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DeTOP SIGNED

Dexterous Transradial Osseointegrated Prosthesis with neural control and sensory feedback

Total Cost €

EC-Contrib. €

Partnership

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Outcomes and
results

DeTOP project word cloud

Explore the words cloud of the DeTOP project. It provides you a very rough idea of what is the project "DeTOP" about.

limb disjointed aside poor detop prosthetic pioneered mechanical implant proven interface safe smart clinically action centre coupling skeletal implanted trl prostheses solution transradial patients osseointegration mainly efficient limbs purposely critically electrodes shown quality neural ago interfaces bidirectional bridges made direct scientific implantable patient assessing superficial engineers recovery decades push powered feedback artificial amputation continue neuroscientists clinicians neuromuscular despite amputees functional stable attachment life perception clinical natural interfacing controllability dependent technique function suited myoelectric technologies paradigms mechatronic surface boundaries prosthesis communication sensory upper technological arm population

Project "DeTOP" data sheet

The following table provides information about the project.

Coordinator	SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO S ANNA Organization address address: PIAZZA MARTIRI DELLA LIBERTA 33 city: PISA postcode: 56127 website: www.sssup.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.
Coordinator Country	Italy [IT]
Project website	http://www.detop-project.eu
Total cost	5˙165˙158 €
EC max contribution	4˙260˙521 € (82%)
Programme	1. H2020-EU.2.1.1. (INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT))
Code Call	H2020-ICT-2015
Funding Scheme	RIA
Starting year	2016
Duration (year-month-day)	from 2016-03-01 to 2020-05-31

Partnership

Take a look of project's partnership.

#	participants	country	role	EC contrib. [€]
1	SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO S ANNA SCUOLA SUPERIORE DI STUDI UNIVERSITARI E DI PERFEZIONAMENTO S ANNA Organization address address: PIAZZA MARTIRI DELLA LIBERTA 33 city: PISA postcode: 56127 website: www.sssup.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PISA)	coordinator	778˙050.00
2	INTEGRUM AB INTEGRUM AB Organization address address: KROKSLATTS FABRIKER 50 city: MOLNDAL postcode: 431 37 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (MOLNDAL)	participant	1˙419˙450.00
3	LUNDS UNIVERSITET LUNDS UNIVERSITET Organization address address: Paradisgatan 5c city: LUND postcode: 22100 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (LUND)	participant	538˙827.00
4	UNIVERSITY OF ESSEX UNIVERSITY OF ESSEX Organization address address: WIVENHOE PARK city: COLCHESTER postcode: CO4 3SQ website: www.essex.ac.uk contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	UK (COLCHESTER)	participant	528˙370.00
5	GOETEBORGS UNIVERSITET GOETEBORGS UNIVERSITET Organization address address: VASAPARKEN city: GOETEBORG postcode: 405 30 website: www.gu.se contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	SE (GOETEBORG)	participant	517˙050.00
6	PRENSILIA SRL PRENSILIA SRL Organization address address: VIA RINALDO PIAGGIO 32 city: PONTEDERA PI postcode: 56025 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (PONTEDERA PI)	participant	412˙973.00
7	UNIVERSITA CAMPUS BIO MEDICO DI ROMA UNIVERSITA CAMPUS BIO MEDICO DI ROMA Organization address address: VIA ALVARO DEL PORTILLO 21 city: ROMA postcode: 128 website: www.unicampus.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	50˙000.00
8	ISTITUTO ORTOPEDICO RIZZOLI ISTITUTO ORTOPEDICO RIZZOLI Organization address address: VIA DI BARBIANO 1/10 city: BOLOGNA postcode: 40136 website: www.ior.it contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (BOLOGNA)	participant	15˙800.00
9	CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT CSEM CENTRE SUISSE D'ELECTRONIQUE ET DE MICROTECHNIQUE SA - RECHERCHE ET DEVELOPPEMENT Organization address address: RUE JAQUET DROZ 1 city: NEUCHATEL postcode: 2000 website: www.csem.ch contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	CH (NEUCHATEL)	participant	0.00
10	ISTITUTO NAZIONALE ASSICURAZIONE INFORTUNI SUL LAVORO INAIL ISTITUTO NAZIONALE ASSICURAZIONE INFORTUNI SUL LAVORO INAIL Organization address address: VIA IV NOVEMBRE 144 city: ROMA postcode: 187 website: n.a. contact info title: n.a. name: n.a. surname: n.a. function: n.a. email: n.a. telephone: n.a. fax: n.a.	IT (ROMA)	participant	0.00

Map

Project objective

This project addresses the scientific, technological and clinical problem of recovery of hand function after amputation. Despite decades of research and development on artificial limbs and neural interfaces, amputees continue to use technology for powered prostheses developed over 40 years ago, namely myoelectric prostheses controlled via superficial electrodes. These devices do not purposely provide sensory feedback and are known for their poor functionality, controllability and sensory feedback, mainly due to the use of surface electrodes.

