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LIVING LASERS

Living cell lasers: intracellular lasing induced by natural and polymeric microscopic resonators

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EC-Contrib. €

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Partnership

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Project "LIVING LASERS" data sheet

The following table provides information about the project.

Coordinator
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS 

Organization address
address: NORTH STREET 66 COLLEGE GATE
city: ST ANDREWS
postcode: KY16 9AJ
website: www.st-andrews.ac.uk

contact info
title: n.a.
name: n.a.
surname: n.a.
function: n.a.
email: n.a.
telephone: n.a.
fax: n.a.

 Coordinator Country United Kingdom [UK]
 Project website http://gatherlab.wp.st-andrews.ac.uk/people/
 Total cost 195˙454 €
 EC max contribution 195˙454 € (100%)
 Programme 1. H2020-EU.1.3.2. (Nurturing excellence by means of cross-border and cross-sector mobility)
 Code Call H2020-MSCA-IF-2014
 Funding Scheme MSCA-IF-EF-ST
 Starting year 2015
 Duration (year-month-day) from 2015-08-01   to  2017-07-31

 Partnership

Take a look of project's partnership.

# participants  country  role  EC contrib. [€] 
1    THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS UK (ST ANDREWS) coordinator 195˙454.00

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 Project objective

Can a living cell be turned into a laser? By aiming to coalesce biological cells with laser light, the most versatile tool that modern photonics has developed, LIVING LASERS explores entirely new ways to develop fully biocompatible lasers.

The ability of vitamins, bacteria and even living cells to generate laser light has been recently demonstrated by the supervisor of the project, Prof Malte Gather. However, these and other experiments with active biological gain media are so far limited by the rigid and synthetic nature of the optical resonators, an essential part of any laser device. Introducing lasing in living cells independent of external resonators necessitates a conceptual change of the laser design. This is realized by internalization of microscopic resonators that will transfer the optical feedback directly into the cell. It is the main goal of this interdisciplinary project, located at the interface between material sciences, laser physics, photonics and biology, to demonstrate autonomous single cell lasing. Consequently, LIVING LASERS can be expected to start a whole new field in biophotonics and will help to overcome the boundaries between living nature and nowadays highly artificial and harmful laser technologies.

 Publications

year authors and title journal last update
List of publications.
2017 Marcel Schubert Schubert, Malte C. Gather
Microscopic intracellular lasers tag individual cells over several generations
published pages: , ISSN: 1818-2259, DOI: 10.1117/2.1201704.006899
SPIE Newsroom 2019-07-24
2017 M Karl, C P Dietrich, M Schubert, I D W Samuel, G A Turnbull, M C Gather
Single cell induced optical confinement in biological lasers
published pages: 84005, ISSN: 0022-3727, DOI: 10.1088/1361-6463/aa5367
Journal of Physics D: Applied Physics 50/8 2019-07-24
2017 Marcel Schubert, Klara Volckaert, Markus Karl, Andrew Morton, Philipp Liehm, Gareth B. Miles, Simon J. Powis, Malte C. Gather
Lasing in Live Mitotic and Non-Phagocytic Cells by Efficient Delivery of Microresonators
published pages: 40877, ISSN: 2045-2322, DOI: 10.1038/srep40877
Scientific Reports 7 2019-07-24
2016 C. P. Dietrich, A. Steude, L. Tropf, M. Schubert, N. M. Kronenberg, K. Ostermann, S. Ho fling, M. C. Gather
An exciton-polariton laser based on biologically produced fluorescent protein
published pages: e1600666-e160066, ISSN: 2375-2548, DOI: 10.1126/sciadv.1600666
Science Advances 2/8 2019-07-24
2016 Markus Karl, Guy L. Whitworth, Marcel Schubert, Christof P. Dietrich, Ifor D. W. Samuel, Graham A. Turnbull, Malte C. Gather
Optofluidic distributed feedback lasers with evanescent pumping: Reduced threshold and angular dispersion analysis
published pages: 261101, ISSN: 0003-6951, DOI: 10.1063/1.4954650
Applied Physics Letters 108/26 2019-07-24
2017 Christof P. Dietrich, Anja Steude, Marcel Schubert, Jürgen Ohmer, Utz Fischer, Sven Höfling, Malte C. Gather
Strong Coupling in Fully Tunable Microcavities Filled with Biologically Produced Fluorescent Proteins
published pages: 1600659, ISSN: 2195-1071, DOI: 10.1002/adom.201600659
Advanced Optical Materials 5/1 2019-07-24

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