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PRETREAT TERMINATED

PRoteome-based assessment of vascular disease for the Establishment of a Translational REsearch plATform

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

PRETREAT project word cloud

Explore the words cloud of the PRETREAT project. It provides you a very rough idea of what is the project "PRETREAT" about.

urinary flowing pathophysiology academic obtaining automatically serve platform protein body combine chain 2018 animal efficiency blood joint utility extensive prepare secondments morbidity webinars builds monthly situ training mechanisms complete identification keep detect exchange create disease detection train vd expertise sustainability medicine tools centric worldwide biology services molecular generate clinical sme peptidomics fluid pillars drug establishment vascular mortality readouts disciplinary combined totaling decipher proteomics proof treatment preclinical sysvasc additional human similarity models markers of parallel database link peptides individual stratify 2014 humans humanized pretreat 27 bioinformatics cardiovascular workshops fp7

Project "PRETREAT" data sheet

The following table provides information about the project.

Coordinator	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	France [FR]
Project website	http://www.pretreat.eu
Total cost	387˙000 €
EC max contribution	387˙000 € (100%)
Programme	1. H2020-EU.1.3.3. (Stimulating innovation by means of cross-fertilisation of knowledge)
Code Call	H2020-MSCA-RISE-2015
Funding Scheme	MSCA-RISE
Starting year	2016
Duration (year-month-day)	from 2016-01-01 to 2019-12-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE Organization address address: RUE DE TOLBIAC 101 city: PARIS postcode: 75654 website: www.inserm.fr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	FR (PARIS)	coordinator	94˙500.00
2	MOSAIQUES DIAGNOSTICS GMBH MOSAIQUES DIAGNOSTICS GMBH Organization address address: ROTENBURGER STRASSE 20 city: HANNOVER postcode: 30659 website: www.mosaiques-diagnostics.com contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	DE (HANNOVER)	participant	148˙500.00
3	IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON IDRYMA IATROVIOLOGIKON EREUNON AKADEMIAS ATHINON Organization address address: SORANOU EFESIOU 4 city: ATHINA postcode: 115 27 website: www.bioacademy.gr contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHINA)	participant	90˙000.00
4	HYBRIDSTAT PREDICTIVE ANALYTICS OE HYBRIDSTAT PREDICTIVE ANALYTICS OE Organization address address: AIOLOU 19 city: ATHENS postcode: 10551 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	EL (ATHENS)	participant	54˙000.00
5	EMERGENTEC BIODEVELOPMENT GMBH EMERGENTEC BIODEVELOPMENT GMBH Organization address address: GERSTHOFER STRASSE 29-31 city: VIENNA postcode: 1180 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	AT (VIENNA)	participant	0.00

Map

Project objective

Cardiovascular disease (VD) is the leading cause of mortality and morbidity in Europe and worldwide. The objective of the PRETREAT consortium is to generate a joint SME/academic European preclinical platform for providing services for detection of VD and drug development. This platform will combine the use of urinary and/or blood peptidomics in humans and in preclinical animal models of VD, together with bioinformatics and systems biology, in order to better detect, stratify and decipher the molecular mechanisms of VD, develop new animal models with high similarity to human disease, and provide new tools for obtaining information on novel drug targets. PRETREAT builds on the FP7 project Sysvasc (systems biology to identify molecular targets for vascular disease treatment, 2014-2018) and the combined expertise of the PRETREAT partners in clinical proteomics, proteomics, animal models and system medicine as the pillars to implement this platform. The work will be carried out in an extensive exchange program totaling 27 secondments. Main objectives during the secondments include establishment of the link between urinary markers and the pathophysiology of VD, identification of additional animal VD models with similarity to human VD, development of “humanized” body fluid readouts in VD models, establishment of a VD protein-centric database in order to automatically link urinary peptides to in situ changes and provide information on drug targets, and provide proof-of-concept of the utility of the proposed platform. These secondments will in parallel serve to keep information flowing within the project, increase individual research efficiency and create a multi-disciplinary working chain, train personnel, and prepare the sustainability of the results after the project. To complete training, 3 monthly webinars and four workshops are planned.

Deliverables

List of deliverables.
PRETREAT flyer	Websites, patent fillings, videos etc.	2019-05-31 17:27:28
PRETREAT public webpage ready	Websites, patent fillings, videos etc.	2019-05-31 17:27:27

Take a look to the deliverables list in detail: detailed list of PRETREAT deliverables.

Publications

List of publications.
year	authors and title	journal	last update
2016	Mercedes Arguello Casteleiro, Julie Klein, Robert Stevens The Proteasix Ontology published pages: , ISSN: 2041-1480, DOI: 10.1186/s13326-016-0078-9	Journal of Biomedical Semantics 7/1	2019-06-17

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The information about "PRETREAT" are provided by the European Opendata Portal: CORDIS opendata.