ASTONDO BIDEA, EDIFICIO 700 city: DERIO BIZKAIA postcode: 48160 website: www.tecnalia.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (DERIO BIZKAIA)	participant	675˙563.00
3	INMOLD AS INMOLD AS Organization address address: SAVSVINGET 4 city: HORSHOLM postcode: 2970 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DK (HORSHOLM)	participant	648˙579.00
4	MICRO RESIST TECHNOLOGY GESELLSCHAFT FUER CHEMISCHE MATERIALIEN SPEZIELLER PHOTORESISTSYSTEME MBH MICRO RESIST TECHNOLOGY GESELLSCHAFT FUER CHEMISCHE MATERIALIEN SPEZIELLER PHOTORESISTSYSTEME MBH Organization address address: Koepenicker Strasse 325 city: BERLIN postcode: 12555 website: www.microresist.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (BERLIN)	participant	557˙375.00
5	BIONANONET FORSCHUNGSGESELLSCHAFT MBH BIONANONET FORSCHUNGSGESELLSCHAFT MBH Organization address address: STEYRERGASSE 17 city: GRAZ postcode: 8010 website: www.bionanonet.at contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	participant	419˙779.00
6	EV GROUP E. THALLNER GMBH EV GROUP E. THALLNER GMBH Organization address address: DI ERICH THALLNER STRASSE 1 city: ST FLORIAN AM INN postcode: 4782 website: www.evgroup.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (ST FLORIAN AM INN)	participant	374˙268.00
7	GENSPEED BIOTECH GMBH GENSPEED BIOTECH GMBH Organization address address: GEWERBEPARK 2 city: RAINBACH IM MUHLKREIS postcode: 4261 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (RAINBACH IM MUHLKREIS)	participant	357˙897.00
8	Innovative Technologies in Biological Systems Innovative Technologies in Biological Systems Organization address address: PARQUE TECNOLOGICO DE BIZKAIA 502-1 city: Derio postcode: 48160 website: www.innoprot.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	ES (Derio)	participant	295˙515.00
9	BIFLOW SYSTEMS GMBH BIFLOW SYSTEMS GMBH Organization address address: TECHNOLOGIE-CAMPUS 1 city: CHEMNITZ postcode: 9126 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (CHEMNITZ)	participant	247˙725.00
10	BIONIC SURFACE TECHNOLOGIES GMBH BIONIC SURFACE TECHNOLOGIES GMBH Organization address address: LIEBENAUER HAUPTSTRASSE 2-6 city: GRAZ postcode: 8041 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (GRAZ)	participant	225˙050.00
11	SCIENION AG SCIENION AG Organization address address: OTTO HAHN STRASSE 15 city: DORTMUND postcode: 44227 website: www.scienion.de contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (DORTMUND)	participant	197˙553.00
12	GREINER BIO-ONE DIAGNOSTICS GMBH GREINER BIO-ONE DIAGNOSTICS GMBH Organization address address: GEWERBEPARK 2 city: RAINBACH IM MUHLKREIS postcode: 4261 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (RAINBACH IM MUHLKREIS)	participant	26˙434.00

Map

Project objective

Roll-to-roll (R2R) technologies are mature core processes in manufacturing lines for graphical printing industry. In several other areas (e.g. electronics or optics) R2R techniques are emerging, being expected to notably lower the unit prices of flexible devices.

In particular, recently developed roller-based nanoimprinting methods enable unrivalled throughput and productivity for precise fabrication of micro- and nanoscale patterns. Areas that will benefit strongly from adopting such R2R nanoimprinting technologies are microfluidics and lab-on-chip products for diagnostics, drug discovery and food control. Such devices require combined printing of micro- and nanostructures and large quantities at low unit costs.

The project R2R Biofluidics aims on the development of a complete process chain for first-time realization of production lines for two selected bioanalytical lab-on-chip devices based on high-throughput R2R nanoimprinting in combination with complementary printing and manufacturing technologies.

Two types of demonstrators will be fabricated targeting application areas, which would clearly benefit from technology advancement in high volume manufacturing, show large potential for commercial exploitation and adopt current standard formats (microtiter plate and microscope slides).

Demonstrator 1 will represent an in-vitro diagnostic (IVD) chip suitable for point-of-care applications, showing improved sensitivity thanks to imprinted nanoscale optical structures and microfluidic channels. R2R fabrication will further greatly reduce production costs and increase manufacturing capacity with respect to currently used products.

Demonstrator 2 will provide a device for improved neuron based high-throughput screening assays in drug development. It will consist of nano– to microstructured, interconnected channels in combination with dedicated biofunctionalized surfaces for alignment and controlled growth of neurons.

Deliverables

List of deliverables.
Fully functional DEM1 test-chips MRSA from batch based backend processing	Demonstrators, pilots, prototypes	2020-04-06 08:39:07
Fully functional DEM2 test chips from batch based backend processes	Demonstrators, pilots, prototypes	2020-04-06 08:39:07
Roll-to-roll pilot imprinting of DEM2	Demonstrators, pilots, prototypes	2020-04-06 08:39:07
Roll-to-roll pilot imprinting of DEM1	Demonstrators, pilots, prototypes	2020-04-06 08:39:07
DEM1 with R2R top & bottom foil with batch based backend processing	Demonstrators, pilots, prototypes	2020-04-06 08:39:07
Safe-by-design report	Documents, reports	2020-04-06 08:39:06
DEM1 chips with optical nano-struct.	Demonstrators, pilots, prototypes	2020-04-06 08:39:06
DEM2 chips with radial design (Gen.2)	Demonstrators, pilots, prototypes	2020-04-06 08:39:06
Roll-to-roll pilot manufacturing line	Demonstrators, pilots, prototypes	2020-04-06 08:39:06
Public project website online	Other	2020-04-06 08:39:06

Take a look to the deliverables list in detail: detailed list of R2R Biofluidics deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2019	P. Toren, M. Rumpler, M. Smolka, A. Haase, S. Ruttloff, D. Nees, B. Stadlober, I. Katzmayr, B. Hierschlager, S. Kierstein, M. Sonnleitner, G. Bared, M. Horn, W. Weigel, J. Hesse HIGH-THROUGHPUT ROLL-TO-ROLL PRODUCTION OF BIO-FUNCTIONALIZED POLYMER COMPONENTS published pages: , ISSN: 2537-4346, DOI:	European Journal of Materials Science and Engineering	2020-04-06

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The information about "R2R BIOFLUIDICS" are provided by the European Opendata Portal: CORDIS opendata.