SUSAMIDE
Sustainable Synthesis of Amides
Total Cost €
0EC-Contrib. €
0Partnership
0Views
0SUSAMIDE project word cloud
Explore the words cloud of the SUSAMIDE project. It provides you a very rough idea of what is the project "SUSAMIDE" about.
Project "SUSAMIDE" data sheet
The following table provides information about the project.
| Coordinator |
UNIVERSITEIT ANTWERPEN
Organization address contact info |
| Coordinator Country | Belgium [BE] |
| Project website | https://www.facebook.com/groups/865354860229256/ |
| Total cost | 172˙800 € |
| EC max contribution | 172˙800 € (100%) |
| Programme |
1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility) |
| Code Call | H2020-MSCA-IF-2014 |
| Funding Scheme | MSCA-IF-EF-ST |
| Starting year | 2015 |
| Duration (year-month-day) | from 2015-04-01 to 2017-03-31 |
Partnership
Take a look of project's partnership.
| # | ||||
|---|---|---|---|---|
| 1 | UNIVERSITEIT ANTWERPEN | BE (ANTWERPEN) | coordinator | 172˙800.00 |
Map
Project objective
Despite the ubiquity of the amide group, its synthesis is not always straightforward and the existing methods for amide formation score badly from the perspectives of economy and sustainability. This proposal aims to develop unprecedented methodology for amide synthesis, allowing one to access “challenging” representatives. Two routes are proposed to mitigate risk and to provide complementarity. The objective of the proposal is twofold: 1) to expand the available chemical space (allowing one to synthesize challenging amides previously considered inaccessible via library synthesis with existing methods) and 2) to substitute existing syntheses with better ones (delivering higher yields without using toxic reagents and minimizing waste). Achieving these two objectives will have an impact on the discovery of new molecular entities and the improvement of production processes in the fine chemicals sector. The power of the new methodology will be demonstrated on the synthesis of selected real-life examples, APIs (Active Pharmaceutical Ingredients).
Publications
| year | authors and title | journal | last update |
|---|---|---|---|
| 2016 |
Pieter Mampuys, Yanping Zhu, Sergey Sergeyev, Eelco Ruijter, Romano V. A. Orru, Sabine Van Doorslaer, Bert U. W. Maes Iodide-Catalyzed Synthesis of Secondary Thiocarbamates from Isocyanides and Thiosulfonates published pages: 2808-2811, ISSN: 1523-7060, DOI: 10.1021/acs.orglett.6b01023 |
Organic Letters 18/12 | 2019-07-24 |
| 2016 |
Yan-Ping Zhu, Sergey Sergeyev, Philippe Franck, Romano V. A. Orru, Bert U. W. Maes Amine Activation: Synthesis of N -(Hetero)arylamides from Isothioureas and Carboxylic Acids published pages: 4602-4605, ISSN: 1523-7060, DOI: 10.1021/acs.orglett.6b02247 |
Organic Letters 18/18 | 2019-07-24 |
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