The consortium has pioneered the use of osseointegration as a long-term stable solution for the direct skeletal attachment of limb prostheses. This technology aside from providing an efficient mechanical coupling, which on its own has shown to improve prosthesis functionality and the patient’s quality of life, can also be used as a bidirectional communication interface between implanted electrodes and the prosthetic arm. This is today the most advanced and unique technique for bidirectional neuromuscular interfacing, suited for the upper limb amputees, which was proven functional in the long term. The goal of the DeTOP project is to push the boundaries of this technology –made in Europe– to the next TRL and to make it clinically available to the largest population of upper limb amputees, namely transradial amputees. This objective will be targeted by developing a novel prosthetic hand with improved functionality, smart mechatronic devices for safe implantable technology, and by studying and assessing paradigms for natural control (action) and sensory feedback (perception) of the prosthesis through the implant. The novel technologies and findings will be assessed by three selected patients, implanted in a clinical centre.

DeTOP bridges several currently disjointed scientific fields and is therefore critically dependent on the collaboration of engineers, neuroscientists and clinicians.

Publications

List of publications.
year	authors and title	journal	last update
2018	Ahmed W. Shehata, Leonard F. Engels, Marco Controzzi, Christian Cipriani, Erik J. Scheme, Jonathon W. Sensinger Improving internal model strength and performance of prosthetic hands using augmented feedback published pages: , ISSN: 1743-0003, DOI: 10.1186/s12984-018-0417-4	Journal of NeuroEngineering and Rehabilitation 15/1	2020-04-14
2017	Francesco Clemente, Bo HÃ¥kansson, Christian Cipriani, Johan Wessberg, Katarzyna Kulbacka-Ortiz, Rickard BrÃ¥nemark, Karl-Johan FredÃ©n Jansson, Max Ortiz-Catalan Touch and Hearing Mediate Osseoperception published pages: 45363, ISSN: 2045-2322, DOI: 10.1038/srep45363	Scientific Reports 7	2020-04-14
2016	Federico Montagnani, Marco Controzzi, Christian Cipriani Independent Long Fingers are not Essential for a Grasping Hand published pages: , ISSN: 2045-2322, DOI: 10.1038/srep35545	Scientific Reports 6/1	2020-04-14
2018	Mohamed Aboseria, Francesco Clemente, Leonard F. Engels, Christian Cipriani Discrete Vibro-Tactile Feedback Prevents Object Slippage in Hand Prostheses More Intuitively Than Other Modalities published pages: 1577-1584, ISSN: 1534-4320, DOI: 10.1109/TNSRE.2018.2851617	IEEE Transactions on Neural Systems and Rehabilitation Engineering 26/8	2020-04-14
2018	Alexander Thesleff, Rickard BrÃ¥nemark, Bo HÃ¥kansson, Max Ortiz-Catalan Biomechanical Characterisation of Bone-anchored Implant Systems for Amputation Limb Prostheses: A Systematic Review published pages: 377-391, ISSN: 0090-6964, DOI: 10.1007/s10439-017-1976-4	Annals of Biomedical Engineering 46/3	2020-04-14
2018	Gunter Kanitz, Federico Montagnani, Marco Controzzi, Christian Cipriani Compliant Prosthetic Wrists Entail More Natural Use Than Stiff Wrists During Reaching, Not (Necessarily) During Manipulation published pages: 1407-1413, ISSN: 1534-4320, DOI: 10.1109/TNSRE.2018.2847565	IEEE Transactions on Neural Systems and Rehabilitation Engineering 26/7	2020-04-14
2017	Enzo Mastinu, Pascal Doguet, Yohan Botquin, Bo Hakansson, Max Ortiz-Catalan Embedded System for Prosthetic Control Using Implanted Neuromuscular Interfaces Accessed Via an Osseointegrated Implant published pages: 867-877, ISSN: 1932-4545, DOI: 10.1109/TBCAS.2017.2694710	IEEE Transactions on Biomedical Circuits and Systems 11/4	2020-04-14
2018	NebojÅ¡a MaleÅ¡eviÄ‡, Dimitrije MarkoviÄ‡, Gunter Kanitz, Marco Controzzi, Christian Cipriani, Christian Antfolk Vector Autoregressive Hierarchical Hidden Markov Models for Extracting Finger Movements Using Multichannel Surface EMG Signals published pages: 1-12, ISSN: 1076-2787, DOI: 10.1155/2018/9728264	Complexity 2018	2020-04-14
2017	Niclas Nilsson, Bo HÃ¥kansson, Max Ortiz-Catalan Classification complexity in myoelectric pattern recognition published pages: , ISSN: 1743-0003, DOI: 10.1186/s12984-017-0283-5	Journal of NeuroEngineering and Rehabilitation 14/1	2020-04-14
2018	Enzo Mastinu, Johan Ahlberg, Eva Lendaro, Liselotte Hermansson, Bo Hakansson, Max Ortiz-Catalan An Alternative Myoelectric Pattern Recognition Approach for the Control of Hand Prostheses: A Case Study of Use in Daily Life by a Dysmelia Subject published pages: 1-12, ISSN: 2168-2372, DOI: 10.1109/JTEHM.2018.2811458	IEEE Journal of Translational Engineering in Health and Medicine 6	2020-04-14

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