Explore the words cloud of the Amine-FUNC project. It provides you a very rough idea of what is the project "Amine-FUNC" about.
The following table provides information about the project.
Coordinator |
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
Organization address contact info |
Coordinator Country | United Kingdom [UK] |
Project website | http://www-gaunt.ch.cam.ac.uk |
Total cost | 195˙454 € |
EC max contribution | 195˙454 € (100%) |
Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
Code Call | H2020-MSCA-IF-2014 |
Funding Scheme | MSCA-IF-EF-ST |
Starting year | 2015 |
Duration (year-month-day) | from 2015-04-01 to 2017-03-31 |
Take a look of project's partnership.
# | ||||
---|---|---|---|---|
1 | THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE | UK (CAMBRIDGE) | coordinator | 195˙454.00 |
The development of new chemical transformations based on catalytic functionalization of unactivated C-H bonds has the potential to simplify the synthesis of complex molecules dramatically. Although some progress have been achieved in this emerging area, the selective transformation of aliphatic C-H bonds is still a challenge. This proposal aims to develop a new platform for the direct activation of unactivated sp3 C-H bonds of aliphatic amines and to apply this novel C(sp3)-H functionalization technology to synthesize diverse amine compounds. A key novel concept of this project is to use an unprotected aliphatic secondary amine as a native directing group, through a remarkable 4-membered-ring cyclometallation pathway. The goals of this proposal include: (I) developing unprecedented diverse C(sp3)-H functionalization of amine technology, accessing diverse functionalized amine compounds, (II) developing novel Pd-catalyzed enantioselective C-H functionalization methods to make enantioenriched chiral molecules, (III) application of this novel C(sp3)-H functionalization technology to make a library of diverse functionalized Salbutamol and Bupropion analogues, and screen them for biological and medicinal activities.
year | authors and title | journal | last update |
---|---|---|---|
2015 |
Chuan He, Matthew J. Gaunt Ligand-Enabled Catalytic CH Arylation of Aliphatic Amines by a Four-Membered-Ring Cyclopalladation Pathway published pages: 15840-15844, ISSN: 1433-7851, DOI: 10.1002/anie.201508912 |
Angewandte Chemie International Edition 54/52 | 2019-07-23 |
2017 |
Chuan He, Matthew J. Gaunt Ligand-assisted palladium-catalyzed C–H alkenylation of aliphatic amines for the synthesis of functionalized pyrrolidines published pages: , ISSN: 2041-6520, DOI: 10.1039/C7SC00468K |
Chem. Sci. | 2019-07-23 |
Are you the coordinator (or a participant) of this project? Plaese send me more information about the "AMINE-FUNC" project.
For instance: the website url (it has not provided by EU-opendata yet), the logo, a more detailed description of the project (in plain text as a rtf file or a word file), some pictures (as picture files, not embedded into any word file), twitter account, linkedin page, etc.
Send me an email (fabio@fabiodisconzi.com) and I put them in your project's page as son as possible.
Thanks. And then put a link of this page into your project's website.
The information about "AMINE-FUNC" are provided by the European Opendata Portal: CORDIS opendata.