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NBUCA

Neural and behavioral underpinnings of contextual modulations in Autism

Total Cost €

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EC-Contrib. €

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Partnership

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Project "NBUCA" data sheet

The following table provides information about the project.

Coordinator
UNIVERSITA DEGLI STUDI DI UDINE 

Organization address
address: VIA PALLADIO 8
city: UDINE
postcode: 33100
website: www.uniud.it

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country Italy [IT]
 Project website https://ezequielgrimaldi.wordpress.com
 Total cost 180˙277 €
 EC max contribution 180˙277 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-09-01   to  2017-08-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    UNIVERSITA DEGLI STUDI DI UDINE IT (UDINE) coordinator 180˙277.00

Map

 Project objective

Social cognition impairments, including deficits in nonverbal communicative behaviors used in daily life interactions are considered to be among the core deficits associated with Autism Spectrum Disorders (ASDs). So far, these deficits have been traditionally studied by using non-realistic stimuli embedded in abstract tasks. These tasks are not good models of the world because they lack the context of everyday-life situations. Although contextual processing during action comprehension has been extensively studied in other disorders (e.g. schizophrenia), much less is known about the role that it plays in ASD. Strikingly, those few studies that have used more ecological paradigms in which contextual information was given have shown that ASD individuals are able to improve their ability in reading out other’s actions. Therefore, a broader explanation of ASD which considers the influence that context, as an intrinsic part of social cognition, has on this disorder is timely and clearly required. The general aim of NBUCA is to study the neural and behavioral underpinnings of contextual modulations in ASD during action comprehension and answer many challenging questions: a) Do children and young adults with ASD have a general deficit in integrating context and behavior? If this is true, b) Does this deficit relies more on the processing of social or non-social contextual cues (or both)? Given this, an ecological context-dependent social cognition paradigm will be designed and further implemented in a set of experiments combining behavioral and psychological measures with transcranial magnetic stimulation (TMS). Overall, we expect that by enhancing contextual information ASD individuals will improve their ability in comprehending others’ actions. Together, our findings will provide novel insights on the impact that context has on ASD. This will be of clinical relevance for developing a more ecological framework that includes contextual sensitivity evaluation and treatment.

 Publications

year authors and title journal last update
List of publications.
2016 Lucia Amoruso, Alessandra Finisguerra, Cosimo Urgesi
Tracking the Time Course of Top-Down Contextual Effects on Motor Responses during Action Comprehension
published pages: 11590-11600, ISSN: 0270-6474, DOI: 10.1523/JNEUROSCI.4340-15.2016
The Journal of Neuroscience 36/46 2019-07-23
2016 Lucia Amoruso, Cosimo Urgesi
Contextual modulation of motor resonance during the observation of everyday actions
published pages: 74-84, ISSN: 1053-8119, DOI: 10.1016/j.neuroimage.2016.03.060
NeuroImage 134 2019-07-23

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