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FLUNOVELTY

Development of novel fluorinated reagents for preparation of drugs.

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

FLUNOVELTY project word cloud

Explore the words cloud of the FLUNOVELTY project. It provides you a very rough idea of what is the project "FLUNOVELTY" about.

20 companies compounds reactions celecoxib 136a market modern organic alternative lack elaborate around reagents drugs fluorinated struggle issue drug innovative pharmaceutical synthetic small fluorinating diazoalkanes discovering practical molecules

Project "FLUNOVELTY" data sheet

The following table provides information about the project.

Coordinator	ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS Organization address address: RUE VAUQUELIN 10 city: PARIS postcode: 75231 website: www.espci-paristech.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	https://www.lco.espci.fr/-Prof-Janine-Cossy
Total cost	92˙538 €
EC max contribution	92˙538 € (100%)
Programme	1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
Code Call	H2020-MSCA-IF-2014
Funding Scheme	MSCA-IF-EF-ST
Starting year	2015
Duration (year-month-day)	from 2015-11-01 to 2016-10-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS ECOLE SUPERIEURE DE PHYSIQUE ET DECHIMIE INDUSTRIELLES DE LA VILLE DEPARIS Organization address address: RUE VAUQUELIN 10 city: PARIS postcode: 75231 website: www.espci-paristech.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	coordinator	92˙538.00

Map

Project objective

Around 20% of all modern drugs are fluorinated organic molecules. During the recent years, however, pharmaceutical companies struggle to deliver novel drugs to the market, because of the lack of innovative practical reagents and reactions towards “drug-like” compounds. In this project, we will address this issue by discovering novel small fluorinating reagents - fluorinated diazoalkanes, - elaborate their practical reactions, and use this knowledge to develop alternative synthetic approaches to some known drugs (AS-136A, Celecoxib).

Publications

List of publications.
year	authors and title	journal	last update
2016	Anton V. Arkhipov, Viatcheslav V. Arkhipov, Janine Cossy, Volodymir O. Kovtunenko, Pavel K. Mykhailiuk Unexpected Reactivity of Trifluoromethyl Diazomethane (CF 3 CHN 2 ): Electrophilicity of the Terminal N-Atom published pages: asap, ISSN: 1523-7060, DOI: 10.1021/acs.orglett.6b01565	Organic Letters	2019-07-23
2016	Pavel K. Mykhailiuk, Aleksandr Yu. Ishchenko, Viatcheslav Stepanenko, Janine Cossy Synthesis of Fluoroalkyl Pyrazoles from In-Situ-Generated C 2 F 5 CHN 2 and Electron-Deficient Alkenes published pages: , ISSN: 1434-193X, DOI: 10.1002/ejoc.201600947	European Journal of Organic Chemistry	2019-07-23

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The information about "FLUNOVELTY" are provided by the European Opendata Portal: CORDIS opendata.